Silver

Silver. An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.

Networked: 4235 relevant articles (221 outcomes, 564 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Percival, Steven L: 14 articles (12/2012 - 06/2007)
2.	Murugan, Kadarkarai: 10 articles (12/2015 - 03/2012)
3.	Walker, Michael: 10 articles (10/2014 - 09/2003)
4.	Panneerselvam, Chellasamy: 9 articles (12/2015 - 03/2013)
5.	Nicoletti, Marcello: 8 articles (12/2015 - 04/2015)
6.	Subramaniam, Jayapal: 8 articles (12/2015 - 03/2013)
7.	Benelli, Giovanni: 8 articles (12/2015 - 04/2015)
8.	Dinesh, Devakumar: 8 articles (12/2015 - 04/2015)
9.	Suresh, Udaiyan: 8 articles (12/2015 - 04/2015)
10.	Gurunathan, Sangiliyandi: 8 articles (01/2015 - 11/2009)

Related Diseases

1.	Wounds and Injuries (Trauma) 01/21/2009 - "This requires the ability to determine the efficacy of silver directly within the wound environment; an extremely complicated task that is difficult using classical (plate counting) microbiological assays because these cannot be conducted in situ. " 07/01/2014 - "crenulata was found to be very effective in wound repair and encourages harnessing the potentials of the plant biomolecules loaded silver nanoparticle in the treatment of tropical diseases including wound healing. " 09/01/2012 - "Although there was no observed difference in the number of women requiring additional wound care visits, the significantly greater number of comorbidities noted in the silver-impregnated dressing group should have theoretically placed them at increased risk for SSIs and additional postoperative wound care visits, suggesting that silver-impregnated dressings may have more of a protective effect than is appreciated in this study. " 05/01/2014 - "Furthermore, as compared to commercial wound gel Silver-Sept™, DispersinB(®)-KSL-W peptide-based wound gel was significantly more effective in inhibiting the biofilm-embedded MRSA, S. " 10/01/2013 - "In contrast, silver dressings improved healing in diabetic wounds despite no effect on bioburden, suggesting silver may have beneficial effects in addition to its antimicrobial properties."
2.	Infection 04/01/2013 - "In order to contain the risk of infections in clinical practice, there is a growing interest nowadays in silver-based products due to the strong antimicrobial efficacy of silver against a broad spectrum of microorganisms. " 05/31/2011 - "In conclusion, I. multifiliis infection induces liver and gill damage via lipid peroxidation products in silver catfish, but higher antioxidant enzyme activity could indicate a greater degree of protection against this parasite." 01/01/2014 - "Silver nanoparticles (AgNP)-loaded physical barriers were reported to be effective in anti-infection and anti-adhesion. " 12/01/2011 - "Efficacy of a total occlusive ionic silver-containing dressing combination in decreasing risk of surgical site infection: an RCT." 06/01/2009 - "There is limited evidence of efficacy of silver in preventing infection of short-term implantable medical devices."
3.	Burns 01/01/2013 - "Although silver dressings are the gold standard for burn care in Australasia, very few high-level trials have been conducted that compare silver dressings to determine which will provide the best level of care clinically. " 04/01/2015 - "The silver-impregnated foam dressing is effective and safe for use in partial-thickness paediatric burns, eliminating the need for daily dressings. " 04/01/2015 - "The silver-impregnated foam dressing is effective and safe for use in partial-thickness paediatric burns, eliminating the need for daily dressings." 07/01/1981 - "The efficacy of FPQC and FPQC silver in vivo may represent discovery of new agents of known low toxicity that are useful in topical burn therapy." 12/01/1998 - "Physico-chemical, pharmacological and microbiological data explaining the antimicrobial efficacy of silver in prophylaxis of implants are presented here, as well as the scientific background for the established clinical benefits of silver-preparations in burns."
4.	Ulcer 06/01/2010 - "In subjects with diabetic ulcers: after 4 weeks, the silver treatment was more effective than the control group treatment: Skin PO2 increased 2.6 times more than the control group (23.3% to 9.1%) and skin flux (RF) was significantly improved 4.3 times more than the control group(-26.7% to -6.2%). " 06/01/2010 - "The silver ointment improved microcirculation and the healing rate of all 78 patients that were treated with multivalent silver ointment and closed twice as many ulcers in 4 weeks compared to the control groups (40.7% silver treatment compared to 19.4% for the control). " 12/01/2014 - "In conclusion, this study suggests the superior performance of Biatain-Ag compared with the non silver-releasing dressing Biatain in particular for patients having ulcers associated with a poor healing prognosis. " 01/01/2013 - "The ulcer healing properties of the silver releasing foam dressing Biatain Ag has been examined in 4 randomized controlled trials (RCTs). " 01/01/2007 - " data from these trials show that silver-containing foam dressings did not significantly increase complete ulcer healing as compared with standard foam dressings or best local practice after up to four weeks of follow-up, although a greater reduction of ulcer size was observed with the silver-containing foam. "
5.	Urinary Tract Infections (Urinary Tract Infection) 01/01/2000 - "A prospective, controlled, randomized study of the effect of a slow-release silver device on the frequency of urinary tract infection in newly catheterized patients." 06/19/2013 - "We show both in vitro and in a mouse model of urinary tract infection that the ability of silver to induce oxidative stress can be harnessed to potentiate antibiotic activity. " 04/01/2009 - "Antibacterial effects of silver nanoparticles on the bacterial strains isolated from catheterized urinary tract infection cases." 03/01/1993 - "[Clinical study on efficacy of a Foley catheter coated with silver-protein in prevention of urinary tract infections]." 12/01/2010 - "Our results do not support a role for silver urinary catheters to prevent catheter associated urinary tract infection by decreasing bacterial adherence."

Related Drugs and Biologics

1.	Sulfadiazine (Sulphadiazine)
2.	alginic acid (sodium alginate)
3.	Ions
4.	Silver Sulfadiazine (SSD)
5.	Alloys
6.	Polyesters
7.	Rifampin (Rifampicin)
8.	nucleolar organizer region associated proteins
9.	Carboxymethylcellulose Sodium (Polycell)
10.	Copper

Related Therapies and Procedures

1.	Catheters
2.	Transplants (Transplant)
3.	Prostheses and Implants (Prosthesis)
4.	Negative-Pressure Wound Therapy
5.	Debridement