Snake Venoms (Snake Venom)

Solutions or mixtures of toxic and nontoxic substances elaborated by snake (Ophidia) salivary glands (Duvernoy's gland) for the purpose of killing prey or disabling predators and delivered by grooved or hollow fangs. They usually contain enzymes, toxins, and other factors.

Also Known As:

Networked: 1139 relevant articles (40 outcomes, 127 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Gutiérrez, José María: 27 articles (07/2021 - 11/2003)
2.	Soares, Andreimar M: 21 articles (04/2018 - 06/2002)
3.	Rucavado, Alexandra: 16 articles (07/2021 - 11/2003)
4.	Sampaio, Suely V: 16 articles (08/2019 - 12/2004)
5.	Casewell, Nicholas R: 15 articles (06/2022 - 01/2014)
6.	Escalante, Teresa: 15 articles (07/2021 - 11/2003)
7.	Harrison, Robert A: 14 articles (06/2022 - 06/2006)
8.	Isbister, Geoffrey K: 14 articles (01/2022 - 01/2007)
9.	Fox, Jay W: 14 articles (04/2016 - 03/2003)
10.	Lomonte, Bruno: 12 articles (01/2021 - 12/2002)

Related Diseases

1.	Snake Bites (Snake Bite) 06/01/2013 - "To demonstrate that use of lower doses of anti-snake venom is as effective as high doses and is associated with less complications and lower mortality especially in the wake of rising cost of medical treatment, the people most affected by snakebites being the poor farmers. " 12/01/2018 - "The results strongly show that Ikshusterol3-O-glucoside has a potent snake-venom neutralizing capacity and it might be a potential molecule for the therapeutic treatment for snakebites." 10/01/2018 - "The safety, efficacy, and homogeneity of anti-snake venoms are crucial for snakebite treatments to be effective with minimal adverse effects. " 10/01/2019 - "This study was done to evaluate the efficacy of use of anti-snake venom and ASV with fresh frozen plasma (FFP) in haemotoxic snake bites in a tertiary care hospital. " 01/01/2023 - "Our preliminary results may inform future studies on the effect of snake venoms upon plasmas from different age demographics and hope to reduce the burden of snakebite upon society."
2.	Bites and Stings (Sting) 01/01/2004 - "High-dose anti-snake venom versus low-dose anti-snake venom in the treatment of poisonous snake bites--a critical study." 10/01/1997 - "Many studies have examined the morphological and biochemical changes in the secretory epithelium of snake venom glands after a bite or milking. " 05/20/1982 - "Questionnaires returned from participants in the trial indicated that the test configuration was highly acceptable and an excellent correlation was obtained between clinical diagnosis and the detection and identification of snake venom in specimens of blood, urine or bite-site swab washings." 09/30/2023 - "Our findings provide new insights for the treatment of cobra bites and the development of snake venom-based medicines." 11/01/2020 - "Only 13% knew about 'big four', 18% knew 'dry bite', and 21% of subjects knew about anti-snake venom (ASV) used in India. "
3.	Neoplasms (Cancer) 04/01/2018 - "Snake venom toxins have shown promising results with high cytotoxicity against tumor cells, but their mechanisms of action remain unclear. " 06/27/2021 - "In this study, we investigated the pharmacological potential of crude Pseudocerastes and Eristicophis snake venoms in haematological disorders and cancer treatment. " 01/01/2021 - "India has a rich diversity of venomous snake fauna and, over the past two decades, several studies have demonstrated the anticancer potential of Indian snake venoms and their isolated components in cancer cell lines and animal tumor models. " 02/01/2020 - "Previous studies demonstrated that some snake venoms showed in vitro anti-cancer effects. " 01/01/2019 - "Several studies have pointed out that certain snake venoms contain compounds presenting cytotoxic activities that selectively interfere with cancer cell metabolism. "
4.	Thrombosis (Thrombus) 03/01/2022 - "Snake Venoms in Diagnostic Hemostasis and Thrombosis." 01/01/2013 - "Snake venom toxins have evolved to affect many prey physiological systems including hemostasis and thrombosis. " 04/01/2009 - "[Structures and functions of snake venom toxins affecting thrombosis and hemostasis]." 01/01/1990 - "Several snake venom constituents interfere in platelet aggregation, an important cellular process in thrombosis and hemostasis. " 12/01/2021 - "State-of-the-art review - A review on snake venom-derived antithrombotics: Potential therapeutics for COVID-19-associated thrombosis?"
5.	Necrosis 01/01/2021 - "Overall, our results provide an insight into SVMPs-induced toxicities and the promising protective efficacy of TTD can be extrapolated to treat severe tissue necrosis complementing anti-snake venom (ASV)." 03/01/2009 - "These results demonstrated that pig should be a useful animal model for the quantitation, pathogenesis and wound healing studies of snake venom induced local tissue necrosis, and for the search for effective treatment modality." 03/01/2009 - "Pig as an experimental model for the study of snake venom induced local tissue necrosis." 11/01/2023 - "Proteomic characteristics of six snake venoms from the Viperidae and Elapidae families in China and their relation to local tissue necrosis." 11/05/2021 - "The analysis of cell death shows that snake venom dominantly leads cells to necrosis. "

Related Drugs and Biologics

1.	Antivenins (Antivenoms)
2.	Proteins (Proteins, Gene)
3.	Venoms
4.	Metalloproteases (Metalloproteinases)
5.	Disintegrins
6.	Amino Acids
7.	Enzymes
8.	Fibrinogen (Factor I)
9.	Peptides (Polypeptides)
10.	Integrins

Related Therapies and Procedures

1.	Therapeutics
2.	First Aid (Aids, First)
3.	Intravenous Administration
4.	Length of Stay
5.	Mesotherapy