Spinocerebellar Degenerations (Marinesco Sjogren Syndrome)

A heterogenous group of degenerative syndromes marked by progressive cerebellar dysfunction either in isolation or combined with other neurologic manifestations. Sporadic and inherited subtypes occur. Inheritance patterns include autosomal dominant, autosomal recessive, and X-linked.
Also Known As:
Marinesco Sjogren Syndrome; Spinocerebellar Degeneration; Ataxia, Hereditary; Hereditary Ataxia; Syndrome, Marinesco-Sjogren; Early Onset Cerebellar Ataxia; Late Onset Cerebellar Ataxia; Spinocerebellar Diseases; Corticostriatal Spinal Degeneration; Hereditary Ataxias; Spinocerebellar Disease; Familial Spinocerebellar Degenerations; Hereditary Spinocerebellar Degenerations; Inherited Spinocerebellar Degenerations; Marie's Cerebellar Ataxia; Spino Cerebellar Degenerations; Spino-Cerebellar Degenerations; Cerebellar Ataxia, Marie; Cerebellar Ataxia, Marie's; Cerebellar Degeneration, Primary; Corticostriatal-Spinal Degenerations; Degeneration, Corticostriatal-Spinal; Degeneration, Familial Spinocerebellar; Degeneration, Hereditary Spinocerebellar; Degeneration, Inherited Spinocerebellar; Degeneration, Primary Cerebellar; Degeneration, Spino Cerebellar; Degeneration, Spino-Cerebellar; Degeneration, Spinocerebellar; Degenerations, Corticostriatal-Spinal; Degenerations, Familial Spinocerebellar; Degenerations, Hereditary Spinocerebellar; Degenerations, Inherited Spinocerebellar; Degenerations, Primary Cerebellar; Degenerations, Spino Cerebellar; Degenerations, Spino-Cerebellar; Degenerations, Spinocerebellar; Familial Spinocerebellar Degeneration; Hereditary Spinocerebellar Degeneration; Inherited Spinocerebellar Degeneration; Maries Cerebellar Ataxia; Primary Cerebellar Degeneration; Primary Cerebellar Degenerations; Spino Cerebellar Degeneration; Spino-Cerebellar Degeneration; Spinocerebellar Degeneration, Familial; Spinocerebellar Degeneration, Hereditary; Spinocerebellar Degeneration, Inherited; Spinocerebellar Degenerations, Familial; Spinocerebellar Degenerations, Hereditary; Spinocerebellar Degenerations, Inherited; Ataxias, Hereditary; Cerebellar Ataxia, Early Onset; Cerebellar Ataxia, Late Onset; Cerebellar Degenerations, Primary; Corticostriatal-Spinal Degeneration; Marie Cerebellar Ataxia; Marinesco-Sjogren Syndrome
Networked: 244 relevant articles (6 outcomes, 20 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Ataxia (Dyssynergia)
2. Friedreich Ataxia (Friedreich's Ataxia)
3. Parkinson Disease (Parkinson's Disease)
4. Tremor (Tremors)
5. Peripheral Nervous System Diseases (PNS Diseases)


1. Filla, Alessandro: 3 articles (01/2006 - 11/2002)
2. Alagoz, Meryem: 2 articles (03/2014 - 01/2013)
3. El-Khamisy, Sherif F: 2 articles (03/2014 - 01/2013)
4. Pandolfo, Massimo: 2 articles (10/2013 - 03/2011)
5. Manto, Mario: 2 articles (10/2013 - 09/2009)
6. Cheng, Wen-Ling: 2 articles (12/2012 - 12/2010)
7. Soong, Bing-Wen: 2 articles (12/2012 - 12/2010)
8. Lee, Yi-Chung: 2 articles (12/2012 - 12/2010)
9. Liu, Chin-San: 2 articles (12/2012 - 12/2010)
10. Masuda, Teruaki: 2 articles (04/2011 - 06/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Spinocerebellar Degenerations:
1. Thyrotropin-Releasing Hormone (Protirelin)FDA Link
2. DNA (Deoxyribonucleic Acid)IBA
3. Carbon MonoxideIBA
4. Amino AcidsFDA Link
5. Levodopa (L Dopa)FDA LinkGeneric
6. AntibodiesIBA
7. Vitamin EFDA LinkGeneric
8. polyglutamineIBA
9. Proteins (Proteins, Gene)IBA
10. Spastic ataxia Charlevoix-Saguenay typeIBA

Therapies and Procedures

1. Transplants (Transplant)
2. Heterologous Transplantation (Xenotransplantation)
3. Cell Transplantation
4. Anesthesia
5. Activities of Daily Living (ADL)