Synovial Cyst

Non-neoplastic tumor-like lesions at joints, developed from the SYNOVIAL MEMBRANE of a joint through the JOINT CAPSULE into the periarticular tissues. They are filled with SYNOVIAL FLUID with a smooth and translucent appearance. A synovial cyst can develop from any joint, but most commonly at the back of the knee, where it is known as POPLITEAL CYST.

Also Known As:

Networked: 96 relevant articles (9 outcomes, 7 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Cysts
2.	Pain (Aches)
3.	Pathologic Constriction (Stenosis)
4.	Arthritis (Polyarthritis)
5.	Tendinopathy (Tendonitis)

Experts

1.	Epstein, Nancy E: 6 articles (01/2015 - 05/2004)
2.	Bydon, Ali: 4 articles (12/2014 - 05/2010)
3.	Gokaslan, Ziya L: 3 articles (12/2014 - 05/2010)
4.	Bydon, Mohamad: 3 articles (12/2014 - 09/2010)
5.	Witham, Timothy F: 3 articles (12/2014 - 05/2010)
6.	Wolinsky, Jean-Paul: 2 articles (02/2013 - 05/2010)
7.	Sandhu, Faheem A: 2 articles (11/2012 - 01/2004)
8.	Palmer, Sylvain: 2 articles (01/2012 - 01/2004)
9.	Parker, Scott L: 2 articles (09/2010 - 05/2010)
10.	McGirt, Matthew J: 2 articles (09/2010 - 05/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Synovial Cyst:

1.	Adrenal Cortex Hormones (Corticosteroids)IBA 09/01/2011 - "Described procedures are synovial biopsies, intra-articular injections of corticosteroids, radiation synovectomy and synovial cysts drainage procedures. " 11/01/2010 - "Injecting corticoids is useful in the treatment of synovial cysts, Baker's cyst, tendinitis, and non-infective arthritis. "
2.	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 11/01/2008 - "Aspiration and triamcinolone acetonide injection of wrist synovial cysts is an effective and safe treatment that may be considered as first-line treatment in the pediatric population if there is no resolution after 1 year of observation." 11/01/2008 - "Twenty-one records of pediatric patients with synovial cyst on the wrist treated with aspiration and triamcinolone acetonide injection were selected for analysis of their outcomes. " 11/01/2008 - "The aim of this case series report is to assess the effectiveness of aspiration and injection of triamcinolone acetonide for treatment of wrist synovial cysts in children. " 11/01/2008 - "Aspiration and triamcinolone acetonide injection of wrist synovial cysts in children."
3.	tebufenozide (Mimic)IBA 11/01/2012 - "Synovial cysts of the lumbar spine result from degeneration of the facet capsule and often mimic symptoms commonly seen with herniated intervertebral discs. " 11/01/1995 - "Intraspinal synovial cyst can mimic the clinical pattern of NHP. " 01/01/1990 - "Synovial cysts raise no diagnostic problems, unless they mimic an episode of phlebitis; echotomography has now become essential for diagnosis. " 01/01/2012 - "Being rare in foot and ankle, the unusual presentation of this lesion may sometimes mimic other lesions like lipoma, synovial sarcoma, malignant fibrous histiocytoma, synovial cyst and ganglion. " 08/01/1980 - "When synovial cysts occur as mass lesions they may mimic popliteal aneurysms or hematomas, adenopathy, tumors or even inguinal hernias. "
4.	Polyethylene (Polythene)IBA 01/01/2003 - "Presentation of gamma-irradiated-in-air polyethylene wear in the form of a synovial cyst." 01/01/2012 - "There are several well-described causes of a painful mass following total hip arthroplasty including polyethylene and metal wear debris, infection, expanding hematoma, dislocation, and synovial cysts. "
5.	Durapatite (Hydroxylapatite)IBA 01/01/2005 - "Migration of hydroxyapatite granules from uncovered portions of hydroxyapatite-coated cups may be a source of third-body wear and could accelerate synovial cyst formation." 01/01/2005 - "We present a case of a compressive intrapelvic synovial cyst 3 years after a total hip replacement with a hydroxyapatite-coated acetabular component. " 11/01/1994 - "Arthritides and enthesopathies such as rheumatoid arthritis, ankylosing spondylitis, synovial cysts of the facet joint, calcium pyrophosphate dihydrate deposition or hydroxyapatite deposition, and ossification of the posterior longitudinal ligament or ligamentum flavum may lead to narrowing of the spinal canal. "
6.	GadoliniumIBA 10/01/1993 - "Synovial cyst of the upper cervical spine: MRI with gadolinium." 07/01/1991 - "Five intraspinal synovial cysts in four patients were evaluated with noncontrast magnetic resonance imaging and magnetic resonance imaging with the contrast agent gadolinium diethylenetriaminepentaacetic acid. "
7.	Calcium PyrophosphateIBA 08/01/2012 - "We report on a 69-year-old woman with 2-level symptomatic synovial cysts of the facet joints caused by calcium pyrophosphate dihydrate crystal deposition. " 10/01/2002 - "A case of bilateral symptomatic facet joint synovial cysts arising in association with calcium pyrophosphate deposition disease is reported. " 10/01/2002 - "Bilateral symptomatic synovial cysts of the lumbar spine caused by calcium pyrophosphate deposition disease: a case report."
8.	Gadolinium DTPA (Magnevist)FDA Link 08/01/1991 - "MR of intraspinal synovial cyst: rim enhancement with gadopentetate dimeglumine."
9.	Antirheumatic Agents (DMARD)IBA 03/01/1998 - "The synovial cysts and arthralgia failed to respond to any of the disease modifying anti-rheumatic drugs (DMARDs) prescribed. "
10.	Etodolac (Lodine)FDA LinkGeneric 03/01/1989 - "Case studies of hindlimbs from normal, adjuvant arthritic, and etodolac-treated arthritic rats demonstrated the association of disease severity with inflammation, chondromalacia, replacement of adipose bone marrow with a fibroid marrow, osteoclastic bone resorption, synovial cysts, and pannus formation within the joints. "

Therapies and Procedures

1.	Decompression 01/01/2011 - "Surgical resection and decompression of the neural structures can be an effective treatment for symptomatic atlantoaxial synovial cysts." 12/01/2014 - "This study was undertaken to compare surgical outcomes between patients with atlantoaxial versus subaxial cervical synovial cysts (CSCs) and to compare outcomes between patients who underwent decompression alone versus decompression and fusion for the treatment of CSCs. " 01/01/2010 - "In this study, we present a case of a very rare and large suprapatellar synovial cyst of the knee, which was successfully treated with an arthroscopic intra-articular decompression. " 09/01/2015 - "Aware of the limited numbers, we suggest rather leaving remnants of an attached synovial cyst behind after a sufficient decompression than risking dural tears and surgery-related complications. " 05/01/2013 - "The authors previously reported anterior decompression of C1-2 synovial cysts and subsequent posterior fusion in a large series. "
2.	Laminectomy 03/01/2010 - "Hemilaminectomy or laminectomy with medial facetectomy without fusion might serve as an effective and safe management strategy to treat lumbar hemorrhagic juxtrafacet synovial cysts." 08/01/2015 - "Only six cases of symptomatic C5-C6 synovial cysts have been reported in the literature; the condition is usually treated with decompressive laminectomy. " 11/01/2012 - "The authors report 2 cases of a minimally invasive synovial cyst resection via a contralateral laminotomy. " 02/01/2012 - "Laminectomy and resection of the ligament flavum is a risk factor for the subsequent formation of a synovial cyst. " 02/01/2012 - "10 instances of post-laminectomy synovial cyst occurred in only the lumbar spine. "
3.	Injections 02/01/1999 - "One-third of patients with symptomatic lumbar facet joint synovial cysts had long-lasting acceptable benefit from facet joint steroid injections in this study. " 02/01/1999 - "To study the results of facet joint intraarticular steroid injections in patients with symptomatic lumbar facet joint synovial cysts. " 01/01/2013 - "CESIs, SNRBs, facet injections, and synovial cyst aspirations are the most frequently performed injections. " 02/01/2005 - "Partial arthrograms revealed 25 patients (9.0%) with synovial cysts (L3-4, n = 3; L4-5, n = 14; L5-S1, n = 8); 23 of these patients (92.0%) had a good response to the injections. " 10/01/2001 - "Clinical outcome and imaging findings were retrospectively studied in 12 patients (four men, eight women) aged 45-79 years (mean, 60 years) with a symptomatic lumbar facet joint synovial cyst treated with percutaneous steroid injections. "
4.	Spinal Manipulation 03/01/2012 - "Lumbar synovial cyst and stenosis-generated low back and radicular pain was 80% relieved in a 75-year-old man following Cox flexion distraction spinal manipulation." 03/01/2012 - "The purpose of this study is to report the findings resulting from chiropractic care using flexion distraction spinal manipulation for a patient with low back and radicular pain due to spinal stenosis caused by a synovial cyst. "
5.	Surgical Decompression 08/01/1996 - "Appropriate neuroradiological assessment is required in patients with suspected cervico-medullary compression, and symptomatic periodontoid synovial cysts may respond well to transoral surgical decompression." 01/01/2012 - "After a thorough review of the literature, it appears that the treatment with the best outcome for patients with synovial cysts is cyst removal utilizing surgical decompression; the need for attendant fusion remains unsettled. " 09/01/2012 - "Specifically, in the setting of acute cauda equina syndrome secondary to a lumbar synovial cyst, urgent surgical decompression has led to resolution of neurologic symptoms in most reported cases. " 07/01/2005 - "The patient had developed an epidural hematoma, secondary to rupture of a synovial cyst, documented at surgical decompression. "