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Sulfisoxazole (Sulfafurazole)

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A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.

Also Known As:

Sulfafurazole; Gantrisin; FNA Brand of Sulfisoxazole; Gantrisin Pediatric; Neoxazoi; Roche Brand of Sulfisoxazole; Roche Brand of Sulfisoxazole Acetate; Roche Brand of Sulfisoxazole Diolamine; Sulfadimethyloxazole; Sulfafurazol FNA; Sulfasoxizole; Sulfisoxazole Diolamine; Sulfisoxazole, Ammonium Salt; Sulfisoxazole, Monolithium Salt; Sulfisoxazole, Monosodium Salt; Sulfisoxazole, Monosodium, Monomesylate Salt; Sulfisoxazole, Triammonium Salt; TL-azole; V-Sul; Vangard Brand of Sulfisoxazole; Zenith Brand of Sulfisoxazole; Ammonium Salt Sulfisoxazole; Diolamine, Sulfisoxazole; Monolithium Salt Sulfisoxazole; Monosodium Salt Sulfisoxazole; Pediatric, Gantrisin; Sulfisoxazole Roche Brand; TL azole; Triammonium Salt Sulfisoxazole; V Sul; Benzenesulfonamide, 4-amino-N-(3,4-dimethyl-5-isoxazolyl)-

Networked: 182 relevant articles (11 outcomes, 18 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Ahlfors, C E: 2 articles (12/2001 - 10/2000)
2.	Deshpande, Sharad S: 1 article (04/2014)
3.	Thyagarajan, Baskaran: 1 article (04/2014)
4.	Gulati, Anil: 1 article (01/2011)
5.	Andurkar, Shridhar V: 1 article (01/2011)
6.	Pérez-López, M: 1 article (10/2009)
7.	Muñoz-Negrete, F J: 1 article (10/2009)
8.	Rebolleda, G: 1 article (10/2009)
9.	Won Kim, H R: 1 article (10/2009)
10.	Takebayashi, Satoshi: 1 article (09/2008)

Related Diseases

1.	Urinary Tract Infections (Urinary Tract Infection) 08/15/1955 - "A comparison of therapeutic efficacy between a triple sulfonamide mixture and gantrisin in urinary tract infections." 11/01/1981 - "In conclusion, the study results suggest that the inclusion of a 2-g loading dose of sulfisoxazole in the treatment of this sample of acute, uncomplicated urinary tract infections did not offer any therapeutic benefit." 11/01/1981 - "Comparative trial of two sulfisoxazole regimens in acute urinary tract infection." 10/01/1985 - "The patients received sulfisoxazole prophylactically for urinary tract infection commencing 7 days postoperatively. " 09/29/1984 - "[The treatment of urinary tract infections with sulfafurazole; a single dose or a 7-day course?]."
2.	Otitis Media 10/01/1986 - "The attack rate (episodes of otitis media per 2-month period) was 0.78 before sulfisoxazole, 0.72 while receiving sulfisoxazole, and 0.56 after sulfisoxazole prophylaxis. " 10/01/1986 - "Acute otitis media occurred in eight of 14 (51%) children while receiving sulfisoxazole, and in two of five (40%) children while receiving no prophylaxis. " 06/01/1985 - "During the sulfisoxazole therapy, seven patients (22%) had nine episodes of acute otitis media (AOM) while 20 patients (63%) receiving placebo had 36 episodes of AOM (P = .001). " 07/01/1983 - "In conclusion the use of sulfisoxazole and pneumococcal vaccine appears efficacious for management of asthmatic children with recurrent otitis media." 07/01/1983 - "There was a mean yearly reduction in otitis media of 75% in the sulfisoxazole group, 38% in the pneumococcal vaccine group and 90% in the group treated with both agents. "
3.	Otitis Media with Effusion 06/01/1985 - "Sulfisoxazole therefore appears effective in preventing recurrent symptomatic AOM but not in reducing the frequency of persistent otitis media with effusion. " 06/01/1985 - "Otitis media with effusion persisting for more than five weeks was observed in ten children (31%) during sulfisoxazole therapy and in 14 children (44%) during the placebo period (P greater than .975). " 06/01/1985 - "Sulfisoxazole prophylaxis of middle ear effusion and recurrent acute otitis media." 05/01/1994 - "Secondary antimicrobial prophylaxis with amoxicillin or sulfisoxazole reduces the frequency of recurrent AOM by about 50%, but it does not appear to reduce the duration of otitis media with effusion (OME). " 10/01/1986 - "Erythromycin antimicrobial prophylaxis for children with recurrent otitis media was superior to no prophylaxis and to sulfisoxazole prophylaxis in this study of patients with recurrent otitis media without persistent middle ear effusion."
4.	Infection 01/10/1953 - "[Clinical study of gantrisin in therapy of infections of urinary tract]." 11/01/1949 - "Gantrisin; an in vivo and in vitro study in urinary infections." 11/15/2007 - "Furthermore, subconjunctival application of sulfisoxazole could be more efficient for treatment of intraocular infections due to higher absorption of drug and longer remaining time in the eye compared to topical application." 11/15/2007 - "These results indicate that sulfisoxazole may not be potent enough to treat intraocular infections caused by bacteria when applied either subconjunctivally or topically at a dose of 2 mg/eye. " 05/01/1981 - "Concommitant administration of sulfisoxazole suspension may have reduced the likelihood of activation of a quiescent infection of the middle ear. "
5.	Sinusitis 05/01/1999 - "This study compares the effectiveness of 10, 15, and 20 days of ceftibuten therapy with 14 days of erythromycin-sulfisoxazole therapy in treating acute sinusitis. " 05/01/1999 - "The results indicate that both treatment regimens are effective in treating acute sinusitis (96% clinical response for erythromycin-sulfisoxazole vs 92% for a 10- or 15-day course of ceftibuten vs 100% for a 20-day course of ceftibuten). "

Related Drugs and Biologics

1.	Erythromycin (Erycette)
2.	Amoxicillin (Wymox)
3.	Cefaclor (Ceclor)
4.	ceftibuten (Cedex)
5.	Chloramphenicol (Chloromycetin)
6.	Anti-Bacterial Agents (Antibiotics)
7.	Tetracycline (Achromycin)
8.	Erythromycin Ethylsuccinate (E-Mycin E)
9.	Cephalexin (Cefalexin)
10.	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)

Related Therapies and Procedures

1.	Chemoprevention
2.	Drug Therapy (Chemotherapy)
3.	Day Care (Partial Hospitalization)
4.	Analgesia
5.	Transplants (Transplant)