Soft Tissue Neoplasms

Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.

Also Known As:

Networked: 70 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Sarcoma (Soft Tissue Sarcoma)
3.	Benign Fibrous Histiocytoma (Dermatofibroma)
4.	Neurilemmoma (Schwannoma)
5.	Neoplasm Metastasis (Metastasis)

Experts

1.	Thway, Khin: 1 article (01/2016)
2.	Jones, Robin L: 1 article (01/2016)
3.	Fisher, Cyril: 1 article (01/2016)
4.	Noujaim, Jonathan: 1 article (01/2016)
5.	Yoon, Nara: 1 article (01/2015)
6.	Moon, Ahrim: 1 article (01/2015)
7.	Kim, Hyun-Soo: 1 article (01/2015)
8.	Montgomery, Elizabeth A: 1 article (02/2014)
9.	Bishop, Justin A: 1 article (02/2014)
10.	Westra, William H: 1 article (02/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Soft Tissue Neoplasms:

1.	DNA (Deoxyribonucleic Acid)IBA 12/01/1991 - "Fine needle aspiration specimens from 29 patients with bone and soft tissue neoplasms were analyzed by flow cytometry for DNA index and cell cycle analysis to determine whether such studies were helpful in cytologic diagnosis. " 11/01/1993 - "Development and optimization of tissue preparative methodology for DNA content analysis of soft tissue neoplasms." 06/15/1997 - "Flow cytometric DNA content analysis of 185 soft tissue neoplasms indicates that S-phase fraction is a prognostic factor for sarcomas. " 11/01/1993 - "Development and optimization of tissue specific preparative techniques for DNA flow cytometry was undertaken prior to routine DNA content analysis of soft tissue neoplasms; 154 soft tissue tumors were studied. "
2.	GalliumIBA 01/01/1992 - "The efficacy of gallium scintigraphy in detecting malignant soft tissue neoplasms."
3.	Dermatofibrosarcoma protuberansIBA 07/01/2009 - "The objective of our study was to present the imaging features, including an MRI example, of dermatofibrosarcoma protuberans of the breast, an uncommon soft-tissue neoplasm of the breast, and review the literature. " 01/01/2014 - "Giant dermatofibrosarcoma protuberans (DFSP) of the scalp is a rare case, which is an intermediate grade soft tissue neoplasm originating from the dermal layer of the skin, which usually occurs in adults. " 03/30/2013 - "Dermatofibrosarcoma protuberans is an uncommon soft tissue neoplasm. " 01/01/2012 - "Dermatofibrosarcoma protuberans (DFSP) is an intermediate grade soft tissue neoplasm originating from the dermal layer of the skin. " 01/01/2012 - "Dermatofibrosarcoma protuberans (DFSP) is a soft tissue neoplasm of intermediate to low-grade malignancy. "
4.	Gadolinium DTPA (Magnevist)FDA Link 10/01/1994 - "[Gadolinium-DTPA combined with a fat suppression technique in studies with magnetic resonance at 0.5 T in soft-tissue neoplasms]." 10/01/1994 - "We combined a modified three-point Dixon technique for fat suppression with gadolinium-DTPA administration in the investigation of soft tissue neoplasms at 0.5 T. " 01/01/1994 - "The technique was combined with intravenous administration of gadolinium-DTPA in five patients with lumbosacral spine conditions, four patients with soft tissue neoplasms and three with skeletal neoplasms; all patients were examined at 0.5 T. "
5.	inhibin-alpha subunitIBA 12/01/2003 - "However, no study to date has evaluated alpha-inhibin immunoreactivity in soft-tissue neoplasms, which frequently enter the differential diagnosis of retroperitoneal masses. " 12/01/2003 - "However, the rarity of alpha-inhibin expression by soft-tissue neoplasms provides further support for its overall specificity as a marker of adrenal cortical differentiation in the biopsy evaluation of a retroperitoneal mass." 12/01/2003 - "We investigate the incidence of alpha-inhibin staining in a variety of soft-tissue neoplasms by using formalin-fixed, paraffin-embedded tissue sections from 282 previously classified soft-tissue neoplasms with anti-alpha-inhibin (Serotec, 1:75). "
6.	copper pyruvaldehyde bis(N(4)-methylthiosemicarbazone) complexIBA 01/01/1994 - "To evaluate whether [62Cu]Cu-PTSM could also serve as a blood flow tracer in PET studies of tumor tissue, the tumor uptake of [62Cu]Cu-PTSM was examined in dogs with spontaneously-occurring soft-tissue neoplasms. "
7.	tebufenozide (Mimic)IBA 08/01/2011 - "Cutaneous mycobacterial spindle cell pseudotumor: a potential mimic of soft tissue neoplasms." 09/01/1996 - "This case demonstrates that a tophus may mimic a soft-tissue neoplasm. " 01/01/1983 - "They may radiologically mimic other periosteal lesions or soft tissue neoplasms which erode bone." 01/01/2014 - "Liposarcoma often has pleomorphic histology and additionally may feature heterologous components that mimic other soft tissue neoplasms. " 03/01/2008 - "Melanoma has a propensity to mimic the morphologic appearances of a wide variety of epithelial and soft tissue neoplasms. "
8.	GadoliniumIBA 10/01/1994 - "The combination of gadolinium with the modified Dixon technique improves the demonstration of soft tissue neoplasms at 0.5 T and allows lesion size to be measured more accurately." 01/01/1994 - "In the patients with soft tissue neoplasms the combination of fat suppression and Gadolinium was helpful to assess lesion size. " 02/01/1998 - "The role of magnetic resonance imaging in the preoperative evaluation of the patient with a suspected primary osseous or soft tissue neoplasm is outlined, instances where magnetic resonance imaging potentially may make a specific diagnosis are outlined, the importance of gadolinium enhancement as an adjunct to native magnetic resonance imaging is stressed, and an algorithm for followup of patients after chemotherapy or definitive surgical treatment is presented. "
9.	AntibodiesIBA 10/01/2010 - "The authors have performed immunohistochemistry with antibodies against Sox9 in 106 chondroid and nonchondroid bone and soft tissue neoplasms. " 08/01/1995 - "By immunohistochemistry it marks with p30/32MIC2-directed antibodies but fails to react with antibodies associated with other soft tissue neoplasms. " 08/01/2000 - "Herein we will review the current status of immunohistochemical tumor markers in the diagnosis of soft tissue neoplasms and address some of the more recently described antibodies and their relative value and limitations for the diagnosis of these tumors."
10.	VimentinIBA 10/01/1996 - "Epithelioid sarcoma is a peculiar soft-tissue neoplasm of uncertain origin, which is characterized by an epithelioid morphology of tumor cells coexpressing epithelial (keratin) and nonepithelial (vimentin) antigens. " 07/01/1996 - "The distribution of vimentin, desmin, cytokeratins, lysozyme, factor VIII-related antigen, S-100 protein, and glial fibrillary acidic protein was studied both in CHP and in some canine soft-tissue neoplasms (seven fibrosarcomas, seven benign schwannomas, seven benign fibrous histiocytomas, and six leiomyosarcomas) used as controls for differential diagnosis. "

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 03/01/2012 - "[III. The role of chemotherapy for soft tissue neoplasm]." 01/01/2011 - "Systemic chemotherapy induced the remarkable improvement of the lesions, the infiltrative lung shadow and the soft tissue neoplasm. " 01/01/1969 - "[Locoregional chemotherapy in the treatment of soft tissue neoplasms]." 01/01/2003 - "Chemotherapy regimens are available for soft tissue neoplasms and osteosarcoma and are primarily designed to improve local control. " 02/01/1998 - "The role of magnetic resonance imaging in the preoperative evaluation of the patient with a suspected primary osseous or soft tissue neoplasm is outlined, instances where magnetic resonance imaging potentially may make a specific diagnosis are outlined, the importance of gadolinium enhancement as an adjunct to native magnetic resonance imaging is stressed, and an algorithm for followup of patients after chemotherapy or definitive surgical treatment is presented. "
2.	Transplants (Transplant) 01/01/1998 - "Skin carcinomas: planoepitheliale, spinocellulare, soft tissue neoplasms/mesenchymal sarcoma, larynx Ca planoepitheliale, lung: adenocarcinoma and Ca microcellulare, kidney Ca clarocellulare and post transplant non-Hodgkin lymphoma were diagnosed. "
3.	Hemipelvectomy 01/01/2012 - "En bloc resection of extra-peritoneal soft tissue neoplasms incorporating a type III internal hemipelvectomy: a novel approach."
4.	Electrodes (Electrode) 12/01/2003 - "Specifically, after the injection of the drug, sequences of 8 biphasic electric pulses lasting 50 + 50 micros each, with 1 ms interpulse intervals, were delivered in bursts of 1300 V/cm for cutaneous and soft tissue lesions, and of 800 V/cm for oral mucosal and exposed soft tissue neoplasms, using caliper electrodes. "