Sympathomimetics (Sympathomimetic Amines)

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.

Also Known As:

Networked: 540 relevant articles (32 outcomes, 27 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Check, J H: 20 articles (01/2015 - 01/2006)
2.	Cohen, R: 9 articles (01/2014 - 01/2010)
3.	Katsoff, B: 4 articles (01/2014 - 01/2013)
4.	Parada, C A: 3 articles (09/2014 - 10/2012)
5.	Tambeli, C H: 3 articles (09/2014 - 10/2012)
6.	Boimel, P: 3 articles (01/2008 - 01/2007)
7.	Katsoff, D: 3 articles (01/2008 - 01/2006)
8.	Levine, Michael: 2 articles (06/2015 - 04/2013)
9.	Bray, George A: 2 articles (08/2014 - 04/2014)
10.	Randall, R Lor: 2 articles (10/2013 - 02/2006)

Related Diseases

1.	Asthma (Bronchial Asthma) 06/01/1994 - "The asthma symptom scores were low as well as the use of concomitant inhaled sympathomimetics which indicates good and equal efficacy of the preparations. " 01/01/2015 - "Sympathomimetic drugs are the mainstay of treatment for asthma patients. " 12/01/1995 - "Asthma protocol therapy, based primarily upon aggressive use of sympathomimetics in association with serial monitoring of key indices of improvement, provides prompt and efficient relief for acute exacerbations of asthma. " 02/21/1987 - "The circumstances surrounding the deaths of 75 asthmatic patients who had been prescribed a domiciliary nebuliser driven by an air compressor pump for administration of high dose beta sympathomimetic drugs were investigated as part of the New Zealand national asthma mortality study. " 03/01/1971 - "Studies on the pulmonary physiological effect of sympathomimetic amines in bronchial asthma."
2.	Pain (Aches) 01/01/2015 - "In addition, with other pain symptoms, this can be effectively treated with sympathomimetic amines." 01/01/2008 - "It is not clear if the improvement in pain is related to a decrease in fluid retention or a direct effect of the sympathomimetic amines on the sympathetic nervous system. " 01/01/2013 - "Temporary cessation resulted in prompt return of symptoms, but resumption of sympathomimetic amines again allowed good relief of bladder pain and related symptoms. " 10/01/2012 - "Temporomandibular joint (TMJ) receives rich sympathetic innervations that may contribute to TMJ pain through the local release of sympathomimetic amines. " 01/01/2010 - "Similar to other gastrointestinal pain syndromes and pain in other areas, e.g., pelvis, bladder, head and joints, treatment with sympathomimetic amines results in dramatic improvement."
3.	Heart Failure 09/11/2000 - "Use of sympathomimetic drugs leads to increased risk of hospitalization for arrhythmias in patients with congestive heart failure." 10/01/1997 - "All patients were in New York Heart Association (NYHA) functional class III to IV and required intravenous administration of sympathomimetic amines, in addition to standard heart failure treatment procedures. " 09/01/1990 - "Sympathomimetic agents are of limited use in patients with severe cardiac failure partly because of the down regulation of the myocardial beta-receptors. " 04/01/1990 - "Sympathomimetic agents are still used in patients with heart failure to augment cardiac contractility, but tachyphylaxis limits their long-term usefulness, and they may actually cause further myocardial damage. " 05/01/1989 - "The action of sympathomimetic amines may therefore be altered in patients with congestive heart failure."
4.	Premature Obstetric Labor (Premature Labor) 05/01/2001 - "The efficacy of preventive treatment by oral or subcutaneous administration of beta-sympathomimetics has also been assessed: a meta-analysis and 2 large randomized placebo-controlled trials have showed that oral maintenance treatment offers no advantages over placebo during the latency phase or for the recurrence rate of preterm labor and the rate of preterm delivery. " 05/01/2001 - " the 10 acceptable placebo-controlled trials, seven, including the largest (the Canadian Preterm Labor Investigators' Group, with 708 women), found that beta-sympathomimetics were not better than placebo in prolonging pregnancy or reducing neonatal morbidity. " 11/01/1991 - "Treatment of preterm labor with beta-sympathomimetics has been questioned because of the many maternal and fetal complications associated with its use. " 12/01/1987 - "Beta-sympathomimetic agents are used extensively in obstetrics to inhibit premature labor. " 10/01/1985 - "Beta sympathomimetic drugs are used clinically to inhibit premature labor. "
5.	Hyperalgesia 12/01/2006 - "The findings that local sympathomimetic amines contribute to the inflammatory TMJ hyperalgesia by activating beta(2)-adrenoceptors may be relevant to clinical TMJ inflammatory pain states less sensitive to nonsteroidal anti-inflammatory drugs." 10/01/2002 - "These data suggest that CINC-1, released at sites of inflammation, mediates inflammatory hyperalgesia in rats via release of sympathomimetic amines." 04/01/2013 - "We have demonstrated that the activation of P2X3 receptor on peripheral afferent neurons is critical to development of inflammatory hyperalgesia in peripheral tissue, although pharmacological administration of prostaglandin E(2) or sympathomimetic amines is enough to sensitize primary afferent neurons by acting directly in neuronal receptors. " 03/17/1987 - "These antagonists also abolished the rat paw hyperalgesia induced by several sympathomimetic amines as well as that induced by a selective DA-1 agonist, SKF 38393. " 01/01/2014 - "The sympathetic neural hyperalgesia/edema syndrome, a common cause of female pelvic pain, manifesting as a pseudopheochromocytoma with marked clinical improvement with sympathomimetic amines."

Related Drugs and Biologics

1.	Sympathomimetics (Sympathomimetic Amines)
2.	Carbachol (Carbastat)
3.	Adrenal Cortex Hormones (Corticosteroids)
4.	Histamine Antagonists (Antihistamines)
5.	Albuterol (Salbutamol)
6.	Diuretics
7.	Aerosols
8.	Methacholine Chloride (Methacholine)
9.	Antiemetics
10.	Narcotics (Narcotic Analgesics)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Hemoperfusion
3.	Tocolysis
4.	Denervation
5.	Resuscitation