Antithyroid Agents (Antithyroid Drugs)

08/01/1989 - "Studies were performed on 42 unselected clinically euthyroid patients with Graves' disease under maintenance doses of antithyroid drugs for various clinical parameters to determine the remission rate and to investigate which parameters carry weight in determining the outcome of the disease and could be good predictive factors. "
06/01/2005 - "The treatment of Graves' disease (GD) with antithyroid drugs (ATD) leads to remission of the disease in approximately half of patients treated for at least six months, and the overall relapse rate is high, ranging from 60% to 80%. "
05/01/2005 - "There is no comparative cost-utility study between 131I therapy and antithyroid drugs (ATD) therapy for Graves' disease, though 131I therapy has higher remission rate and less side effects. "
05/15/2000 - "Surgery for Graves' disease was largely replaced in the mid-1900s by radioiodine and antithyroid drugs, due to the belief that they were more safe and effective. "
01/01/1994 - "Sustained remission can be observed among 30-50% of the patients long-term treated with antithyroid drugs for Graves' disease. "

03/01/1997 - "Effective treatment of fetal hyperthyroidism in pregnant women with high titers of thyroid stimulating autoantibody is possible by judicious administration of antithyroid drugs to the mother. "
02/20/1976 - "QKd is useful index not only for the rapid assessment of thyroid function as proposed by previous investigaters, but also for the rpaid evaluation of efficacy of antithyroid drugs administered in hyperthyroidism."
01/01/1995 - "All patients were treated with antithyroid drugs for at least 12 months; 29 patients had stable remission 24 or more months after withdrawal of treatment; 76 patients had persistent disease--66 unremitting/relapsing hyperthyroidism, 10 stable hypothyroidism--36 or more months after onset of disease. "
02/01/1983 - "If great care is taken to avoid overtreatment of the fetus, the treatment with antithyroid drugs is superior to surgical treatment, since surgery completely neglects the problem of fetal hyperthyroidism."
06/01/2013 - "TRAb can accurately predict short-term relapses of hyperthyroidism after a course of antithyroid drugs but are less effective in predicting long-term relapses or remissions. "

09/01/2010 - "Antithyroid drugs (ATD) are used as a first line treatment in thyrotoxicosis. "
07/01/2006 - "Antithyroid drugs should remain the first-line therapy for treatment of thyrotoxicosis in children with a remission rate of 66.7%. "
09/15/2013 - "Antithyroid drugs as thionamides are largely used in the treatment of the thyrotoxicosis. "
12/01/2012 - "There are 3 treatment options for thyrotoxicosis: Antithyroid drugs, Surgery and radioiodine. "
01/01/2012 - "Antithyroid drugs (ATDs) have been widely and effectively used for the treatment of pediatric and adult thyrotoxicosis for more than a half century. "

07/01/2011 - "Maternal overtreatment with antithyroid drugs can induce fetal goitrous hypothyroidism. "
06/01/2011 - "Common and typical adverse reactions of antithyroid drugs include dose dependent hypothyroidism and thus thyroid function should be repeatedly checked while the patient is on antithyroid drugs. "
03/10/2007 - "Antithyroid drugs potentially increase rates of failure and reduce rates of hypothyroidism if they are given in the week before or after radioiodine treatment, respectively."
03/10/2007 - "Pooled relative risks for treatment failure and hypothyroidism after radioiodine treatment with and without adjunctive antithyroid drugs were calculated with a random effects model. "
03/10/2007 - "To determine the effect of adjunctive antithyroid drugs on the risk of treatment failure, hypothyroidism, and adverse events after radioiodine treatment. "

01/01/2007 - "Patients with thyroiditis or long history of antithyroid drugs for more than one year were excluded from the study. "
04/01/2012 - "The discussed case shows difficulties in diagnosis of inflammatory processes in the thyroid gland and indicates that antithyroid drugs may be effective agents in hyperthyroid patients with painful Hashimoto's thyroiditis."
09/06/1951 - "Treatment of acute thyroiditis with antithyroid drugs."
01/01/1988 - "The possible immunosuppressive action of antithyroid drugs in vivo has been assessed using Buffalo (Buf) strain rats with thyroiditis produced by neonatal thymectomy; this model shares many features with spontaneous thyroiditis in man. "
09/12/1992 - "Antithyroid drugs, concentrated within thyroid cells, will prevent the release of these inflammatory molecules, which may in turn explain the amelioration of thyroiditis and remission of Graves' disease after such treatment."