Spinal Stenosis (Stenosis, Spinal)

01/01/2015 - "There is a fair short-term and long-term benefit for treating spinal stenosis with local anesthetic and steroids. "
07/01/2012 - "For spinal stenosis, the evidence is fair for local anesthetic, with or without steroids. "
05/01/2012 - "For spinal stenosis, the available evidence is fair for local anesthetic and steroids. "
10/01/1997 - "Spine epidural steroids for patients with lumbar spinal stenosis."
01/01/2015 - "Comments on a systematic review and meta-analysis of steroids for epidural injections in spinal stenosis."

02/01/2015 - "The efficacy of intramuscular calcitonin injection in the management of lumbar spinal stenosis."
10/31/2009 - "The efficacy of physical therapy and physical therapy plus calcitonin in the treatment of lumbar spinal stenosis."
11/01/2004 - "Several small trials in the past have suggested that subcutaneous and intramuscular calcitonin is an effective nonsurgical option in treating the symptoms of spinal stenosis patients. "
12/01/1989 - "This study investigates the clinical efficacy and safety of intramuscular calcitonin therapy in 15 lumbar spinal stenosis patients with a neurogenic claudication syndrome. "
02/01/2015 - "To assess the effectiveness of intramuscular calcitonin injection in the treatment of lumbar spinal stenosis (LSS). "

07/01/2014 - "A lipo-prostaglandin E1 agonist is effective for the treatment of neurological symptoms of spinal stenosis when administered by an oral or intravenous route. "
01/15/2009 - "The efficacy of prostaglandin E1 derivative in patients with lumbar spinal stenosis."
04/01/1999 - "Results of this study suggest that Lipo prostaglandin E1 may enhance blood flow in the cauda equina and improve clinical symptoms in some patients with lumbar spinal stenosis."
07/01/2014 - "We suggest that epidurally administered lipo-PGE1 may be a useful therapeutic candidate for patients with spinal stenosis."
07/01/2014 - "Therapeutic effect of epidurally administered lipo-prostaglandin e1 agonist in a rat spinal stenosis model."

11/01/2014 - "The purpose of this study was to analyze the therapeutic efficacy of pregabalin for reducing the incidence of spinal surgery for leg symptoms in patients with lumbar spinal stenosis during the first year of treatment. "
01/01/2014 - "The purpose of this study was to evaluate the therapeutic efficacy of pregabalin in patients with leg symptoms due to lumbar spinal stenosis. "
11/01/2014 - "However, the therapeutic efficacy of pregabalin for reducing the incidence of spinal surgery to treat leg symptoms in patients with lumbar spinal stenosis remains unknown. "
11/01/2014 - "One-year follow-up for the therapeutic efficacy of pregabalin in patients with leg symptoms caused by lumbar spinal stenosis."
01/01/2014 - "Therapeutic efficacy of pregabalin in patients with leg symptoms due to lumbar spinal stenosis."

04/20/2007 - "To investigate the efficacy of treatment with gabapentin on the clinical symptoms and findings in patients with lumbar spinal stenosis (LSS). "
04/20/2007 - "The efficiency of gabapentin therapy in patients with lumbar spinal stenosis."
03/01/2014 - "The effects of gastroretentive gabapentin (Gralise®) on spinal stenosis patients with radicular pain."
01/01/2010 - "The efficacy of gabapentin monotherapy was investigated against both acute or chronic radicular pain caused by lumbar disk hernia (LDH) or lumbar spinal stenosis (LSS). "
01/01/2010 - "Efficacy of gabapentin for radiculopathy caused by lumbar spinal stenosis and lumbar disk hernia."

07/01/2003 - "These data suggest that the therapeutic effect of OP-1206 alpha-CD is primarily mediated by the improved local SCBF at the territory of spinal stenosis and not due to improvement of peripheral perfusion and/or antiplatelet activity."
06/01/2002 - "These data show that oral treatment with OP-1206 alpha-CD is effective in improving walking dysfunction induced by spinal canal stenosis, and this therapeutic effect is likely mediated by improved SCBF at the territory of spinal stenosis. "
10/01/2003 - "To determine whether the OP-1206 alpha-CD in combination with loxoprofen-Na could induce a greater therapeutical effect on walking dysfunction and spinal cord blood flow (SCBF) than OP-1206 alpha-CD treatment alone after chronic spinal stenosis in the rat. "
10/01/2003 - "An orally active prostaglandin E1 analogue, OP-1206 alpha-CD improves walking dysfunction in the rat spinal stenosis model. "
06/01/2002 - "OP-1206 alpha-CD was administered orally bid for 11 days from postoperative Day 3. In Control nontreated rats, a significant walking dysfunction was observed from Day 1 after the induction of spinal stenosis and persisted for 14 days when compared with the Sham-Operated group. "

11/01/2009 - "There have not been any randomized trials evaluating the effectiveness of percutaneous adhesiolysis and targeted delivery of local anesthetic, steroid and hypertonic sodium chloride solution in lumbar spinal stenosis. "
11/01/2009 - "With significant pain relief in 76% of patients, percutaneous adhesiolysis utilizing local anesthetic, steroids and hypertonic sodium chloride solution may be effective in patients with chronic function-limiting low back and lower extremity pain with spinal stenosis."
07/01/2013 - "Percutaneous adhesiolysis utilizing local anesthetic steroids and hypertonic sodium chloride solution may be an effective management strategy in patients with chronic posterior neck and upper extremity pain due to cervical central spinal stenosis, although there is no correlation between therapeutic response and the grade of CCS."
01/01/2013 - "Significant relief and functional status improvement as seen in 71% of the 70 patients with percutaneous adhesiolysis utilizing local anesthetic steroids and hypertonic sodium chloride solution may be an effective management strategy in patients with chronic function limiting low back and lower extremity pain with central spinal stenosis after failure of conservatie management and fluoroscopically directed epidural injections."
12/01/1995 - "The results of postoperative epidural administration of saline solution (a placebo), morphine, methylprednisolone, and a combination of morphine and methylprednisolone for the reduction of pain after an operation for spinal stenosis or a herniated intervertebral disc were compared in a prospective, randomized blinded study. "

08/01/2009 - "The objective of this study is to evaluate the efficacy of corticosteroids in patients with radicular pain due to lumbar disc herniation or lumbar spinal stenosis through a prospective randomised, double blind controlled trial, and whether there was an effect on subsequent interventions such as additional root blocks or surgery. "
04/15/2005 - "Various studies have examined the therapeutic value of periradicular infiltration using treatment agents consisting of local anesthetic and corticosteroids for radicular pain, secondary to lumbar disc herniation and spinal stenosis. "
11/01/2015 - "Patients aged older than or equal to 50 years with moderate-to-severe leg pain and lumbar central spinal stenosis randomized to epidural injections of corticosteroids with lidocaine (n=200) or lidocaine only (n=200) were included. "
01/01/2012 - "Lumbar spinal stenosis is a commonly treated with epidural injections of local anesthetics and corticosteroids, however, these therapies may relieve leg pain for weeks to months but do not influence functional status. "

06/01/2009 - "An open study of pamidronate in the treatment of refractory degenerative lumbar spinal stenosis."
09/11/1995 - "To our knowledge, this is the first report of the use of intravenous pamidronate disodium as the sole treatment of lower limb weakness attributable to pagetic spinal stenosis. "
09/11/1995 - "Pamidronate treatment of the neurologic sequelae of pagetic spinal stenosis."
04/01/1994 - "To reduce the unsuccessful results, patients with segmental instability or spinal stenosis after open surgery should not be treated by APD."
12/01/2009 - "The efficacy of pamidronate in patients with spondyloarthropathies; synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome; hypertrophic osteoarthropathy; osteoporotic vertebral fractures; chronic back pain due to disk disease or spinal stenosis; Charcot arthropathy; transient osteoporosis; and complex regional pain syndrome-I, has been demonstrated in more than 40 reports, the majority of which, however, were not controlled studies. "

06/01/2010 - "The Dynesys system is also effective in the treatment of DDD combined with spinal stenosis in elderly patients, as reported by other authors. "
10/01/2013 - "Twenty systematic reviews were included which covered the following diagnoses: disc herniation (n = 9), spondylolisthesis (n = 2), spinal stenosis (n = 3), DDD (n = 4) and combinations (n = 2). "
09/01/2013 - "Thirteen systematic reviews on surgical interventions for low back disorders were included for disc herniation (n = 6), spondylolisthesis (n = 2), spinal stenosis (n = 4), and DDD (n = 4). "
09/01/2013 - "The following conditions were included: disc herniation, spondylolisthesis, and DDD with or without spinal stenosis. "
04/01/2013 - "For the degenerative lumbar spine disorders (disc herniation, spinal stenosis, spondylolisthesis and DDD) significant improvements are seen in all aspects as exemplified by pronounced improvement regarding EQ-5D and ODI. "

12/01/2007 - "For degenerative lumbar spinal stenosis unilateral approaches allowed sufficient and safe decompression of the neural structures and adequate preservation of vertebral stability, resulted in a highly significant reduction of symptoms and disability, and improved health-related quality of life."
01/01/1997 - "We found that in patients suffering degenerative spinal stenosis for up to 8 years, decompression without fusion showed the best results. "
03/01/1996 - "The first decompression operation for spinal stenosis has the best opportunity for a good outcome. "
09/01/2015 - "The bilateral and unilateral interlaminar techniques for bilateral decompression both demonstrate good results for the treatment of degenerative lumbar spinal stenosis (DLSS). "
06/01/2014 - "We obtained moderate-quality evidence indicating that postoperative active rehabilitation after decompression surgery for lumbar spinal stenosis is more effective than usual care. "

07/01/2010 - "CONCLUSIONS Lumbar laminectomy appears to be the most cost-effective treatment strategy for patients with symptomatic lumbar spinal stenosis."
05/01/2013 - "There is significant clinical improvement after laminectomy and dynamic stabilization with Dynesys for lumbar spinal stenosis. "
01/01/2013 - "There is significant clinical improvement after laminectomy and dynamic stabilization for symptomatic lumbar spinal stenosis. "
07/01/2001 - "Our conclusion in lumbar spinal stenosis diagnosed by objective clinical and radiological findings is that decompressive laminectomy and extensive foraminotomy without instrumentation allow a good outcome."
10/01/1987 - "We conclude that TLS laminectomy is an effective treatment for spinal stenosis if performed early in the course of the neurologic syndrome. "

12/01/2011 - "Epidural steroid injections is an effective treatment for improving ambulation and functional limitations caused by lumbar spinal stenosis. "
11/01/2012 - "Epidural steroid injections (ESI) are therapeutically useful for the treatment of herniated intervertebral discs and spinal stenosis. "
08/01/2013 - "Re: Radcliff K, Kepler C, Hilibrand A, et al. Epidural steroid injections are associated with less improvement in patients with lumbar spinal stenosis: a subgroup analysis of the spine patient outcomes research trial. "
08/01/2013 - "Re: Radcliff K, Kepler C, Hilibrand A, et al. Epidural steroid injections are associated with less improvement in patients with lumbar spinal stenosis: a subgroup analysis of the spine patient outcomes research trial. "
02/15/2013 - "Epidural steroid injections are associated with less improvement in patients with lumbar spinal stenosis: a subgroup analysis of the Spine Patient Outcomes Research Trial."

02/01/2015 - "Recent randomized trials, systematic reviews and guidelines have reached varying conclusions about the efficacy of epidural injections in the management of central lumbar spinal stenosis. "
02/01/2015 - "The aim of this systematic review was to determine the efficacy of all three anatomical epidural injection approaches (caudal, interlaminar, and transforaminal) in the treatment of lumbar central spinal stenosis. "
02/01/2015 - "Efficacy of epidural injections in the treatment of lumbar central spinal stenosis: a systematic review."
01/01/2015 - "Epidural injections are one of the commonly performed nonsurgical interventions in managing central spinal stenosis; however, there has been paucity of literature in reference to efficacy of epidural injections in managing central spinal stenosis with lumbar interlaminar epidural injections. "
09/01/2004 - "Because conservative therapy was not helpful for spinal stenosis and neuroclaudication, a left L2 transforaminal epidural injection was attempted, but a posterolateral fusion mass made this procedure impossible. "

02/01/2011 - "Traditionally, the most effective treatment for degenerative lumbar spinal stenosis is through surgical decompression. "
03/01/1995 - "Long-term follow-up studies of surgical decompression for intervertebral disk herniation and spinal stenosis have resulted in good outcomes in appropriately selected patients."
01/01/2015 - "Is interspinous process device implantation more effective in the short term (eight weeks) than conventional surgical decompression for patients with intermittent neurogenic claudication due to lumbar spinal stenosis? "
01/01/2013 - "To assess whether interspinous process device implantation is more effective in the short term than conventional surgical decompression for patients with intermittent neurogenic claudication due to lumbar spinal stenosis. "
02/01/2011 - "Efficacy of interspinous device versus surgical decompression in the treatment of lumbar spinal stenosis: a modified network analysis."