Succinate Cytochrome c Oxidoreductase

An electron transport chain complex that catalyzes the transfer of electrons from SUCCINATE to CYTOCHROME C. It includes ELECTRON TRANSPORT COMPLEX II and ELECTRON TRANSPORT COMPLEX III.

Also Known As:

Networked: 31 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Emmerzaal, Tim: 1 article (07/2020)
2.	Henckens, Marloes: 1 article (07/2020)
3.	Kirdar, Faisal: 1 article (07/2020)
4.	Kozicz, Tamas: 1 article (07/2020)
5.	Morava, Eva: 1 article (07/2020)
6.	Preston, Graeme: 1 article (07/2020)
7.	Schrader, Laura: 1 article (07/2020)
8.	Hassinen, Ilmo E: 1 article (01/2016)
9.	Hautakangas, Milla-Riikka: 1 article (01/2016)
10.	Hinttala, Reetta: 1 article (01/2016)

Related Diseases

1.	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/23/1995 - "We measured the activities of five respiratory chain enzymes in brain macrophages/microglial cells from Lewis rats with experimental autoimmune encephalomyelitis (EAE) and found a significant reduction of the activity of nicotinamide adenine dinucleotide-dehydrogenase (NADH-DH), succinate cytochrome c reductase (SCCR) and succinate dehydrogenase (SDH) when compared with age-matched healthy control animals. "
2.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2023 - "Prediction of drug-induced mitochondrial dysfunction using succinate-cytochrome c reductase activity, QSAR and molecular docking." 01/01/2016 - "Activities of NADH-ubiquinone reductase, NADH-cytochrome c reductase, succinate-cytochrome c reductase; ubiquinol-cytochrome c reductase and cytochrome c oxidase activities have log-normal distributions even when confirmed mitochondrial diseases were ruled out. "
3.	Mitochondrial Myopathies (Mitochondrial Myopathy) 10/01/1994 - "Benign mitochondrial myopathy with decreased succinate cytochrome C reductase activity." 05/01/1988 - "Mitochondrial myopathy with lactic acidaemia, Fanconi-De Toni-Debré syndrome and a disturbed succinate: cytochrome c oxidoreductase activity."
4.	Fanconi Syndrome (Syndrome, Fanconi) 01/01/1991 - "Fatal hepatic failure with lactic acidaemia, Fanconi syndrome and defective activity of succinate:cytochrome c reductase." 11/01/1993 - "Chloracetaldehyde reduces the activity of succinate-cytochrome c oxidoreductase, suggesting that a defect in ATP generation might play a role in the pathogenesis of Fanconi syndrome induced by IF. "
5.	Iron Overload 03/11/1994 - "To assess mitochondrial damage by iron overload, succinate-cytochrome c reductase and NADH-cytochrome c reductase activities as well as the rate of succinate-dependent hydrogen peroxide generation were measured. "

Related Drugs and Biologics

1.	Enzymes
2.	NADH Dehydrogenase
3.	Succinate Dehydrogenase (Fumarate Reductase)
4.	NAD (NADH)
5.	Electron Transport Complex IV (Cytochrome c Oxidase)
6.	L-Lactate Dehydrogenase (Lactate Dehydrogenase)
7.	Phospholipids (Phosphatides)
8.	Cholesterol
9.	Adenosine Triphosphate (ATP)
10.	Cytochromes c (Cytochrome c)

Related Therapies and Procedures

1.	Intravenous Administration