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Thiotepa (Triethylenethiophosphoramide)

A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Also Known As:
Triethylenethiophosphoramide; AI3-24916; Girostan; NSC-6396; Tespa; Tespamin; Tris(1-aziridinyl)phosphine Sulfide; AI3 24916; AI324916; NSC 6396; NSC6396; Thio Tepa; Thio-Tepa; Thiophosphamide; Aziridine, 1,1',1''-phosphinothioylidynetris-
Networked: 1139 relevant articles (101 outcomes, 196 trials/studies)

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Drug Context: Research Results

Experts

1. Mohty, Mohamad: 14 articles (01/2022 - 01/2016)
2. Labopin, Myriam: 12 articles (01/2022 - 01/2016)
3. Nagler, Arnon: 11 articles (01/2022 - 01/2016)
4. Finlay, Jonathan L: 8 articles (01/2018 - 11/2003)
5. Rodenhuis, S: 8 articles (04/2006 - 01/2001)
6. Dunkel, Ira J: 7 articles (11/2022 - 05/2004)
7. Finke, Jürgen: 7 articles (11/2017 - 08/2006)
8. Angelucci, Emanuele: 6 articles (01/2022 - 01/2018)
9. Rambaldi, Alessandro: 6 articles (01/2022 - 01/2002)
10. Arcese, William: 6 articles (01/2021 - 01/2016)

Related Diseases

1. Neoplasms (Cancer)
2. Lymphoma (Lymphomas)
3. Breast Neoplasms (Breast Cancer)
4. Urinary Bladder Neoplasms (Bladder Cancer)
5. Leukemia

Related Drugs and Biologics

1. Cyclophosphamide (Cytoxan)
2. Busulfan (Busulfex)
3. Melphalan (Alkeran)
4. Carboplatin (JM8)
5. fludarabine
6. Doxorubicin (Adriamycin)
7. Mitomycin (Mitomycin-C)
8. Etoposide (VP 16)
9. Methotrexate (Mexate)
10. Cisplatin (Platino)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Stem Cell Transplantation
4. Intravesical Administration
5. Transplantation