Sucrase-Isomaltase Complex

An enzyme complex found in the brush border membranes of the small intestine. It is believed to be an enzyme complex with different catalytic sites. Its absence is manifested by an inherited disease called sucrase-isomaltase deficiency.

Also Known As:

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Abe, Tatsuya: 1 article (06/2013)
2.	Hata, Keishi: 1 article (06/2013)
3.	Iwashita, Jun: 1 article (06/2013)
4.	Kikuchi, Tsugio: 1 article (06/2013)
5.	Ohtomo, Masanobu: 1 article (06/2013)
6.	Takashima, Akiko: 1 article (06/2013)
7.	Alfalah, Marwan: 1 article (05/2006)
8.	Castelletti, Deborah: 1 article (05/2006)
9.	Keiser, Markus: 1 article (05/2006)
10.	Naim, Hassan Y: 1 article (05/2006)

Related Diseases

1.	congenital Sucrase-isomaltase deficiency 01/01/1975 - "In the patients with sucrase-isomaltase deficiency there was a complete absence of active sucrase-isomaltase complex. " 11/20/1974 - "Absence of brush border sucrase-isomaltase complex in congenital sucrose intolerance." 05/19/2006 - "Here, we describe the molecular basis of a novel phenotype of congenital sucrase-isomaltase deficiency (CSID), a disaccharide malabsorption disorder of the human intestine in which several structural features and functional capacities of the brush-border enzyme complex sucrase-isomaltase (SI) are affected. "
2.	Insulin Resistance 01/04/1999 - "Disordered expression of the sucrase-isomaltase complex in the small intestine in Otsuka Long-Evans tokushima fatty rats, a model of non-insulin-dependent diabetes mellitus with insulin resistance."
3.	Type 2 Diabetes Mellitus (MODY) 01/04/1999 - "Disordered expression of the sucrase-isomaltase complex in the small intestine in Otsuka Long-Evans tokushima fatty rats, a model of non-insulin-dependent diabetes mellitus with insulin resistance."
4.	Cystic Fibrosis (Mucoviscidosis) 01/01/1985 - "The intestinal microvillar enzyme complex sucrase-isomaltase has been studied in cystic fibrosis and control ileum. "
5.	Colonic Neoplasms (Colon Cancer) 06/01/2013 - "Real-time RT-PCR demonstrated that RBWE up-regulated the expression of MUC2 and sucrase-isomaltase complex (a differentiation marker of colon cancer cells), and attenuated that of proliferating cell nuclear antigen at the mRNA level in a dose-dependent manner. "

Related Drugs and Biologics

1.	Enzymes
2.	Proliferating Cell Nuclear Antigen (PCNA)
3.	Messenger RNA (mRNA)
4.	Disaccharides
5.	Differentiation Antigens