Thiamine (Aneurin)

01/01/2013 - "Determination of thiamine status may be considered and corrected among patients with, or at high risk for, MetS, but the question whether thiamine deficiency correction translates to improved cardiometabolic status needs further longitudinal investigation."
05/01/1997 - "Thiamine deficiency appears to play a key role in its aetiology, and parenteral high-dose thiamine is effective in prophylaxis and treatment. "
12/01/1983 - "The rapid improvement in the clinical manifestations of thiamine deficiency with thiamine supplementation is well known. "
03/01/1977 - "An associated thiamine deficiency was evidenced by decreased thiamine levels in the blood of one dog and in the food of another, and rapid remission of clinical signs in a dog given thiamine hydrochloride. "
07/01/2011 - "Evidence from experimental and clinical studies suggests that metabolism and clearance of thiamine is disturbed in diabetes leading to tissue-specific thiamine deficiency in the kidney and other sites of development of vascular complications. "

01/01/2014 - "Thiamine was administered for suspected shoshin beriberi; his hemodynamic status improved dramatically within the next six hours. "
10/13/2000 - "A cardiovascular beriberi syndrome was suspected and 100 mg of thiamine administered i.v. Within hours the clinical picture improved significantly. "
10/01/2012 - "Case of beriberi showing improved cerebral blood flow after thiamine treatment."
11/10/1994 - "Thiamine supplementation was given only perorally in the first patient, and a severe catabolic state in the other delayed the improvement in the beriberi. "
08/25/1984 - "Empirical treatment with thiamine proved to be a cure for the disorder, for it was acute pernicious or fulminating beriberi. "

11/01/2000 - "The patient's health status improved following thiamine administration, with complete and rapid regression of symptoms of congestive heart failure. "
05/12/2004 - "Evidence suggests that heart failure can be improved by the additional administration of Vitamin B1. "
08/01/1992 - "Right heart failure was improved after administering vitamin B1. "
01/01/2013 - "Using Ovid MEDLINE, PubMed, and Excepta Medica (Embase), we conducted a systematic review and metaanalysis of randomized, double-blind, placebo-controlled trials of thiamine supplementation in patients with congestive heart failure. "
03/01/2012 - "This study suggests that thiamine supplementation has beneficial effects on cardiac function in patients with diuretic drugs for symptomatic chronic heart failure. "

01/01/2015 - "Wernicke encephalopathy was suspected according to his symptoms, and thiamine administration dramatically improved his condition. "
05/01/2000 - "Failure of large oral doses of thiamine hydrochloride to provide an effective treatment for Wernicke's encephalopathy emphasizes the need for adequate and rapid replacement of depleted brain thiamine levels by repeated parenteral therapy in adequate doses."
01/01/2011 - "Timing of efficacy of thiamine in Wernicke's disease in alcoholics at risk."
03/01/1984 - "The Wernicke's encephalopathy responded well to the administration of thiamine. "
03/01/1995 - "The present study examined the cytopathological changes within diencephalon of a rat model of Wernicke's encephalopathy and determined whether administration of thiamine at various intervals after onset of neurological signs can arrest or reverse the cytopathological process. "

01/01/2013 - "The administration of large quantities of thiamine was effective in reversing the fatigue in MS, suggesting that the abnormalities in thiamine-dependent processes could be overcome by diffusion-mediated transport at supranormal thiamine concentrations. "
12/01/2013 - "The purpose of this study was to find the effect of endurance training and thiamine supplementation on anti-fatigue during the exercise. "
03/01/2014 - "As the administration of thiamine led to a partial or complete regression of the fatigue and related disorders, it is reasonable to infer that the administration of large quantities of thiamine restores thiamine-dependent processes. "
03/01/2014 - "Treatment with thiamine led to partial or complete regression of the fatigue within a few hours or days. "
12/01/2013 - "The effects of endurance training and thiamine supplementation on anti-fatigue during exercise."