Tietze's Syndrome (Tietze Syndrome)

Idiopathic painful nonsuppurative swellings of one or more costal cartilages, especially of the second rib. The anterior chest pain may mimic that of coronary artery disease. (Dorland, 27th ed.)

Also Known As:

Networked: 33 relevant articles (4 outcomes, 4 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Pain (Aches)
2.	Neoplasms (Cancer)
3.	Lung Neoplasms (Lung Cancer)
4.	Empyema
5.	Dermatitis

Experts

1.	Ağababaoğlu, İsmail: 1 article (04/2021)
2.	Yıldız, Özgür Ömer: 1 article (04/2021)
3.	Çınar, Eray: 1 article (04/2021)
4.	İnan, Kubilay: 1 article (04/2021)
5.	Cho, Ju Young: 1 article (01/2019)
6.	Park, Donghwi: 1 article (01/2019)
7.	Oh, Hong Chul: 1 article (11/2018)
8.	Oh, Jeong Hee: 1 article (11/2018)
9.	Park, Soo Bin: 1 article (11/2018)
10.	Gologorsky, Rebecca: 1 article (12/2017)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Tietze's Syndrome:

1.	SteroidsIBA 05/01/1997 - "Local steroid injection proved to be clinically safe and effective in the treatment of patients with Tietze's syndrome." 05/01/1997 - "The purpose of this study was to investigate the value of ultrasonographic examination in the diagnosis of Tietze's syndrome and assessment of the changes in costal cartilage following local steroid injection. " 05/01/1997 - "Ultrasonographic assessment of local steroid injection in Tietze's syndrome." 12/01/2022 - "The aim of this study was to assess the efficacy of adding oral steroids in addition to other non- steroidal treatment in improvement of pain and quality of life (QOL) in patients with Tietze syndrome. " 01/01/1959 - "Tietze's syndrome (painful nonsuppurative swelling of costochondral cartilages); report of a case in a patient with bronchial asthma treated with steroids."
2.	Adrenal Cortex Hormones (Corticosteroids)IBA 12/01/2022 - "The efficacy of oral corticosteroids for treatment of Tietze syndrome: A pragmatic randomized controlled trial." 01/01/2019 - "Moreover, there has been no research investigating images of ultrasound-guided corticosteroid injection, although corticosteroid injection is one of the most important treatments for Tietze syndrome. " 01/01/2019 - "Ultrasound-Guided Corticosteroid Injection in a Patient With Tietze Syndrome Combined With Costochondral Joint Swelling." 04/01/1999 - "Tietze's syndrome was diagnosed and the patients were treated with non-steroidal anti-inflammatory drugs and a local injection of corticosteroid. " 12/01/2022 - "In this study, addition of short-term oral corticosteroids showed a clear benefit for use at 1, 2 and 3 weeks in improvement of pain and QOL in patients with Tietze syndrome. "
3.	Local AnestheticsIBA 04/01/2021 - "Our treatment approach involving injection of a mixture of steroid and a local anesthetic provides a rapid relief from pain, irrespective of age, sex, or employment status in patients diagnosed with Tietze syndrome."
4.	Triamcinolone (Aristocort)FDA Link 04/01/2021 - "In this study, we present our experiences with local injections of triamcinolone and prilocaine in patients diagnosed with Tietze syndrome. "
5.	Prilocaine (Citanest)FDA LinkGeneric 04/01/2021 - "In this study, we present our experiences with local injections of triamcinolone and prilocaine in patients diagnosed with Tietze syndrome. "
6.	Allopurinol (Remid)FDA LinkGeneric 03/01/1972 - "[Tietze's syndrome--therapeutic trial with allopurinol]."
7.	Prednisolone (Predate)FDA LinkGeneric 06/27/2013 - "One month later a presumptive diagnosis of Tietze syndrome was made and he was prescribed prednisolone (60mg/day) for 3 weeks. " 12/01/2022 - "Forty patients with Tietze syndrome were randomly divided into two treatment groups: (1) One week of prednisolone 40 mg daily followed by 1 week of prednisolone 20 mg daily followed by 1 week of 10 mg with 3 weeks of non-steroidal anti-inflammatory drug (NSAID) treatment (n = 20); (2) three weeks of NSAID treatment only (n = 20). "
8.	PolyestersIBA 01/01/1996 - "From January 1987 through December 1994, we performed chest wall reconstruction using the polyester mesh in 15 patients with lung cancer, 11 with empyema after open drainage, 8 with chest wall tumor and 1 with radiation dermatitis and costal chondritis. " 04/01/1992 - "From January 1987 through July 1991, we performed chest wall reconstruction using the polyester mesh in 8 patients with lung cancer, 9 with empyema after open drainage, 2 with metastatic chest wall tumors, 1 with a primary osteogenic giant cell tumor originating from the rib and 1 with radiation dermatitis and costal chondritis. "
9.	Hydrocortisone (Cortisol)FDA LinkGeneric 11/19/1955 - "[Tietze syndrome; successive treatment with hydrocortisone]." 08/17/1985 - "Patients with Tietze's syndrome did not respond to drug therapy, but 7 out of 10 responded to injection of lignocaine and hydrocortisone around the affected costochondral junction."
10.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 11/01/2018 - "18F-FDG PET/CT and Bone Scintigraphy Findings in Tietze Syndrome."

Therapies and Procedures

1.	Debridement 03/01/2015 - "Nine patients (4. 7%) did not recover, due to residue of the sequestrum and costal chondritis, whom were later cured by undergoing a second treatment of debridement and pectoralis major muscle flap transposition. "
2.	Injections 04/01/2021 - "In this study, we present our experiences with local injections of triamcinolone and prilocaine in patients diagnosed with Tietze syndrome. "
3.	Therapeutics 09/01/1997 - "Stellate ganglion block therapy for a patient with Tietze's syndrome." 11/01/1957 - "[Roentgen minimal dose therapy in Tietze syndrome]." 09/22/2017 - "Prolotherapy: An effective therapy for Tietze syndrome." 05/09/1963 - "[Contribution to the differential diagnosis and therapy of chest pain, Tietze's syndrome; a report of 31 cases]." 01/01/1985 - "Experience with the use of human calcitonin in five patients suffering from severe Tietze's syndrome who did not respond to conventional therapy is reported. "
4.	Radiotherapy 01/01/1971 - "[Radiotherapy of Tietze's syndrome]." 02/01/1970 - "[Radiotherapy of costal cartilage in Tietze's syndrome]."
5.	Sternotomy 01/01/1984 - "[Costal chondritis as a complication of purulent mediastinitis following median sternotomy]."