Silver

An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.

Networked: 8048 relevant articles (481 outcomes, 1211 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Gurunathan, Sangiliyandi: 24 articles (09/2019 - 11/2009)
2.	Benelli, Giovanni: 20 articles (04/2018 - 04/2015)
3.	Percival, Steven L: 19 articles (05/2022 - 06/2007)
4.	Murugan, Kadarkarai: 19 articles (01/2022 - 03/2012)
5.	Baldisserotto, Bernardo: 18 articles (10/2020 - 05/2014)
6.	Nicoletti, Marcello: 15 articles (06/2016 - 04/2015)
7.	Panneerselvam, Chellasamy: 15 articles (06/2016 - 03/2013)
8.	Chaudhry, Sarwat I: 14 articles (01/2022 - 11/2014)
9.	Kim, Jin-Hoi: 14 articles (09/2019 - 01/2013)
10.	Subramaniam, Jayapal: 14 articles (06/2016 - 03/2013)

Related Diseases

1.	Wounds and Injuries (Trauma) 01/21/2009 - "This requires the ability to determine the efficacy of silver directly within the wound environment; an extremely complicated task that is difficult using classical (plate counting) microbiological assays because these cannot be conducted in situ. " 10/12/2023 - "As a result, such silver-based dressing achieves potent therapeutic efficacy on infected wounds with excellent biosafety." 07/01/2014 - "crenulata was found to be very effective in wound repair and encourages harnessing the potentials of the plant biomolecules loaded silver nanoparticle in the treatment of tropical diseases including wound healing. " 09/01/2012 - "Although there was no observed difference in the number of women requiring additional wound care visits, the significantly greater number of comorbidities noted in the silver-impregnated dressing group should have theoretically placed them at increased risk for SSIs and additional postoperative wound care visits, suggesting that silver-impregnated dressings may have more of a protective effect than is appreciated in this study. " 01/01/2020 - "Finally, school zones and silver zones, which are representative policies for pedestrian safety in South Korea, fail to play a significant role in reducing the severity of pedestrian injuries. "
2.	Infections 10/01/2016 - "Silver-coated megaprostheses showed promising results in this series in terms of prevention of infection in a high-risk group of patients, many of whom had a history of infection. " 04/01/2013 - "In order to contain the risk of infections in clinical practice, there is a growing interest nowadays in silver-based products due to the strong antimicrobial efficacy of silver against a broad spectrum of microorganisms. " 02/01/2021 - "The developed silver-decorated Soluplus® nanoparticles were effective against biofilm infections and have the potential to be applied for other biofilm-related diseases. " 08/12/2014 - "Silver nanoparticles (AgNP)-loaded physical barriers were reported to be effective in anti-infection and anti-adhesion. " 01/01/2020 - "Silver nanoparticles (AgNPs) can be useful in the treatment of the UPEC infections due to its physicochemical properties that confer them antibacterial activity against both planktonic and biofilm structured cells. "
3.	Burns 11/25/2013 - "Although silver dressings are the gold standard for burn care in Australasia, very few high-level trials have been conducted that compare silver dressings to determine which will provide the best level of care clinically. " 01/01/2017 - "We sought to compare the efficacy of commonly used silver delivery approaches including nanocrystalline silver, silver-impregnated hydrofiber dressing, and silver-impregnated foam dressing as the main products in the management of partial thickness burns. " 04/01/2015 - "The silver-impregnated foam dressing is effective and safe for use in partial-thickness paediatric burns, eliminating the need for daily dressings. " 12/01/1998 - "Physico-chemical, pharmacological and microbiological data explaining the antimicrobial efficacy of silver in prophylaxis of implants are presented here, as well as the scientific background for the established clinical benefits of silver-preparations in burns." 01/01/2023 - "In this study, decellularized fish skin (DFS) scaffold decorated with silver nanoparticles was prepared for accelerating burn wound healing. "
4.	Neoplasms (Cancer) 04/05/2023 - "The successful performance of the SERS biosensor based on silver dendrites in this study promises to be effective in diagnostic applications such as cancer diagnosis (the limit of single molecular detection)." 01/01/2023 - "ZnO-Ag-NPs showed significantly greater efficacy in inhibiting cancer cell growth at a lower concentration of 31.25 μg/mL, compared to ZnO-NPs which required over 500 μg/mL, possibly due to the presence of silver nanoparticles (Ag-NPs). " 04/01/2018 - "Exploiting fruit byproducts for eco-friendly nanosynthesis: Citrus × clementina peel extract mediated fabrication of silver nanoparticles with high efficacy against microbial pathogens and rat glial tumor C6 cells." 01/01/2018 - "as green synthesized silver nanoparticles (G-AgNPs), in order to raise potential therapeutic efficacy, even up to two-fold higher than cis-platin, is going to play a crucial role in cancer treatment and could be considered as a new insight in this field. " 11/21/2022 - "An effective treatment of cancer may require a multi-target strategy with multi-step inhibition of signaling pathways that regulate CSCs and the TME, in lieu of the long-standing pursuit of a 'silver-bullet' single-target approach."
5.	Ulcer 06/01/2010 - "In subjects with diabetic ulcers: after 4 weeks, the silver treatment was more effective than the control group treatment: Skin PO2 increased 2.6 times more than the control group (23.3% to 9.1%) and skin flux (RF) was significantly improved 4.3 times more than the control group(-26.7% to -6.2%). " 02/05/2018 - "Our study demonstrated the efficiency of Aloe vera and silver nanoparticles in enhancing ulcer healing after irradiation." 12/01/2014 - "In conclusion, this study suggests the superior performance of Biatain-Ag compared with the non silver-releasing dressing Biatain in particular for patients having ulcers associated with a poor healing prognosis. " 01/01/2013 - "The ulcer healing properties of the silver releasing foam dressing Biatain Ag has been examined in 4 randomized controlled trials (RCTs). " 01/24/2007 - " data from these trials show that silver-containing foam dressings did not significantly increase complete ulcer healing as compared with standard foam dressings or best local practice after up to four weeks of follow-up, although a greater reduction of ulcer size was observed with the silver-containing foam. "

Related Drugs and Biologics

1.	Sulfadiazine (Sulphadiazine)
2.	Ions
3.	Silver Sulfadiazine (SSD)
4.	Alginates
5.	Gold
6.	Anti-Bacterial Agents (Antibiotics)
7.	Hydrogels
8.	Collagen
9.	Copper
10.	Solutions

Related Therapies and Procedures

1.	Catheters
2.	Therapeutics
3.	Urinary Catheters
4.	Prostheses and Implants (Prosthesis)
5.	Negative-Pressure Wound Therapy