Snake Venoms (Snake Venom)

Solutions or mixtures of toxic and nontoxic substances elaborated by snake (Ophidia) salivary glands for the purpose of killing prey or disabling predators and delivered by grooved or hollow fangs. They usually contain enzymes, toxins, and other factors.

Also Known As:

Networked: 667 relevant articles (12 outcomes, 69 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Gutiérrez, José María: 18 articles (04/2015 - 11/2003)
2.	Soares, Andreimar M: 17 articles (01/2015 - 06/2002)
3.	Fox, Jay W: 13 articles (04/2015 - 03/2003)
4.	Rucavado, Alexandra: 12 articles (04/2015 - 11/2003)
5.	Sampaio, Suely V: 11 articles (01/2016 - 12/2004)
6.	Escalante, Teresa: 11 articles (04/2015 - 11/2003)
7.	Gutiérrez, J M: 10 articles (07/2013 - 02/2000)
8.	Lomonte, Bruno: 8 articles (11/2014 - 12/2002)
9.	Song, Ho Sueb: 7 articles (09/2015 - 02/2007)
10.	Park, Mi Hee: 7 articles (09/2015 - 02/2007)

Related Diseases

1.	Snake Bites (Snake Bite) 06/01/2013 - "To demonstrate that use of lower doses of anti-snake venom is as effective as high doses and is associated with less complications and lower mortality especially in the wake of rising cost of medical treatment, the people most affected by snakebites being the poor farmers. " 06/01/2013 - "High or low- a trial of low dose anti snake venom in the treatment of poisonous snakebites." 01/01/2010 - "This study points towards the importance of complete analysis of individual components of snake venom in order to develop effective therapies for snake bites." 01/01/2008 - "The purpose of this study was to determine the impact of a nationally developed snakebite treatment protocol on the amount of anti snake venom (ASV) used in treating snakebites in a developing country and its effect on mortality. " 10/01/2004 - "Rational use of anti-snake venom (ASV): trial of various regimens in hemotoxic snake envenomation."
2.	Wounds and Injuries (Trauma) 01/01/2015 - "One of the main challenges in toxicology today is to develop therapeutic alternatives for the treatment of snake venom injuries that are not efficiently neutralized by conventional serum therapy. " 01/01/2014 - "Besides antivenom, literature has described plants able to inhibit injuries and lethal activities induced by snake venoms. " 01/01/2013 - "In conclusion, promutoxin can induce accumulation of mast cells, which may contribute to snake-venom wound." 01/01/2011 - "These results demonstrate that the protein/peptide derived from snake venoms promotes healing of skin wounds. " 11/01/2009 - "Wound exudate as a proteomic window to reveal different mechanisms of tissue damage by snake venom toxins."
3.	Edema 01/01/2014 - "glomerata extract at proportions of 1:1, 1:2, and 1:4. Histopathological and morphometric analysis showed that intradermal administration of snake venom incubated with the hydroalcoholic extract at proportions of 1:1, 1:2 and 1:4 promoted a significant reduction in the number of inflammatory cells and a marked decrease in edema after the third hour. " 12/01/2015 - "In this study, we evaluated the edema and hyperalgesic response induced by BpirMP, a P-I class metalloproteinase isolated from Bothrops pirajai snake venom. " 10/01/2007 - "The present study investigates the supposed advantage of using an association of anti-inflammatory drugs and serum therapy to treat mouse paw edema induced by injection of Bothrops jararaca snake venom (BjV). " 01/01/1999 - "A study of hemorrhagic, edema-forming, proteolytic and myonecrotic activities induced by newborn Bothrops alternatus snake venoms from Argentina was performed. " 03/01/2015 - "Snake venom LAAOs have been reported to exhibit a wide range of pharmacological activities, including cytotoxic, edema-inducing, platelet aggregation-inducing/platelet aggregation-inhibiting, bactericidal and antiviral activities. "
4.	Inflammation 04/01/2009 - "In the present study, the progression of local tissue damage and inflammation induced by BnSP-7, a myotoxin isolated from Bothrops (neuwiedi) pauloensis snake venom, was evaluated. " 04/01/2010 - "Recently, promutoxin, a novel member of minor subgroup of snake venom PLA(2) (R49 PLA(2)) has been characterized in our laboratory, but its roles in induction of inflammation remain uninvestigated. " 03/15/2009 - "Our data suggest that 7-HOC interacts with sPLA2 and causes some structural modifications that lead to a sharp decrease or inhibition of the edematogenic and myotoxic activities of this enzyme, indicating its potential use to suppress inflammation induced by sPLA2 from the snake venom." 08/04/1992 - "In contrast to the in vitro results, anti-inflammatory activity was observed in all tests, except when inflammation was induced by snake venom PLA2. " 04/01/2010 - "Provocation of microvascular leakage and mast cell activation by promutoxin suggests further that snake venom induced inflammation is related to mast cell activation and certain anti-inflammatory drugs could be therapeutic effective in treating snake wound."
5.	Glioblastoma (Glioblastoma Multiforme) 01/01/2003 - "Contortrostatin (CN), a homodimeric snake venom disintegrin, has previously been demonstrated to be effective in blocking vitronectin/fibronectin-dependent adhesion and invasion of T98G human glioblastoma cells through Matrigel using in vitro studies. "

Related Drugs and Biologics

1.	Antivenins (Antivenoms)
2.	Metalloproteases (Metalloproteinases)
3.	contortrostatin
4.	Immunoglobulin G (IgG)
5.	Proteins (Proteins, Gene)
6.	Fibronectins (Fibronectin)
7.	Vitronectin
8.	matrigel
9.	Fibrinogen (Factor I)
10.	Silicon Dioxide (Sand)

Related Therapies and Procedures

1.	Premedication
2.	Ligation
3.	Therapeutics
4.	First Aid (Aids, First)
5.	Traditional Medicine (Folk Remedies)