Thymidine Phosphorylase

07/01/2001 - "These results suggest that transduction of thymidine phosphorylase may be a beneficial approach to increasing the efficacy of cd/5-FC suicide gene therapy in certain types of tumor."
07/01/1999 - "The present study suggests that inhibitors of PD-ECGF/TP, which have been recently developed and are under laboratory investigation to test their effectiveness as treatments for various types of cancer, may not be effective against SCLC."
01/01/2020 - "Thymidine phosphorylase and prostrate cancer cell proliferation inhibitory activities of synthetic 4-hydroxybenzohydrazides: In vitro, kinetic, and in silico studies."
06/01/2010 - "The aim of the present study was to elucidate the etiological roles of Epstein-Barr virus (EBV) in the development of EBV-associated GC (EBV-GC), EBV-GCs and non EBV-GCs were compared with regard to the expression of thymidine phosphorylase (TP), which is known to have angiogenic activity in various tumor tissues. "
05/01/2004 - "To study the thymidine phosphorylase (TP) expression in different types of cancer and its correlation with tumor microvessel density (MVD). "

08/28/2018 - "Objective: To study the association between Thymidine Phosphorylase (TYMP) genetic variation and clinical outcomes and safety of postoperative colorectal cancer (CRC) patients. "
12/01/2004 - "This study aimed to clarify the role and localization of platelet-derived endothelial cell growth factor associated with human colorectal cancer invasion. "
04/01/2004 - "The aim of this study is to clarify the prognostic value of PD-ECGF expression in colorectal carcinomas. "
09/01/2022 - "Impact of thymidine phosphorylase and CD163 expression on prognosis in stage II colorectal cancer."
07/01/2021 - "Targeting thymidine phosphorylase inhibition in human colorectal cancer xenografts."

03/01/1999 - "In this study we investigated the production of dThdPase/platelet-derived endothelial cell growth factor in gastric cancer quantitatively. "
02/01/1998 - "In this study, we examined the role of PD-ECGF in the angiogenesis of human gastric cancer. "
12/01/2022 - "The Association of Thymidine Phosphorylase with Gastric Cancer Prognosis."
01/01/2019 - "The inhibition of thymidine phosphorylase can reverse acquired 5FU-resistance in gastric cancer cells."
07/12/2016 - "We explored its prognostic value in localized gastric cancer (GC) after R0 resection and the potential associations with Thymidine phosphorylase (TYMP), which was reported to increase the migration and invasion of gastric cancer cells. "

06/01/2016 - "A positive correlation was found between DPI value and PD-ECGF expression in patients with liver metastases (p < 0.05). "
06/01/2016 - "PD-ECGF expression in patients with colorectal liver metastases was significantly higher than that in the group without liver metastases (p < 0.05). "
06/01/2016 - "Effects of Platelet-Derived Endothelial Cell Growth Factor and Doppler Perfusion Index in Patients with Colorectal Hepatic Metastases."
06/01/2008 - "Thymidine phosphorylase (TP) is over-expressed in various tumour types and plays an important role in tumour angiogenesis, growth, invasion and metastasis. "
10/01/2000 - "Suppression of metastasis by thymidine phosphorylase inhibitor."

11/01/2002 - "In this study we investigated the distribution of thymidine phosphorylase activity in human gastric carcinoma or normal gastric tissue using the ELISA system. "
11/15/2001 - "This is the first study on the quantitative assessment of thymidine phosphorylase (TP) activity in patients with nonsmall lung carcinoma. "
07/01/2012 - "[Influence of interferon-α2a on thymidine phosphorylase expression and anticancer activity of 5'-deoxy-fluorouridine in human colon carcinoma cell lines LOVO and SW480]."
01/01/2011 - "[Ki-67 expression, thymidine phosphorylase and PTEN in intraepithelial cervical carcinoma]."
06/01/2010 - "Frequent expression of thymidine phosphorylase in Epstein-Barr virus-associated gastric carcinoma of diffuse type."