Somatostatin (Somatotropin Release-Inhibiting Factor)

A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.
Also Known As:
Somatotropin Release-Inhibiting Factor; Somatotropin Release Inhibiting Hormone; SRIH-14; Somatofalk; Somatostatin, Cyclic; Stilamin; Somatostatin 14; Somatotropin Release Inhibiting Factor; Cyclic Somatostatin; Somatostatin-14; Somatotropin Release-Inhibiting Hormone
Networked: 7049 relevant articles (563 outcomes, 902 trials/studies)

Relationship Network

Bio-Agent Context: Research Results