Sinoatrial Nodal Reentry Tachycardia

Abnormally rapid heartbeats caused by reentry circuit in or around the SINOATRIAL NODE. It is characterized by sudden onset and offset episodes of tachycardia with a HEART RATE of 100-150 beats per minute. The P wave is identical to the sinus P wave but with a longer PR interval.

Also Known As:

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Tachycardia (Tachyarrhythmias)
2.	Atrioventricular Block
3.	Supraventricular Tachycardia
4.	Atrioventricular Nodal Reentry Tachycardia (AV Nodal Reentrant Tachycardia)
5.	Heart Diseases (Heart Disease)

Experts

1.	Chong, Daniel Thuan Tee: 1 article (03/2012)
2.	Malik, Amit Kumar: 1 article (03/2012)
3.	Teo, Wee Siong: 1 article (03/2012)
4.	Liew, Reginald: 1 article (03/2012)
5.	Ching, Chi Keong: 1 article (03/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Sinoatrial Nodal Reentry Tachycardia:

1.	Verapamil (Calan)FDA LinkGeneric 05/01/1985 - "Treatment of sinus node reentrant tachycardia with verapamil." 01/01/1985 - "Induction of sustained sinus node reentrant tachycardia was prevented by intravenous ouabain (0.01 mg/kg body weight) in two of two patients, by intravenous verapamil (10 mg) in two of two patients and by intravenous amiodarone (5 mg/kg body weight) in four of four patients. " 01/01/1985 - "It is concluded that sustained sinus node reentrant tachycardia, seen in 16.9% of the study patients with paroxysmal supraventricular tachycardia, is not as benign as previously believed; it is frequently associated with organic heart disease; it demonstrates wide variations in cycle length, unlike other forms of paroxysmal supraventricular tachycardia; it can masquerade as AV nodal reentrant tachycardia and paroxysmal atrial tachycardia with AV block on the surface electrocardiogram in 36% of patients; and it is responsive to intravenous administration of ouabain, verapamil or amiodarone."
2.	Ouabain (G Strophanthin)IBA 01/01/1985 - "Induction of sustained sinus node reentrant tachycardia was prevented by intravenous ouabain (0.01 mg/kg body weight) in two of two patients, by intravenous verapamil (10 mg) in two of two patients and by intravenous amiodarone (5 mg/kg body weight) in four of four patients. " 01/01/1985 - "It is concluded that sustained sinus node reentrant tachycardia, seen in 16.9% of the study patients with paroxysmal supraventricular tachycardia, is not as benign as previously believed; it is frequently associated with organic heart disease; it demonstrates wide variations in cycle length, unlike other forms of paroxysmal supraventricular tachycardia; it can masquerade as AV nodal reentrant tachycardia and paroxysmal atrial tachycardia with AV block on the surface electrocardiogram in 36% of patients; and it is responsive to intravenous administration of ouabain, verapamil or amiodarone."
3.	Amiodarone (Amiodarona)FDA LinkGeneric 01/01/1985 - "Induction of sustained sinus node reentrant tachycardia was prevented by intravenous ouabain (0.01 mg/kg body weight) in two of two patients, by intravenous verapamil (10 mg) in two of two patients and by intravenous amiodarone (5 mg/kg body weight) in four of four patients. " 01/01/1985 - "It is concluded that sustained sinus node reentrant tachycardia, seen in 16.9% of the study patients with paroxysmal supraventricular tachycardia, is not as benign as previously believed; it is frequently associated with organic heart disease; it demonstrates wide variations in cycle length, unlike other forms of paroxysmal supraventricular tachycardia; it can masquerade as AV nodal reentrant tachycardia and paroxysmal atrial tachycardia with AV block on the surface electrocardiogram in 36% of patients; and it is responsive to intravenous administration of ouabain, verapamil or amiodarone."
4.	AdenosineFDA LinkGeneric 11/01/1993 - "Adenosine causes prolongation of the atrial cycle length followed by termination of sinus node reentrant tachycardia." 07/01/1989 - "The effects of adenosine given during sinus node reentrant tachycardia were investigated in two patients. " 07/01/1989 - "The effects of adenosine on sinus node reentrant tachycardia." 06/01/1994 - "Adenosine terminated sinus node reentrant tachycardia in 6 of 6 patients and terminated atrial tachycardia due to triggered activity in the 1 patient in whom it was identified. " 07/01/1989 - "These effects of adenosine on sinus node reentrant tachycardia suggest that sinus nodal tissue (as opposed to perinodal atrial tissue) is involved in the tachycardia circuit and that these effects should be considered when adenosine is used as a diagnostic agent in narrow-complex tachycardia."
5.	Propranolol (Inderal)FDA LinkGeneric 01/01/1985 - "In contrast, intravenous propranolol (0.1 mg/kg body weight) did not affect induction of sustained sinus node reentrant tachycardia in two of two patients. "

Therapies and Procedures

1.	Catheters 03/01/2012 - "Ablation of sinus node reentrant tachycardia (SNRT) may be difficult with risk of sinus node injury by using conventional catheters. "