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Tetrachlorvinphos (Rabon)
An organophosphate cholinesterase inhibitor that is used as an insecticide. It has low mammalian toxicity. (From Merck Index, 11th ed)
Also Known As:
Rabon
; Gardona; Stirofos; Phosphoric acid, 2-chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl ester, (Z)-
Networked:
6
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Organophosphorus Compounds: 300
Organophosphates: 1942
Tetrachlorvinphos: 6
desmethyltetrachlorvinphos
dimethylvinphos
Experts
1.
Cayir, Akin
: 1 article (12/2021)
2.
Cobanoglu, Hayal
: 1 article (12/2021)
Related Diseases
1.
Body Weight (Weight, Body)
01/01/1978 - "
The mean body weights of the treated rats and mice were generally lower than those of the matched controls; however, the mortality rate was affected adversely by tetrachlorvinphos only in the male rats.
"
06/01/1978 - "
Tetrachlorvinphos was added to the mineral mixture of medicated cattle (n = 13) at the rate of 1.6 mg/day/kg of body weight for a 29-week period beginning May 2, 1975.
"
01/01/1977 - "
Adding an emulsifiable concentrate formulation of stirofos directly to manure at a rate of approximately 45 ppm of wet manure completely controlled the larvae of house fly (Musca domestica L.) whereas feeding stirofos at a rate of 1.5 mg per kg of body weight daily reduced larval counts 82% in manure from forage-fed heifers and 63% in manure from concentrate-fed heifers.
"
2.
Chromosomal Instability (Chromosome Stability)
12/01/2021 - "
Furthermore, exposure to tetrachlorvinphos at concentrations of 50 µg/ml induced a significant increase in chromosomal instability level (p < 0.05).
"
12/01/2021 - "
Furthermore, our findings suggested that exposure to tetrachlorvinphos increased chromosomal instability that is a hallmark of many malignancies.
"
3.
Poisoning
10/01/1977 - "
[Diagnosis of gardona poisoning in chickens].
"
4.
Neoplasms (Cancer)
12/01/2021 - "
Furthermore, our findings suggested that exposure to tetrachlorvinphos increased chromosomal instability that is a hallmark of many malignancies.
"
5.
Hepatocellular Carcinoma (Hepatoma)
01/01/1978 - "
In female B6C3F1 mice, the incidence of neoplastic nodule of the liver was associated with treatment, and in male mice tetrachlorvinphos was carcinogenic, causing hepatocellular carcinoma of the liver.
"
Related Drugs and Biologics
1.
Minerals
2.
Manure
3.
Chlorpyrifos (Lorsban)