A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR PITUITARY GLAND.
Also Known As:
Protirelin; Thypinone; Abbott-38579; Antepan; Proterelin Tartrate; Proterelin Tartrate Hydrate; Protirelin Tartrate (1:1); Relefact TRH; Stimu-TSH; TRH Ferring; TRH Prem; Thyroliberin TRH Merck; Thyrotropin-Releasing Factor; Thyrotropin-Releasing Hormone Tartrate; Abbott 38579; Abbott38579; Hydrate, Proterelin Tartrate; Prem, TRH; Stimu TSH; StimuTSH; TRH, Relefact; Tartrate Hydrate, Proterelin; Thyrotropin Releasing Factor; Thyrotropin Releasing Hormone; Thyrotropin Releasing Hormone Tartrate; Thyroliberin; pyroGlu-His-Pro-NH2 (or 5-oxo-L-prolyl-L-histidyl-L-prolinamide)