Atrioventricular Nodal Reentry Tachycardia (AV Nodal Reentrant Tachycardia)

Abnormally rapid heartbeats caused by reentry of atrial impulse into the dual (fast and slow) pathways of ATRIOVENTRICULAR NODE. The common type involves a blocked atrial impulse in the slow pathway which reenters the fast pathway in a retrograde direction and simultaneously conducts to the atria and the ventricles leading to rapid HEART RATE of 150-250 beats per minute.

Also Known As:

Networked: 237 relevant articles (27 outcomes, 27 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Supraventricular Tachycardia
2.	Tachycardia (Tachyarrhythmias)
3.	Wolff-Parkinson-White Syndrome (Wolf-Parkinson-White Syndrome)
4.	Reciprocating Tachycardia
5.	Ectopic Atrial Tachycardia

Experts

1.	Collins, Kathryn K: 7 articles (11/2012 - 05/2006)
2.	Van Hare, George F: 5 articles (06/2010 - 05/2006)
3.	Dubin, Anne M: 5 articles (06/2010 - 05/2006)
4.	Chiesa, Nancy A: 5 articles (06/2010 - 05/2006)
5.	Tonet, Joelci: 4 articles (10/2012 - 07/2010)
6.	Tuzcu, Volkan: 3 articles (06/2014 - 01/2013)
7.	Akdeniz, Celal: 3 articles (06/2014 - 01/2013)
8.	Drago, Fabrizio: 3 articles (04/2014 - 02/2008)
9.	De Sisti, Antonio: 3 articles (10/2012 - 07/2010)
10.	Avasarala, Kishor: 3 articles (06/2010 - 05/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Atrioventricular Nodal Reentry Tachycardia:

1.	Propafenone (Rythmol)FDA LinkGeneric 07/01/1994 - "In patients with atrioventricular nodal reentry tachycardia, propafenone is able to block conduction in the fast conducting pathway. " 07/01/1984 - "Effects of propafenone on induction and maintenance of atrioventricular nodal reentrant tachycardia." 03/01/2010 - "The aim of this prospective, non-randomized interventional study was to assess electrophysiological effects, efficacy and safety of intravenous propafenone in termination of atrioventricular nodal reentrant tachycardia (AVNRT) and orthodromic atrioventricular reentrant tachycardia (AVRT). " 03/01/2010 - "Electrophysiological effects, efficacy and safety of intravenous propafenone in termination of atrioventricular nodal reentrant tachycardia and atrioventricular reentrant tachycardia: a prospective non-randomized interventional study." 10/01/1985 - "The electrophysiologic effects of intravenous (i.v.) and oral propafenone were evaluated in 14 patients with Wolff-Parkinson-White syndrome and in 10 patients with atrioventricular (AV) nodal reentrant tachycardia. "
2.	Amiodarone (Amiodarona)FDA LinkGeneric 10/01/1983 - "This may also apply to atrioventricular nodal reentrant tachycardia, in which amiodarone is also extremely effective in preventing relapses. " 03/01/1996 - "Electrophysiologic effects and the efficacy of single-dose intravenous (i.v.) amiodarone were compared with those of long-term oral therapy in 9 patients of AV nodal reentrant tachycardia (AVNRT) utilising slow pathway (SP) for anterograde and fast pathway (FP) for retrograde conduction. " 03/01/1996 - "Comparison of electrophysiologic effects and efficacy of single-dose intravenous and long-term oral amiodarone therapy in patients with AV nodal reentrant tachycardia." 01/01/1985 - "It is concluded that sustained sinus node reentrant tachycardia, seen in 16.9% of the study patients with paroxysmal supraventricular tachycardia, is not as benign as previously believed; it is frequently associated with organic heart disease; it demonstrates wide variations in cycle length, unlike other forms of paroxysmal supraventricular tachycardia; it can masquerade as AV nodal reentrant tachycardia and paroxysmal atrial tachycardia with AV block on the surface electrocardiogram in 36% of patients; and it is responsive to intravenous administration of ouabain, verapamil or amiodarone." 03/01/2013 - "Diagnosis on electrocardiogram (ECG) was atrioventricular reentry tachycardia (AVRT) in 5, atrial ectopic tachycardia (AET) in 2, a combination of AVRT and atrioventricular nodal reentry tachycardia (AVNRT) in 1. All patients had failed trial of antiarrhythmic drugs prior to presentation: digoxin and propranolol in 7, amiodarone in 3, cardioversion in 1. Flecainide (80-130 mg/m(2) orally) resulted in termination of the tachycardia in all 8 patients. "
3.	AdenosineFDA LinkGeneric 01/01/2002 - "In this study, we sought to determine the effects of adenosine on the antegrade fast, antegrade slow, and retrograde fast pathway conduction in patients with AV nodal reentrant tachycardia (AVNRT). " 08/01/1998 - "Several studies have shown that the fast pathway is more responsive to adenosine than the slow pathway in patients with AV nodal reentrant tachycardia. " 05/01/2014 - "Adenosine sensitivity of retrograde fast pathway conduction in patients with slow-fast atrioventricular nodal reentrant tachycardia: a prospective study." 10/01/2009 - "Adenosine more frequently resulted in appearance of ventricular beats (15.4% vs 41.7%, P = 0.003), and this was more frequently observed in patients with atrioventricular nodal reentrant tachycardia. " 05/01/2007 - "Induction of atrioventricular nodal reentry tachycardia with intravenous adenosine."
4.	Anti-Arrhythmia AgentsIBA 10/01/1989 - "We performed transcatheter AV junction ablation with high frequency energy in four patients with AV nodal reentrant tachycardia where extensive trials of several antiarrhythmic drugs failed to prevent further recurrences of tachycardia. " 02/16/1989 - "We applied a new technique of catheter ablation to treat atrioventricular nodal reentrant tachycardia and preserve anterograde conduction, performing this procedure in 21 patients with repetitive episodes of tachycardia refractory to antiarrhythmic drugs. " 11/01/1989 - "Serial electrophysiological testing of multiple antiarrhythmic drugs was performed in 98 patients with paroxysmal supraventricular tachycardia (WPW syndrome 32, concealed WPW syndrome 46, atrioventricular nodal reentrant tachycardia 20). " 03/01/2000 - "But, it is very useful to analysis tachyarrhythmias and indicate antiarrhythmic drugs or catheter ablation for patients with Wolf-Parkinson-White(WPW) syndrome, AV nodal reentrant tachycardia, atrial tachycardia, atrial flutter, or ventricular tachycardia to cure the tachyarrhythmias." 03/01/2013 - "Diagnosis on electrocardiogram (ECG) was atrioventricular reentry tachycardia (AVRT) in 5, atrial ectopic tachycardia (AET) in 2, a combination of AVRT and atrioventricular nodal reentry tachycardia (AVNRT) in 1. All patients had failed trial of antiarrhythmic drugs prior to presentation: digoxin and propranolol in 7, amiodarone in 3, cardioversion in 1. Flecainide (80-130 mg/m(2) orally) resulted in termination of the tachycardia in all 8 patients. "
5.	EncainideIBA 09/01/1991 - "Encainide is an agent effective in atrioventricular and atrioventricular nodal reentrant tachycardia. " 12/20/1988 - "To prospectively determine the clinical efficacy and electrophysiologic effects of encainide in atrioventricular nodal reentrant tachycardia (AVNRT), 49 patients refractory to 2.7 +/- 1.5 previous antiarrhythmic drug trials underwent electrophysiologic study before and 47 did so after administration of oral encainide (75 to 240 mg/day). " 12/20/1988 - "Efficacy and electrophysiologic effects of encainide for atrioventricular nodal reentrant tachycardia." 09/01/1988 - "The present case report describes an unusual and marked prolongation of the Q-T interval with no Q-R-S interval prolongation in a patient who was treated with encainide for atrioventricular nodal reentrant tachycardia. " 07/01/1987 - "The third patient was not studied while receiving encainide, but spontaneous AV nodal reentrant tachycardia occurring multiple times daily was abolished. "
6.	Verapamil (Calan)FDA LinkGeneric 03/01/1999 - "Using measurements of QT/RR slopes with a computerized Holter system, QT interval dynamicity was evaluated in 19 patients with normal structural heart before and 2 months after oral treatment with verapamil prescribed for paroxysmal atrioventricular nodal reentrant tachycardia. " 01/18/1993 - "In a 42-year female with paroxysmal atrioventricular nodal reentrant tachycardia of the type I (slow/fast) verapamil did not prevent it. " 01/01/1988 - "Verapamil-mediated atrioventricular nodal reentrant tachycardia and the uncovering of dual-pathway AV nodal conduction." 09/01/1984 - "Effect of verapamil on retrograde conduction in atrioventricular nodal reentrant tachycardia." 09/01/1980 - "Verapamil in prophylaxis of paroxysmal atrioventricular nodal reentrant tachycardia."
7.	Adenosine Triphosphate (ATP)IBA 03/01/2000 - "We recently reported that administration of adenosine triphosphate (ATP) during sinus rhythm identifies dual AV nodal physiology (DAVNP) in 76% of patients with inducible sustained AV nodal reentrant tachycardia (AVNRT) at electrophysiologic (EP) study. " 12/01/2009 - "["ATP test" to assess the results of slow pathway ablation in patients with AV nodal reentrant tachycardia]." 12/01/2003 - "Reproducible induction of atrioventricular nodal reentrant tachycardia with adenosine triphosphate." 09/01/2003 - "Noninvasive diagnosis of dual AV nodal physiology in patients with AV nodal reentrant tachycardia by adenosine triphosphate test." 01/01/2003 - "Administration of adenosine triphosphate (ATP) in sinus rhythm identifies dual atrioventricular node physiology (DAVNP) in 75% of patients with inducible slow/fast AV nodal reentrant tachycardia (AVNRT). "
8.	Moricizine (Moracizine)FDA Link 09/01/1984 - "Electrophysiologic studies were performed in 11 patients with atrioventricular (AV) nodal reentrant tachycardia (SVT) before and after intravenous administration of 1.5 to 2 mg/kg ethmozin. " 11/15/1996 - "In three of the eight children (patients 3, 5 and 7), who presented with AV nodal reentrant tachycardia, automatic junctional ectopic tachycardia and atrial ectopic tachycardia, respectively, moricizine therapy was effective in restoring sinus rhythm and controlling the clinical tachycardia. "
9.	almokalantIBA 08/01/1995 - "In a Scandinavian multicenter, placebo-controlled trial, the antiarrhythmic efficacy of almokalant was investigated in patients with paroxysmal supraventricular tachycardia: 87 patients with mean age of 50 +/- 14 years (range 21-71 years), with reciprocating tachycardia due to either Wolff-Parkinson-White (WPW) syndrome (n = 58) or atrioventricular nodal reentry tachycardia (AVNRT) (n = 29) were studied with transesophageal atrial stimulation. " 08/01/1995 - "Effect of almokalant, a selective potassium channel blocker, on the termination and inducibility of paroxysmal supraventricular tachycardias: a study in patients with Wolff-Parkinson-White syndrome and atrioventricular nodal reentrant tachycardia. "
10.	Nadolol (Corgard)FDA LinkGeneric 02/01/1987 - "Intravenous nadolol is highly effective in sinus and AV nodal reentrant tachycardia, and a successful electrophysiologic response to it predicts efficacy of long-term oral nadolol therapy. " 08/31/1987 - "Intravenous nadolol prevented induction of SVT in 6 of 8 (75%) patients with atrioventricular nodal reentrant tachycardia, and oral nadolol prevented induction of SVT in 5 of 6 (83%) responders to intravenous nadolol. " 02/01/1987 - "Intravenous nadolol resulted in complete suppression of induced SVT in 78% of patients with sinus and atrioventricular nodal reentrant tachycardia and 11% of patients with atrioventricular (AV) reentrant tachycardia (p less than 0.001). "

Therapies and Procedures

1.	Catheters 05/15/2004 - "The ability of transvenous cryothermal catheter ablation to create reversible lesions (cryomapping) and to avoid catheter dislodgment (cryoadherence) has been shown to be safe and highly effective in elimination of atrioventricular nodal reentrant tachycardia. " 08/01/1990 - "Newer surgical and catheter techniques, together with a better understanding of the mechanisms underlying AV nodal reentrant tachycardia, may lead to improved efficacy and safety. " 05/01/2002 - "Catheter modulation of the AV node for the treatment of AV nodal reentrant tachycardia is effective and safe. " 03/01/2006 - "The magnetic guidance system appears to have similar, and possibly improved, clinical efficacy compared with conventional catheter navigation for the treatment of atrioventricular nodal reentrant tachycardia." 11/01/1994 - "The safety and efficacy of radiofrequency catheter modification of the atrioventricular node for atrioventricular nodal reentrant tachycardia in the pediatric population is described. "
2.	Cryosurgery 08/01/2009 - "The purpose of this study was to evaluate the safety and efficacy of cryoablation in a large series of patients with typical (slow-fast) atrioventricular nodal reentrant tachycardia (AVNRT). " 08/01/2006 - "This study was designed to assess the efficacy of event recording in evaluating long-term success in patients treated for atrioventricular nodal reentrant tachycardia (AVNRT) or right posteroseptally located accessory pathways (RPS) either by radiofrequency (RF) or by cryoablation (CA). " 05/01/2013 - "Cryoablation of atrioventricular nodal reentrant tachycardia in children and adolescents: improved long-term outcomes with increasing experience." 12/28/1991 - "AV nodal reentrant tachycardia can be cured using direct AV nodal dissection (or perinodal cryoablation). " 12/05/1989 - "AV nodal reentrant tachycardia can be cured using direct AV nodal dissection (or perinodal cryoablation). "
3.	Ablation Techniques 06/01/1993 - "The aim of our study was to evaluate how frequently the recording of peculiar slow potentials was possible in patients with atrioventricular nodal reentrant tachycardia, and to assess short-and long-term efficacy of an ablation technique involving the use of these potentials as electrophysiologic markers. " 04/01/1999 - "Although a variety of ablation techniques have been developed in the treatment of atrioventricular nodal reentrant tachycardia (AVNRT), there have been few reports discussing the location of the optimal target site. " 01/01/2003 - "Percutaneous catheter cryothermal ablation of atrioventricular nodal reentrant tachycardia: efficacy and safety of a new ablation technique." 08/01/1992 - "Since patients with paroxysmal supraventricular tachycardias (WPW syndrome and AV nodal reentrant tachycardia) can be cured by transvenous ablation techniques, EPS is indicating in this setting in all symptomatic patients for the diagnosis and the treatment of the given arrhythmia. "
4.	Lasers (Laser) 03/01/1997 - "Laser catheter coagulation of atrial myocardium for ablation of atrioventricular nodal reentrant tachycardia. " 08/01/1994 - "Two impacts of 30 s each (power 30 W and irradiated spot diameter 2.0-2.5 mm), applied via a novel laser catheter system, abolished both AF and AV nodal reentrant tachycardia. " 08/01/1994 - "This report describes an adolescent with refractory atrial flutter (AF) and atrioventricular (AV) nodal reentrant tachycardia who was cured by Nd: YAG, 1064 nm, laser application. " 08/01/1994 - "Laser catheter ablation of atrial flutter and of atrioventricular nodal reentrant tachycardia in a single session." 03/01/1997 - "A new technique for ablation of atrioventricular nodal reentrant tachycardia, using catheter-directed continuous wave Nd-YAG laser light, 1064 nm, via a novel pin-electrode laser catheter, was applied in 10 patients aged 15-63 years (mean 43 years). "
5.	Heart Transplantation (Grafting, Heart) 09/01/2015 - "[Successful ablation of an atrioventricular nodal reentrant tachycardia ablation 2 years after orthotopic heart transplantation]." 04/01/2006 - "Radiofrequency catheter ablation of atrioventricular nodal reentrant tachycardia in a patient with orthotopic heart transplantation by bicaval anastomosis." 10/01/1999 - "Radiofrequency catheter ablation of atrioventricular nodal reentrant tachycardia after orthotopic heart transplantation." 03/01/1998 - "Case report: radiofrequency catheter ablation of atrioventricular nodal reentrant tachycardia in a patient with heart transplantation." 02/01/1994 - "The present study examined histological changes induced by catheter guided radiofrequency current in a patient with AV nodal reentrant tachycardia who underwent cardiac transplantation 1 week after ablation of the slow pathway. "