Sorbic Acid (Potassium Sorbate)

12/01/1978 - "A patient with contact urticaria with skin and respiratory symptoms was found to be sensitive to both sorbic acid and synthetic oil of cassia. "
12/01/1978 - "Contact urticaria from synthetic cassia oil and sorbic acid limited to the face."
11/01/1994 - "Sorbic acid is a preservative that can induce cutaneous vasodilation characterized by erythema, urticaria, and stinging when applied topically to humans. "
01/01/1982 - "Perioral contact urticaria from sorbic acid and benzoic acid in a salad dressing."
03/01/1988 - "In the objective, immediate non-immunologic contact urticaria tests with sorbic acid and benzoic acid, the stingers developed significantly more erythema to 0.5% sorbic acid (p less than 0.05) and to 1% benzoic acid (p less than 0.02). "

02/01/2008 - "To our knowledge, this is the first recorded case of contact dermatitis caused by sorbic acid in tobacco."
02/01/2008 - "[Tobacco contact dermatitis caused by sensitivity to sorbic acid]."
09/01/2005 - "Occupational contact dermatitis from potassium sorbate in milk transformation plant."
10/01/2000 - "Sorbic acid: an unusual cause of systemic contact dermatitis in an infant."
01/01/1996 - "Systemic contact dermatitis from sorbic acid."

07/01/1988 - "In the micronucleus assay, the highest dose of sorbic acid (150 mg/kg body weight) produced a significant increase in micronuclei formations compared to the distilled water control. "
09/01/1984 - "These levels of dietary sorbic acid had no significant effect on live body weight, feed conversion, mortality, or the incidence of leg abnormalities of these chicken broilers reared to roaster weight."
01/01/1992 - "Oral administration of sorbic acid (up to 5000 mg/kg body weight) did not induce sister chromatid exchanges or the formation of micronuclei in bone marrow cells of mice. "
06/01/2010 - "The median intakes of both benzoic acid and sorbic acid are well below the acceptable daily intakes of 0-5 and 0-25 mg kg(-1) body weight (bw) day(-1) for benzoic and sorbic acid, respectively. "
12/01/2001 - "Daily intake levels of these preservatives per person estimated from the concentration and daily consumption of foods were 6.23 mg, 0.0303 mg, 1.02 mg, 8.10 mg, and 25.0 mg, respectively, and assuming a body weight of 50 kg, the amounts of benzoic acid, p-hydroxybenzoic acid, and sorbic acid consumed were 2.5%, 0.2%, and 2.0% of their acceptable daily intakes, respectively. "

01/01/1998 - "Sorbic acid: a cause of immediate nonallergic facial erythema. "
04/01/1995 - "Recently we showed that cutaneous erythema similar to that associated with application of venzoic acid is induced by the topical administration of another preservative, sorbic acid, and is mediated by the increased biosynthesis of prostaglandin (PG)D2 in the skin. "
11/01/1994 - "Sorbic acid is a preservative that can induce cutaneous vasodilation characterized by erythema, urticaria, and stinging when applied topically to humans. "
02/01/1986 - "Sorbic acid-induced erythema, edema, and flare were not associated with mast cell degranulation. "
02/01/1986 - "Sorbic acid concentrations as low as 0.1% produced transient erythema with edema and flare after open or closed application to human skin. "

09/01/1981 - "Contact allergy to sorbic acid and Unguentum Merck."
12/01/2007 - "Loss of V-ATPase activity due to bafilomycin treatment or deletion of either VMA1 or VMA2 resulted in sorbic acid hypersensitivity and impaired vacuolar acidification, phenotypes also observed in both a kinase-inactive dbf2 mutant and cells completely lacking DBF2 (dbf2Delta). "
04/01/1976 - "Perfume allergy was detected in 3.6% of the cases, sensitivity to thiomersal in 2%, to sorbic acid in 0.8%, to parabens in only 0.3%, and to wool alcohols in 1.2%. "