Simethicone

02/24/2021 - "breve CECT7263 is a safe and effective treatment for infantile colic, presenting an earlier and more robust effect than the reference prescribed drug, simethicone."
01/01/2012 - "To compare the efficacy of Mentha piperita with simethicone in treatment for infantile colic. "
01/01/2007 - "reuteri improved colicky symptoms in breastfed infants within 1 week of treatment, compared with simethicone, which suggests that probiotics may have a role in the treatment of infantile colic."
07/01/1994 - "To determine the efficacy of simethicone in the treatment of infant colic. "
01/01/1988 - "The efficacy of simethicone (available in liquid form as Mylicon Drops) in the treatment of infant colic was assessed in 51 healthy infants between 2 and 12 weeks of age. "

11/03/2023 - "XG + PP showed a faster onset of action and a significant reduction in bloating and abdominal pain compared with simethicone. "
07/01/2016 - "The simethicone group showed superior cleansing results (6-9 Boston scale scores: 99% vs. 84%, <5% bubble scores: 96% vs. 49%, P < 0.001) and fewer gastrointestinal symptoms (abdominal fullness: 24% vs. 55%, colicky pain: 5% vs. 24%, P < 0.001) than the non-simethicone group. "
05/28/2014 - "Alverine, in combination with simethicone, has been demonstrated to effectively reduce abdominal pain and discomfort in a large placebo-controlled trial. "
01/01/2011 - "In a double-blind, randomized, placebo-controlled study enrolled 412 patients with IBS conform to Rome criteria III. Selection criterion in the study was to evaluate the intensity of abdominal pain or discomfort during the 2-week run-in period without medication, which according to analog scale (VAS) was to be 60-100 mm. With the help of an interactive voice communication system (IVCS), patients were randomized to treatment with either alverin citrate 60 mg with Simethicone 300 mg three times daily or corresponding placebo for 4 weeks. "
12/01/2019 - "Furthermore, simethicone decreases abdominal bloating but has no effect on nausea, vomiting, and abdominal pain. "

01/01/2019 - "The patients assessed their symptoms using the dyspepsia Global Overall Symptom scale at baseline, week 2, and week 4. After stopping medication for 2 weeks, the patients assessed recurrent symptoms and day of recurrence by themselves at the end of week 6. Results: In total, 78 patients underwent randomization (27 in 750 mg Curcuma longa, 26 in 1500 mg Curcuma longa, and 25 in simethicone groups). "
09/01/2002 - "To compare the efficacy of simethicone with placebo and the prokinetic cisapride in patients with functional dyspepsia. "
09/01/2002 - "A randomized placebo-controlled trial of simethicone and cisapride for the treatment of patients with functional dyspepsia."
09/01/2002 - "Simethicone and cisapride were significantly better than placebo for symptom control in patients with functional dyspepsia after 2, 4 and 8 weeks of treatment. "
09/01/2002 - "One hundred and eighty-five patients with functional dyspepsia were randomized and treated in a double-dummy technique with simethicone (105 mg t.d.s.), cisapride (10 mg t.d.s.) or placebo (t.d.s.). "

05/01/2019 - "The adjunction of oral simethicone significantly improved bowel preparation quality and might benefit adenoma detection in specific settings with low baseline ADR."
05/01/2019 - "However, the addition of simethicone improved adenoma detected per patient (2.20 ± 1.36 vs 1.63 ± 0.89) according to one of the included studies. "
01/01/2019 - "Combining simethicone (SIM) with a colon preparation agent has been shown to improve mucosal visibility during screening colonoscopy, but its effect on the adenoma detection rate (ADR) remains unclear. "
02/01/2019 - "Effect of supplemental simethicone for bowel preparation on adenoma detection during colonoscopy: A meta-analysis of randomized controlled trials."
01/01/2023 - "OSTs with simethicone achieved better endoscopic cleanliness, improving adenoma detection rate compared to the conventional PEG-AA protocol. "

01/01/2014 - "A randomized double-blind placebo-controlled clinical trial on efficacy and safety of association of simethicone and Bacillus coagulans (Colinox®) in patients with irritable bowel syndrome."
01/01/2020 - "We aimed to evaluate the efficacy and safety of PB+S (pinaverium bromide 100 mg plus simethicone 300 mg) in patients with irritable bowel syndrome (IBS). "
01/01/2013 - "Polar vectors as a method for evaluating the effectiveness of irritable bowel syndrome treatments: an analysis with pinaverium bromide 100mg plus simethicone 300mg po bid."
01/01/2020 - "Efficacy of the Combination of Pinaverium Bromide 100 mg Plus Simethicone 300 mg in Abdominal Pain and Bloating in Irritable Bowel Syndrome: A Randomized, Placebo-controlled Trial."
01/01/2011 - "[Efficacy of alverina citrate and simethicone combination in abdominal pain and discomfort of irritable bowel syndrome]."