Triethylenephosphoramide (TEPA)

01/01/2015 - "These findings suggest that APRPG-TEPA-PCL/si-mTOR is useful for the treatment of PTEN-positive tumors."
01/01/2013 - "These results suggest that miR-92a-C/TEPA-PCL is promising for the treatment of tumors via the suppression of angiogenesis."
01/01/2015 - "In EMT6 xenograft mouse models, TEPA administration inhibited the tumor growth and increased mice survival. "
01/01/2011 - "These results indicate that mTOR knockdown using APRPG-TEPA-PCL/simTOR is likely to be an effective strategy for cancer siRNA therapy."
05/10/2014 - "For in vivo delivery of miR-499 to tumors via systemic injection, miR-499-C/TEPA-PCL were decorated with Ala-Pro-Arg-Pro-Gly (APRPG) peptide-conjugated polyethylene glycol (PEG) to prepare APRPG-PEG-modified lipoplexes carrying miR-499 (APRPG-miR-499). "

01/01/1969 - "On the other hand, tepa was found to be very effective in inducing lasting sterility throughout the 6 successive matings. "
06/01/1971 - "Sterility and semisterility in male progeny of male mice treated with the chemical mutagen TEPA."
08/01/1980 - "A single intratesticular injection of TEPA or Thio-TEPA induced a period of infertility lasting 1-2 months. "
01/01/1969 - "The probable reasons for the recovery from sterility of apholate-treated males and the more lasting sterility of tepa-treated males are discussed."
01/01/1969 - "They found that, in experiments in which treated males were mated once only, both apholate and tepa induced sterility lasting at least 48 days. "

01/01/2015 - "These results indicate that TEPA inhibits CoCl2-induced EMT most likely via HIF1-α-Snail/Twist signaling pathway, and copper depletion may be exploited as a therapeutic for breast cancer. "
11/01/2015 - "Transformation of alkylating regimen of thiotepa into tepa determines the disease progression through GSTP1 gene polymorphism for metastatic breast cancer patients receiving thiotepa containing salvage chemotherapy."

01/01/2013 - "The aim of this work was to study dynamics of new cases of hospital thromboembolism of pulmonary artery branches (TEPA) based on the registry data of Tomsk hospitals for 2003-2010 and to estimate applicability of recommendations of European Society of Cardiologists (2008) on diagnostics and treatment of TEPA. "
01/01/2011 - "The aim of this work was to evaluate the potential of radionuclide tomoventriculography (RTVG) for the study of the functional state of right ventricle (RV) in patients with thromboembolism of branches of the pulmonary artery (TEPA) or ventricular arrhythmias. "
01/01/2013 - "The number of new cases of submassive TEPA and TEPA of small branches with the fatal outcome decreased to 40.7 and 48% since 2007 while the incidence of lethal massive thromboembolism amounted to 68%. "
01/01/2005 - "Recurrent pulmonary artery thromboembolism (TEPA) prevailed in APS patients. "
01/01/2000 - "Pathologo-morphological and clinical records of 803 surgical patients have been analysed, in whom the thromboembolism of pulmonary artery (TEPA) was the only or the main cause of the death. "

01/01/2011 - "Our study was concerned with the role of ultrasound examination of the lower extremity veins to detect deep venous thrombosis and to evaluate complex prophylaxis of thromboembolism of pulmonary arteries (TEPA). "
01/01/2011 - "Up to 75% of the cases of venous thrombosis in the lower extremities are associated with latent TEPA and 80% of the cases of pulmonory embolism with asymptomatic venous thrombosis. "
01/01/2011 - "This condition is currently regarded as a continuum of thromboembolism of pulmonary artery (TEPA) and venous thromboses including superficial venous thromboses. "
03/01/2003 - "In 65 patients an acute venous thrombosis was complicated by thromboembolism of pulmonary artery (TEPA), 2 patients died before initiation of treatment. "
01/01/2005 - "Risk factors of the development of phlebothrombosis and thromboembolism of the pulmonary artery (TEPA) were estimated in 257 patients as associated both with the patient and the trauma. "