Street Drugs (Illicit Drugs)

Drugs obtained and often manufactured illegally for the subjective effects they are said to produce. They are often distributed in urban areas, but are also available in suburban and rural areas, and tend to be grossly impure and may cause unexpected toxicity.

Also Known As:

Networked: 1452 relevant articles (18 outcomes, 139 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Bodnar, Richard J: 13 articles (12/2014 - 12/2002)
2.	Nestler, Eric J: 9 articles (08/2014 - 11/2002)
3.	Nair, Madhavan P N: 7 articles (01/2015 - 02/2004)
4.	Manchikanti, Laxmaiah: 7 articles (07/2012 - 04/2003)
5.	Wood, Evan: 6 articles (09/2015 - 01/2003)
6.	West, Cameron: 6 articles (09/2012 - 05/2010)
7.	Pampati, Vidyasagar: 6 articles (07/2012 - 04/2003)
8.	Damron, Kim S: 6 articles (07/2012 - 04/2003)
9.	Kerr, Thomas: 5 articles (09/2015 - 09/2005)
10.	Degenhardt, Louisa: 5 articles (09/2014 - 07/2007)

Related Diseases

1.	Substance-Related Disorders (Drug Abuse) 08/01/2010 - "There is very little research on remission from drug dependence; definitions used are often imprecise and inconsistent across studies and there remains considerable uncertainty about the longitudinal course of dependence upon these most commonly used illicit drugs." 04/01/2000 - "Because, to our knowledge, no other intervention has successfully altered substance abuse by athletes, we developed and assessed the efficacy of a team-centered, sex-specific education program designed to reduce adolescent athletes' intentions to use and use of AS and alcohol and other illicit drugs. " 03/01/2004 - "The purpose of this article is (a) to review studies that have examined the relationship of drug abuse and child neglect, (b) to review clinical treatments that appear to be effective in both perpetrators of child neglect and drug-abusing adolescents, and (c) to integrate empirically validated drug abuse and child neglect interventions for use in adolescent mothers who have been found to abuse drugs and neglect their children." 10/01/2013 - "Based on our analysis, we found evidence that the transitions from homelessness are closely associated with a reduction in the use of alcohol and illicit drugs, a decline in drug addiction severity, and an improvement in mental health. " 01/01/2015 - "Using interview data from 21 service providers of substance abuse and related service organizations located in and/or serving predominantly populations of color, this study explored perceptions of harm reduction programming for illicit drugs and race in the US. "
2.	Infection 10/01/2014 - "Specialist support services for MSM with HIV who use recreational drugs might be beneficial in the reduction of harm and prevention of ongoing transmission of HIV and other sexually transmitted infections. " 09/01/2009 - "These studies elucidate the molecular mechanisms underlying the effects of drugs of abuse on HIV-1 infections. " 01/01/2008 - "Research is encouraged to study interactions between infections, drugs of abuse, and underlying pathophysiologic and molecular/genetic mechanisms of these interactions." 07/01/1995 - "HCV infection occurs quickly after the initiation of injecting illicit drugs, with 78% of study participants anti-HCV positive after 2 years of injecting. " 12/15/2015 - "Some illicit drugs are associated with rare infections, which are difficult to diagnosis with standard microbiological techniques. "
3.	Alcoholism (Alcohol Abuse) 10/01/2004 - "The advances, with the discovery of specific receptors and the existence of naturally occurring cannabis-like substances in the mammalian system and brain, have helped in understanding the neurobiological basis for drugs of abuse, including alcoholism. " 11/01/1999 - "Both studies also found high rates of comorbid alcohol abuse, depression, and multiple drugs of abuse in the mothers. " 01/01/1985 - "The use of event-related potentials in the study of alcoholism: implications for the study of drugs of abuse." 05/01/2014 - "Cox proportional hazards regression was conducted predicting age at first use of alcohol, first alcohol intoxication, first use and regular use of cigarettes, and first use of cannabis and other illicit drugs from dummy variables coding for parental alcoholism and parental separation. " 11/01/2013 - "Older age, past school failure, illicit drugs use, alcohol abuse, high levels of perceived stress, and the death of at least one parent were associated with high scores for all subscales. "
4.	Premature Birth (Birth, Premature) 02/01/2008 - "Violence was associated with preterm birth even after controlling for age, marital status, education, income, parity, planned pregnancy, antenatal care, smoking, alcohol, and illicit drugs use (odds ratio = 3.14, 95% confidence interval, 2.00-4.93). " 01/01/2007 - "Exposure to illicit drugs in utero is associated with low birth weight and premature birth. " 05/23/2011 - "Exposure to drugs of abuse during pregnancy may increase MTCT of HIV through a variety of mechanisms including possible damage to the placenta, induction of preterm birth, and increasing maternal plasma viral load through a variety of putative mechanisms such as: a) promoting HIV mutation and replication through non-adherence to HAART; b) impairing the efficacy of HAART through drug-drug interaction; and c) promoting HIV replication in monocyte/macrophages. " 12/01/2010 - "Exposure to drugs of abuse during pregnancy may increase MTCT of HIV through a variety of mechanisms that are addressed in detail including possible damage to the placenta, induction of preterm birth, and increasing maternal plasma viral load though a variety of putative mechanisms such as: (a) promoting HIV replication in monocyte/macrophages; (b) increasing the expression of CCR5 receptors; (c) decreasing the expression of CCR5 receptor ligands; (d) increasing the expression of CXCR4 receptors; (e) increasing the expression of DC-SIGN; (f) impairing the efficacy of HAART through drug-drug interaction; and (g) promoting HIV mutation and replication through non-adherence to HAART."
5.	Pain (Aches) 09/01/2010 - "Of the 10 participants who completed the 6 month follow-up, 8 reported improved pain control and physical functioning and 5 used alcohol and/or illicit drugs. " 11/01/2015 - "Study participants described using cannabis as a safer alternative for alcohol, illicit drugs and pharmaceuticals based on their perceptions of less adverse side effects, low-risk for addiction and greater effectiveness at relieving symptoms, such as chronic pain. " 03/01/2015 - "The results of the present study suggest that the denial of pain medication is associated with the use of illicit drugs while hospitalized. " 09/01/2012 - "A number of studies indicate that 10.8%-34% of patients with chronic pain use illicit drugs. " 09/01/2011 - "Findings from this study suggest that chronic pain is a significant problem in this high risk, socioeconomically disadvantaged group of patients with HIV disease and high rates of previous or concurrent use of illicit drugs. "

Related Drugs and Biologics

1.	Cocaine (Cocaine HCl)
2.	Nicotine
3.	Methamphetamine (Desoxyn)
4.	Heroin (Diamorphine)
5.	kappa Opioid Receptors (kappa Opioid Receptor)
6.	3- rhamnopyranosyl(1- 4)- glucopyranosyl- 12- diacetoxy- 20- hydroxywitha- 5,24- dienolide
7.	Ligands
8.	Poisons
9.	CXCR4 Receptors (CXCR4 Receptor)
10.	CCR5 Receptors (CCR5 Receptor)

Related Therapies and Procedures

1.	Highly Active Antiretroviral Therapy (HAART)
2.	Analgesia
3.	Drug Therapy (Chemotherapy)
4.	Self Administration (Administration, Self)
5.	Tracheotomy