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Telangiectasis (Telangiectasia)

Permanent dilation of preexisting blood vessels (CAPILLARIES; ARTERIOLES; VENULES) creating small focal red lesions, most commonly in the skin or mucous membranes. It is characterized by the prominence of skin blood vessels, such as vascular spiders.
Also Known As:
Telangiectasia; Telangiectases; Spider Vein; Telangiectasias; Vein, Spider; Veins, Spider; Spider Veins
Networked: 2030 relevant articles (205 outcomes, 149 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Erythema
2. Rosacea (Acne Rosacea)
3. Epistaxis (Nosebleed)
4. Telangiectasis (Telangiectasia)
5. Hemangioma (Angioma)

Experts

1. Holz, Frank G: 25 articles (12/2022 - 01/2007)
2. Charbel Issa, Peter: 24 articles (12/2022 - 01/2007)
3. Yannuzzi, Lawrence A: 14 articles (01/2022 - 06/2005)
4. Spaide, Richard F: 14 articles (03/2021 - 05/2002)
5. Chew, Emily Y: 13 articles (01/2022 - 07/2010)
6. Friedlander, Martin: 13 articles (01/2022 - 03/2009)
7. Heeren, Tjebo F C: 13 articles (01/2022 - 05/2013)
8. Scholl, Hendrik P N: 12 articles (05/2013 - 01/2007)
9. Pauleikhoff, Daniel: 11 articles (01/2022 - 04/2010)
10. Bird, Alan C: 11 articles (01/2021 - 03/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Telangiectasis:
1. Bevacizumab (Avastin)FDA Link
2. NeodymiumIBA
3. Retinaldehyde (Retinal)IBA
03/01/2016 - "Specific morphologic alterations precede vascular alterations and functional deficits in macular telangiectasia type 2. The described alterations indicate a primarily degenerative process with a secondary retinal vascular phenotype, and may be helpful for early identification of patients and affected family members."
11/01/2005 - "Other findings included the presence of hyperreflectivity in the middle or inner retinal layers, suggesting retinal pigment epithelium proliferation and migration corresponding to the stellate foci of pigmentation in stage 4 and features of choroidal or subretinal neovascular membrane in stage 5. The optical coherence tomography findings in group 2A idiopathic juxtafoveolar telangiectasis were characteristic and may be helpful in making the diagnosis and defining, as far as possible, the anatomical staging."
11/07/2022 - "In this study, we present a unique case of a young female with known HHT and a series of retinal fundus images including optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) with macular telangiectasia-like lesions. "
01/01/2019 - "We present two generations of a single family with Ser384Phe mutation in the SPTLC2 gene located on chromosome 14q24 characterized by a typical HSAN-1c presentation, with additional findings upper motor neuron signs, early demyelinating features on nerve conduction studies, and type II juxtafoveal retinal telangiectasias also known as macular telangiectasias (MacTel II). "
02/01/2017 - "The use of OCTA for delineation of choroidal neovascular membranes, for the study of microvascular abnormalities in diabetic patients, to assess nonperfused areas in retinal occlusions and vascular changes in macular telangiectasia are some of the potential OCTA applications. "
4. Sclerosing Solutions (Sclerosing Agents)IBA
5. ArgonIBA
6. Polidocanol (Laureth)FDA Link
7. Ranibizumab (Lucentis)FDA Link
8. yttrium-aluminum-garnetIBA
9. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10. 1-phenyl-3,3-dimethyltriazene (PDT)IBA

Therapies and Procedures

1. Lasers (Laser)
2. Solid-State Lasers
3. Therapeutics
4. Dye Lasers
5. Sclerotherapy