Sugar Alcohols

Polyhydric alcohols having no more than one hydroxy group attached to each carbon atom. They are formed by the reduction of the carbonyl group of a sugar to a hydroxyl group.(From Dorland, 28th ed)

Also Known As:

Networked: 49 relevant articles (1 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Magan, N: 2 articles (05/2004 - 08/2001)
2.	Yu, Guoyong: 1 article (08/2014)
3.	Li, Jing: 1 article (08/2014)
4.	Fan, Junfeng: 1 article (08/2014)
5.	Almståhl, Annica: 1 article (07/2013)
6.	Lingström, Peter: 1 article (07/2013)
7.	Eliasson, Lars: 1 article (07/2013)
8.	Carlén, Anette: 1 article (07/2013)
9.	Chassard, C: 1 article (09/2012)
10.	Payne, A N: 1 article (09/2012)

Related Diseases

1.	Cardiovascular Diseases (Cardiovascular Disease) 08/08/2014 - "Alditols and monosaccharides from sorghum vinegar inhibit multiple steps in the platelet aggregation pathway, and may be beneficial for the treatment of cardiovascular diseases."
2.	Cataract (Cataracts) 01/01/1988 - "Study of experimental cataract produced by sugar alcohols in the organ-cultured mammalian ocular lens." 01/01/1993 - "Sugar alcohols in the lens epithelium of age-related cataract." 01/01/1988 - "It is proposed that the observed lens opacities are due to the presence of sugar alcohols in the culture medium and not to hyperosmolar shock." 05/01/1991 - "The osmotic nature of these cataracts and the observation that their formation can be reduced in a dose-dependent manner by aldose reductase inhibitors are consistent with the concept that the aldose-reductase catalyzed formation of polar sugar alcohols (polyols) initiates sugar cataract formation in the dog." 01/01/1976 - "Sugar alcohols in the pathogenesis of galactose and diabetic cataracts."
3.	Diarrhea 07/01/2004 - "The tendencies for diarrhea, faster digesta transit and reduced body fat induced by the fermentable materials in the cecectomized rat have good relevance to the parallel effects of fermentable materials in humans, suggesting the possibility of using the cecectomized rat as a model to study some of the physiological effects of sugar alcohols in humans." 05/01/2009 - "Diarrhea started at a dose of 4.95 g/kg of rare sugar alcohols. " 07/01/2004 - "Diarrhea, faster transit times and shorter retention times of digesta were noted in the cecectomized rats fed sugar alcohols, while the inverse results were observed in the normal rats fed similar diets. " 05/01/2009 - "To investigate the laxative effect of rare sugar alcohols, the study was designed to observe the diarrhea that occurred after oral administration of these sugar alcohols in mice. " 02/01/2007 - "Non-digestible and/or non-absorbable sugar alcohols and oligosaccharides with beneficial health effects inevitably cause overt diarrhea. "
4.	Dehydration (Water Stress) 11/01/2004 - "Blastospores produced under different water-stress levels were subjected to hypo-osmotic and iso-osmotic washing treatments before quantification of endogenous sugar alcohols (polyols) and germinability studies. " 11/01/2004 - "Impact of water-stress and washing treatments on production, synthesis and retention of endogenous sugar alcohols and germinability of Metarhizium anisopliae blastospores." 07/07/2010 - "These findings indicate that the aquaglyceroporin selectivity filter does not discriminate sugar alcohols based on their length, and that the extra energy cost of dehydration of larger sugar alcohols, upon entering the pore, is compensated for by additional hydrogen-bond interactions within the aquaglyceroporin pore." 05/01/2004 - "Impact of osmotic and matric water stress on germination, growth, mycelial water potentials and endogenous accumulation of sugars and sugar alcohols in Fusarium graminearum." 08/01/2001 - "Biomass from liquid cultures responded to water-stress by accumulating increased concentrations of endogenous sugar alcohols (polyols), particularly glycerol. "
5.	Neuroblastoma 01/01/2003 - "In this study, we compared various monosaccharides, disaccharides, nutritive/non-nutritive sugar alcohols, glycolytic and gluconeogenic metabolic intermediates for their cytoprotection against MPP+ in murine brain neuroblastoma cells. "

Related Drugs and Biologics

1.	Monosaccharides
2.	Acetic Acid (Vinegar)
3.	Galactose (Galactopyranose)
4.	Disaccharides
5.	Sorbitol (Yal)
6.	Mannitol (Osmitrol)
7.	Inositol (Myoinositol)
8.	Galactitol
9.	Carbohydrates
10.	Glycoproteins (Glycoprotein)

Related Therapies and Procedures

1.	Lenses
2.	Oral Administration
3.	Cataract Extraction