Gastric Dilatation (Stomach Dilatation)

Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.

Also Known As:

Networked: 255 relevant articles (9 outcomes, 17 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Intestinal Volvulus (Volvulus)
2.	Morbid Obesity
3.	Weight Gain
4.	Reperfusion Injury
5.	Necrosis

Experts

1.	Giunti, Massimo: 4 articles (11/2021 - 01/2018)
2.	Bruchim, Yaron: 4 articles (10/2018 - 05/2007)
3.	Rauserova-Lexmaulova, Leona: 3 articles (01/2022 - 07/2015)
4.	Rehakova, Kristina: 3 articles (01/2022 - 07/2015)
5.	Spinella, Giuseppe: 3 articles (01/2020 - 12/2014)
6.	Valentini, Simona: 3 articles (01/2020 - 12/2014)
7.	Vanova-Uhrikova, Ivana: 2 articles (01/2022 - 06/2020)
8.	Calipa, Stefano: 2 articles (11/2021 - 01/2018)
9.	Davrieux, Carlos Federico: 2 articles (10/2021 - 02/2021)
10.	Palermo, Mariano: 2 articles (10/2021 - 02/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Gastric Dilatation:

1.	Lidocaine (Xylocaine)FDA LinkGeneric 08/01/2012 - "To assess the efficacy of IV lidocaine in decreasing complication rate and improving the outcome in dogs with gastric dilatation volvulus (GDV). " 01/01/2018 - "Serial evaluation of serum total reduction power potential by cyclic voltammetry in 30 dogs with gastric dilatation and volvulus- a randomised, controlled (lidocaine vs placebo), clinical trial." 05/01/2007 - "Evaluation of lidocaine treatment and risk factors for death associated with gastric dilatation and volvulus in dogs: 112 cases (1997-2005)." 05/01/2007 - "To determine clinical features, outcome, risk factors for death, and efficacy of IV administration of lidocaine as a prophylactic treatment for ischemic reperfusion injury in gastric dilatation and volvulus (GDV) in dogs. " 08/01/2012 - "Evaluation of lidocaine treatment on frequency of cardiac arrhythmias, acute kidney injury, and hospitalization time in dogs with gastric dilatation volvulus."
2.	SiliconesIBA 02/01/2017 - "Modified tube gastropexy using a mushroom-tipped silicone catheter is an effective and safe surgical method for the management of gastric dilatation-volvulus. " 02/01/2017 - "Modified tube gastropexy using a mushroom-tipped silicone catheter for management of gastric dilatation-volvulus in dogs."
3.	Diatrizoate Meglumine (Gastrograffin)FDA LinkGeneric 04/01/2020 - "The patient's symptoms improved 4 days later, and contrast-enhanced gastric X-ray using amidotrizoate meglumine revealed gastric peristalsis, passage of amidotrizoate meglumine into the duodenum, and no gastric dilatation. "
4.	Lactic Acid (Lactate)FDA LinkGeneric 01/01/2022 - "However, patients with arterial lactate level>2 mmol/l, or the absence of gastric dilation should be surgically explored due to a non-negligible risk of mortality." 01/01/2022 - "Multivariable analysis identified the following variables as independent predictors of mortality: arterial lactate level (OR: 1.39, 95% CI: 1.07-1.79) and the absence of gastric dilatation (OR: 0.07, 95% CI: 0.01-0.79). " 01/01/2022 - "Univariate analysis identified the following variables as predictive of mortality at the time of the diagnosis of GP: abdominal guarding, hemodynamic instability, arterial lactate level >2 mmol/l, and the absence of gastric dilatation. " 01/01/2020 - "Pre- and post-surgical evaluation of plasma lactate concentration in 45 dogs with gastric dilatation-volvulus: A preliminary study." 10/01/2018 - "Comparison of saphenous and cephalic blood lactate concentrations in dogs with gastric dilatation and volvulus: 45 cases."
5.	BariumIBA 07/01/2020 - "A barium swallow test showed gastric dilatation, delayed gastric emptying and an axial computed tomography revealed an aortomesenteric angle of 11.7°. " 07/01/2015 - "He underwent barium gastrointestinal transit and abdominal ultrasound, which revealed severe gastric dilatation, food retention and slow transit until a depressed duodenojejunal flexure, with malrotation of the midgut and jejunal loops being located in the right upper quadrant. " 04/01/2008 - "Original reports and images were reviewed to determine whether gastric peristalsis was decreased/absent and to investigate gastric dilatation, fluid or debris, and delayed emptying of barium. " 09/01/1984 - "During symptomatic phases upper gastrointestinal barium contrast radiographs demonstrated gastric dilatation with atony but without obstruction. " 04/01/2008 - "Barium studies revealed decreased gastric peristalsis in 46 (92%) of the 50 patients and absent peristalsis in four (8%); 46 patients (92%) had additional findings, including gastric dilatation in 30 (60%), delayed emptying of barium in 27 (54%), debris in 28 (56%; bezoars in three), and retained fluid in 13 (26%). "
6.	Radioisotopes (Radionuclides)IBA 10/01/1986 - "Gastric dilatation observed on radionuclide studies. " 12/01/2003 - "In all patients, before and after pneumatic dilatation, gastric emptying time was measured with radionuclide method after eating a solid meal. " 03/01/1989 - "Gastric emptying of a radionuclide-labeled test meal was studied in 10 dogs that had been treated surgically for gastric dilatation-volvulus and in 10 clinically normal (control) dogs. " 03/01/1989 - "Gastric emptying of a radionuclide-labeled test meal after surgical correction of gastric dilatation-volvulus in dogs."
7.	MyoglobinIBA 06/01/2009 - "To determine whether myoglobin (Mb) is a useful prognostic indicator for outcome and to investigate any relationship between Mb and mortality in dogs with gastric dilatation-volvulus (GDV). " 06/01/2009 - "Myoglobin as a prognostic indicator for outcome in dogs with gastric dilatation-volvulus." 03/01/2006 - "The purpose of this study was to evaluate the Cardiac Reader, a human point-of-care system for the determination of cTnT and myoglobin, and the Abbott Axsym System for the determination of cTnI and creatine kinase isoenzyme MB (CK-MB) in healthy dogs and in dogs at risk for acute myocardial damage because of gastric dilatation-volvulus (GDV) and blunt chest trauma (BCT). "
8.	Lipase (Acid Lipase)FDA Link 01/01/2018 - "Presurgical cPLI and lipase activity were frequently increased during gastric dilatation-volvulus and were suggestive of the presence of pancreatic damage; while more extensive studies are required, based on this pilot analysis, cPLI has the potential to be a useful predictive variable for outcome in GDV. " 01/01/2018 - "Prognostic value of canine pancreatic lipase immunoreactivity and lipase activity in dogs with gastric dilatation-volvulus." 01/01/2018 - "Canine pancreatic lipase immunoreactivity values above 400 μg/L were detected in 6/22 dogs with gastric dilatation-volvulus and 4/16 with intestinal obstruction. " 01/01/2018 - "T0 cPLI and serum lipase activity were not found to differ significantly between dogs with gastric dilatation-volvulus or intestinal obstruction. " 07/01/2012 - "To evaluate serum canine pepsinogen-A (cPG-A), C-reactive protein (CRP), and canine pancreatic lipase immunoreactivity (cPLI) concentrations in dogs with gastric dilatation-volvulus (GDV). "
9.	Contrast MediaIBA 04/01/2007 - "Diagnosis is based on transit studies using a hydroluble contrast agent which reveals major gastric dilation and a clear interruption of the transit at the level of the third duodenum as well as retrograde peristaltism. " 04/01/2022 - "In addition, 70 rabbits that had received the contrast agent diatrizoate because of gastric dilatation and suspected intestinal obstruction were retrospectively evaluated during a period of one year. " 04/01/2022 - "The use of the iodine-containing contrast agent diatrizoate was investigated in healthy rabbits and in rabbits with gastric dilatation and intestinal obstruction. "
10.	Therapeutic UsesIBA 11/01/2008 - "Therapeutic effects of sleeve gastrectomy plus gastric remnant banding on weight reduction and gastric dilatation: an animal study." 11/01/2008 - "Our objective was to observe the therapeutic effects of sleeve gastrectomy plus gastric remnant banding on weight reduction and gastric dilatation in an SD rat model. "

Therapies and Procedures

1.	Gastrectomy 11/01/2008 - "Sleeve gastrectomy plus gastric remnant banding is safe and effective because of the restriction of postoperative gastric dilation." 02/01/2006 - "The efficacy of laparoscopic sleeve gastrectomy (LSG) for morbidly obese patients with a BMI of <50 kg/m2 and the incidence of gastric dilatation following LSG have not yet been investigated. " 03/01/2008 - "The aim of this study was to prevent gastric dilation after sleeve gastrectomy. " 03/01/2008 - "However, short-term weight regain may occur owing to gastric dilation after initial laparoscopic sleeve gastrectomy. " 10/01/2021 - "Sleeve gastrectomy for idiopathic acute gastric dilatation with transmural necrosis."
2.	Gastropexy 12/01/2002 - "Prospective evaluation of laparoscopic-assisted gastropexy in dogs susceptible to gastric dilatation." 06/01/1992 - "Intermittent gastric dilatation after gastropexy in a dog." 02/01/1980 - "Recurrent canine gastric dilation corrected by gastropexy and pyloroplasty." 07/01/2016 - "Temporary percutaneous T-fastener gastropexy and continuous decompressive gastrostomy in dogs with experimentally induced gastric dilatation." 01/01/2016 - "This study shows that the recurrence of gastric dilatation volvulus after ventral midline gastropexy is low and adhesion of the stomach to the abdominal wall is persistent in almost all dogs that were re-examined. "
3.	Sutures (Suture) 04/01/1984 - "In a randomized prospective trial, 52 patients with suture lines constructed in the gastrointestinal tract received no postoperative nasogastric drainage unless acute gastric dilation or copious vomiting developed postoperatively, while 45 similar patients were allocated to receive routine postoperative nasogastric aspiration. " 04/01/2021 - "This study evaluated the feasibility and efficacy of a laparoscopic absorbable fixation device (Securestrap) in total laparoscopic gastropexy in dogs susceptible to gastric dilatation-volvulus (GDV) compared to laparoscopic gastropexy performed with a barbed suture. " 12/01/1994 - "Between January 1988 and December 1992, six patients presenting with chronic duodenal ulcer disease, long segment duodenal stricture, gross gastric dilatation and Forrest Ia hemorrhage from penetrating posterior duodenal wall ulcer were managed by oblique duodenal transsection, suture ligation of arroded pancreaticoduodenal vessel, classic Billroth II resection, Nissen duodenojejunostomy and a Tomoda valve disconnecting the Nissen anastomosis from the gastroenterostomy, -resulting in a functional "uncut" Roux anastomosis. "
4.	Decompression 04/01/1998 - "In our case, the patient's symptoms were improved by prokinetic agents and timely decompression in life-threatening acute gastric dilatation." 07/01/2022 - "Medical stabilization included gastric decompression and placement of an indwelling nasogastric tube to prevent further gastric dilatation in all dogs. " 11/01/2017 - "This report is related to the unusual case of an 11-year-old boy presenting with acute gastric dilatation after the intake of excessive food and carbonated beverages after a 12-hour fasting who died of complications of acute reperfusion syndrome after decompression of the stomach with gastrotomy. " 09/01/2017 - "WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: This case highlights the rare though potentially catastrophic complications of acute gastric dilatation, and benefits of early intervention with gastric decompression." 11/01/2016 - "Acute gastric dilatation is a rare cause of gas within the hepatic portal vein, but one that is important to recognise as prompt decompression via a nasogastric tube is usually successful in resolving the situation. "
5.	Catheters 02/01/1998 - "Problems arising from the operative technique are: early pouch dilatation, gastric slippage, gastric perforation, penetration of the band, port infection, penetration of the port, defect of the band catheter. " 11/01/2019 - "To evaluate the feasibility of ultrasound-guided, temporary, percutaneous T-fastener gastropexy (TG) and gastrostomy catheter (GC) placement for providing sustained gastric decompression in dogs with acute gastric dilatation-volvulus (GDV) and to compare findings with those of trocarization. " 11/01/2019 - "Evaluation of a novel technique involving ultrasound-guided, temporary, percutaneous gastropexy and gastrostomy catheter placement for providing sustained gastric decompression in dogs with gastric dilatation-volvulus." 02/01/2017 - "Modified tube gastropexy using a mushroom-tipped silicone catheter is an effective and safe surgical method for the management of gastric dilatation-volvulus. " 02/01/2017 - "Modified tube gastropexy using a mushroom-tipped silicone catheter for management of gastric dilatation-volvulus in dogs."