Spinal Diseases (Disease, Spinal)

03/01/1993 - "These results indicate excellent safety and efficacy for use of gadoteridol in children with suspected intracranial or spinal disease."
12/01/1991 - "Clinical safety and efficacy of gadoteridol: a study in 411 patients with suspected intracranial and spinal disease."
12/01/1991 - "In this phase III study, 411 adult patients with suspected intracranial or spinal disease underwent magnetic resonance (MR) imaging before and after intravenous injection of 0.1 mmol/kg gadoteridol (gadolinium 1,4,7-tris [carboxymethyl]-10-[2'-hydroxypropyl]-1,4,7,10-tetraazacyclododecane+ ++). "
01/01/1991 - "As part of a phase III clinical trial, 25 patients with suspected intracranial or spinal disease underwent magnetic resonance (MR) imaging before and after intravenous injection of 0.1 mmol/kg Gd-HP-DO3A (1,4,7-tris[carboxymethyl]-10-[2' hydroxypropyl]-1,4,7,10- tetraazacyclododecane), a neutral (nonionic) gadolinium chelate. "

05/25/1993 - "Forty-one lesions of intracranial and spinal diseases underwent magnetic resonance (MR) imaging at both standard-dose (0.1 mmol/kg) and double-dose (0.2 mmol/kg) levels of gadolinium (Gd)-DTPA in order to reassess the optimal dose of Gd-DTPA. "
01/01/1993 - "Gadolinium contrast agents represent one of the most important advances in MR imaging of spinal disease. "
12/01/1991 - "In this phase III study, 411 adult patients with suspected intracranial or spinal disease underwent magnetic resonance (MR) imaging before and after intravenous injection of 0.1 mmol/kg gadoteridol (gadolinium 1,4,7-tris [carboxymethyl]-10-[2'-hydroxypropyl]-1,4,7,10-tetraazacyclododecane+ ++). "
01/01/1991 - "As part of a phase III clinical trial, 25 patients with suspected intracranial or spinal disease underwent magnetic resonance (MR) imaging before and after intravenous injection of 0.1 mmol/kg Gd-HP-DO3A (1,4,7-tris[carboxymethyl]-10-[2' hydroxypropyl]-1,4,7,10- tetraazacyclododecane), a neutral (nonionic) gadolinium chelate. "
09/01/1990 - "Recently, the application of intravenous gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) has been shown to improve the detection of intradural extramedullary spinal disease in adults. "

08/01/2012 - "Anterior interbody fusion of the cervical spine have become the gold standard for treating spinal diseases, hence the aim of this study was to compare long term follow up results in patients with cervical disk disease treated with anterior PEEK cage implantation and without it in anterior approach. "
05/01/2009 - "Forty patients with degenerative spinal disease were treated with a monosegmental spondylodesis (ventrally, 1 PEEK-cage; dorsally, a screw and rod system), and randomly placed in two groups. "

11/01/2014 - "Comparative efficacy of levobupivacaine and ropivacaine for epidural block in outpatients with degenerative spinal disease."
11/01/2014 - "This study was carried out to evaluate the comparative efficacy of levobupivacaine and ropivacaine for epidural block in outpatients with degenerative spinal disease and sciatica. "
11/01/2014 - "The results showed that 0.125% levobupivacaine and 0.2% ropivacaine for epidural block by a caudal approach provide similar lumbosacral pain relief, hemodynamic effects, and the degree and the recovery of motor blockade in outpatients with degenerative spinal disease and sciatica."

11/01/2014 - "Comparative efficacy of levobupivacaine and ropivacaine for epidural block in outpatients with degenerative spinal disease."
11/01/2014 - "This study was carried out to evaluate the comparative efficacy of levobupivacaine and ropivacaine for epidural block in outpatients with degenerative spinal disease and sciatica. "
11/01/2014 - "The results showed that 0.125% levobupivacaine and 0.2% ropivacaine for epidural block by a caudal approach provide similar lumbosacral pain relief, hemodynamic effects, and the degree and the recovery of motor blockade in outpatients with degenerative spinal disease and sciatica."

05/25/1993 - "[Contrast-enhanced MR imaging using double doses of gadolinium-DTPA in evaluating brain and spinal diseases]."
09/01/1988 - "A total of 209 intracranial and spinal diseases were evaluated before and after administration of the paramagnetic contrast agent Gd-DTPA. "
09/01/1988 - "Gadolinium-DTPA in spinal disease."
04/01/1988 - "Gadolinium-DTPA in the evaluation of intradural extramedullary spinal disease."
05/25/1993 - "Forty-one lesions of intracranial and spinal diseases underwent magnetic resonance (MR) imaging at both standard-dose (0.1 mmol/kg) and double-dose (0.2 mmol/kg) levels of gadolinium (Gd)-DTPA in order to reassess the optimal dose of Gd-DTPA. "

12/01/2010 - "This systematic review assesses the efficacy of epidural steroids on adults undergoing lumbar spine surgery for degenerative spinal disease. "
12/01/2010 - "Perioperative epidural steroids for lumbar spine surgery in degenerative spinal disease. "
04/01/2007 - "The use of lumbar epidural/transforaminal steroids for managing spinal disease."
02/01/2002 - "The analgesic mechanism of epidural steroids in reducing pain associated with degenerative spinal disease (DSD) is poorly understood. "
12/01/2010 - "There is evidence that epidural steroids decrease pain in the short term and shorten length of stay in adults undergoing lumbar spinal surgery for degenerative spinal disease. "

07/01/2005 - "Tumor necrosis factor blockers are effective and safe in active spinal disease, but simple measures such as exercise and nonsteroidal anti-inflammatory drug therapy are still considered the basis of standard therapy. "
06/01/2005 - "The recent introduction of tumor necrosis factor (TNF) blockers in the treatment of spondyloarthritis has offered the most hope in not only relieving symptoms and signs of both peripheral arthritis and enthesitis but also spinal disease, which often has been refractory to other agents. "

01/01/2014 - "Additionally, given the efficacy of TCZ in the treatment of RA, this review discusses how TCZ may be beneficial in the treatment of other autoimmune diseases, spinal disease, cardiovascular disease, organ transplantation, and malignancies where elevated levels of IL-6 may play a role in the pathogenesis of these diseases."

08/01/1991 - "Results have been variable, but data suggest that sulfasalazine is less effective for spinal disease than for peripheral joint involvement. "

08/01/1994 - "This approach provides a greater access to the anterior thoracic canal, and can achieve effective anterior decompression, and a good outcome for thoracic spinal disease if recognized early."
01/01/2008 - "The use of tubular retractors for microsurgical decompression of degenerative spinal disease is a safe and effective treatment modality. "
10/01/2013 - "This study showed that the TLIF procedure without pedicle screw support would be sufficient in the management of preoperatively stable patients with lumbar degenerative spinal disease requiring fusion after single-level decompression. "
06/01/2015 - "Complications were recorded prospectively in 1449 (1073 lumbar, 376 cervical) outpatients undergoing microsurgical decompression for degenerative spinal disease at the private Oslofjord Clinic from 2008 to 2013. "
12/01/2014 - "Adjacent segment pathology following anterior decompression and fusion using cage and plate for the treatment of degenerative cervical spinal diseases."

08/01/2014 - "Anterior cervical discectomy and fusion (ACDF) is a safe and effective procedure for degenerative cervical spinal disease unresponsive to conservative management and its outstanding results have been reported. "
12/01/2014 - "The study population consisted of 231 patients who underwent anterior cervical discectomy and fusion (ACDF) with cage and plate for degenerative cervical spinal disease. "
09/01/2013 - "From March 2010 to December 2010, 134 patients with degenerative cervical spinal disease were treated with anterior cervical discectomy and interbody fusion. "
03/01/1979 - "The second group comprises 22 patients in whom the diagnosis of pyogenic spinal disease was made only after failure of discectomy. "
12/01/2010 - "Search terms included "laminectomy," "discectomy," and "steroid." Randomized and quasi-randomized controlled trials of adults undergoing lumbar spinal surgery for degenerative spinal disease were included. "

03/01/2011 - "The authors' objective in the present study was to evaluate their approach and the results of balloon kyphoplasty in the upper thoracic spine in patients with metastatic spinal disease. "
09/01/2014 - "Balloon kyphoplasty (BKP) has been proven to be safe and effective in the management of pathological vertebral compression fracture (VCF) due to metastatic spinal disease. "
05/01/2015 - "The purpose of this technical report is to describe the utilization of a cortical screw trajectory along with kyphoplasty for a patient with an osteoporotic compression fracture as well as degenerative spinal disease. "
09/01/2013 - "With increasing popularity of percutaneous spinal access for minimally invasive spinal neurosurgery, the treatment paradigm has shifted from open approaches to vertebroplasty or kyphoplasty for degenerative spinal disease and vertebral compression fractures. "

04/01/2015 - "Ultrasound versus fluoroscopic-guided epidural steroid injections in patients with degenerative spinal diseases: a randomised study."
07/01/2013 - "Lumbar injections improved pain/disability related to discogenic lumbar spinal diseases. "
02/01/2015 - "Between June 2010 and February 2013, 43 patients with degenerative spinal disease and osteoporosis (T-score <-2.5) underwent lumbar fusion using cement-injectable cannulated pedicle screws. "

01/01/2005 - "Radiotherapy has been the primary therapy for managing metastatic spinal disease; however, surgery that decompresses the spinal cord circumferentially, followed by reconstruction and immediate stabilization, has also proven effective. "
07/01/2015 - "Treatment recommendations must take into consideration the risk-benefit profiles of surgical intervention and radiotherapy for the particular individual's circumstance, including neurologic status, performance status, extent of epidural disease, stability of the spine, extra-spinal disease status, and life expectancy. "
12/01/2014 - "Spinal instability as defined by the spinal instability neoplastic score is associated with radiotherapy failure in metastatic spinal disease."
11/01/2008 - "Radiotherapy for spinal disease may provide important symptom relief but the prognosis of these patients remains dramatically poor. "
12/01/2007 - "The last decade has witnessed a resurgence of interest in the surgical treatment of metastatic spinal disease to compliment radiotherapy. "