Silicone Oils

Organic siloxanes which are polymerized to the oily stage. The oils have low surface tension and density less than 1. They are used in industrial applications and in the treatment of retinal detachment, complicated by proliferative vitreoretinopathy.

Also Known As:

Networked: 1853 relevant articles (111 outcomes, 176 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Rizzo, Stanislao: 10 articles (07/2022 - 05/2005)
2.	Yang, Chung-May: 10 articles (09/2021 - 01/2004)
3.	Flynn, Harry W: 9 articles (09/2022 - 07/2003)
4.	Chhablani, Jay: 8 articles (07/2021 - 05/2012)
5.	Arf, Serra: 8 articles (05/2021 - 01/2016)
6.	Hocaoglu, Mumin: 8 articles (05/2021 - 01/2016)
7.	Karacorlu, Murat: 8 articles (05/2021 - 01/2016)
8.	Sayman Muslubas, Isil: 8 articles (05/2021 - 01/2016)
9.	Wong, David: 8 articles (01/2017 - 03/2006)
10.	Nawrocki, Jerzy: 8 articles (01/2013 - 01/2002)

Related Diseases

1.	Retinal Detachment (Retinal Detachments) 01/01/2022 - "Silicone oil versus gas tamponade for primary rhegmatogenous retinal detachment treated successfully with a propensity score analysis: Japan Retinal Detachment Registry." 07/01/1991 - "Because many complicated cases of retinal detachment can also be treated successfully with gas tamponade, silicone oil should remain the last step in retinal detachment surgery." 01/01/1990 - "Because many complicated cases of retinal detachment can also be treated successfully with gas tamponade, silicone oil should remain the last option in retinal detachment surgery." 07/01/2018 - "Although the use of silicone oil has improved the results of retinal detachment surgery, its removal is recommended due to the ocular complications related to its long term use. " 01/01/1996 - "Silicone oil tamponade was effective for the treatment of retinal detachments with proliferative vitreo-retinopathy. "
2.	Retinal Perforations 09/01/2018 - "There are reports on good efficacy of silicone oil tamponade for primary and recurrent macular hole closure. " 11/01/1998 - "Silicone oil tamponade of macular holes is effective and safe. " 12/01/2015 - "The purpose of this research was to compare the efficacy of 360° and localized DLP in the management of macular-sparing RD in silicone oil-filled eyes with no detected retinal breaks. " 11/01/2007 - "To determine whether the efficacy of re-operation for idiopathic full-thickness macular hole (FTMH) remaining open after initial surgery with internal limiting membrane (ILM) peeling is correlated with macular hole configuration as determined by optical coherence tomography (OCT), macular hole size, macular hole duration before the first operation, or type of tamponade (gas or silicone oil). " 04/01/2018 - "To study the outcomes of redo macular hole surgery using light silicone oil tamponade. "
3.	Glaucoma 05/01/2023 - "Both viscotrabeculotomy with anterior chamber irrigation and Ahmed glaucoma valve implantation are effective in lowering the intraocular pressure in glaucoma after silicone oil removal with viscotrabeculotomy with anterior chamber irrigation providing greater reduction, higher success rates, and minimal complications." 01/01/2020 - "PRéCIS:: Glaucoma drainage devices (GDDs) are effective for the management of silicone oil-induced glaucoma. " 01/01/2021 - "Slow coagulation transscleral cyclophotocoagulation (TSCPC) is an effective and safe glaucoma surgery in patients with medically uncontrolled silicone oil (SO)-induced glaucoma. " 03/01/2005 - "Our results raise doubts about the efficacy of TSCPC in the management of glaucoma in eyes retaining silicone oil. " 01/01/1992 - "The removal of silicone oil from eyes with secondary glaucoma resulted in an improvement in 68% of patients. "
4.	Proliferative Vitreoretinopathy 10/01/2014 - "Significant visual improvement with a low complication rate may be achieved in patients with advanced proliferative vitreoretinopathy or EMM under silicone oil." 05/01/2011 - "In this study, the FCVB was designed to mimic natural vitreous morphology, and evaluate its physiological functions compared with traditional silicone oil substitutes, in an established rabbit model of proliferative vitreoretinopathy. " 12/01/2023 - "Proliferative vitreoretinopathy (OR = 2.95, p = 0.03) and silicone oil tamponade (OR = 3.70 compared to gas, p = 0.05) were associated with EZ/IZ damage. " 11/01/2023 - "The silicone oil was successfully maintained within the globe; however, the final visual acuity was limited due to proliferative vitreoretinopathy. " 11/01/2023 - "Postoperatively, no sign of proliferative vitreoretinopathy was observed, and at 3 months, the silicone oil was removed. "
5.	Endophthalmitis (Ophthalmia) 01/01/2009 - "These results suggest that silicone oil tamponade might be beneficial in the treatment strategy of infectious endophthalmitis." 01/01/2003 - "These results suggest that silicone oil tamponade might be beneficial in the treatment strategy of severe endophthalmitis." 08/03/2023 - "This study aims to evaluate the use of a silicone oil tamponade in the surgical management of endophthalmitis. " 08/03/2023 - "Silicone oil as a tamponade has some potential benefits in the management of endophthalmitis. " 04/10/2023 - "We performed a literature review to describe the incidence, protective and predisposing factors, causative pathogens, management options, and prognosis of infectious endophthalmitis in silicone oil-filled eyes. "

Related Drugs and Biologics

1.	Retinaldehyde (Retinal)
2.	Ganciclovir (Cytovene)
3.	Anti-Bacterial Agents (Antibiotics)
4.	Dexamethasone (Maxidex)
5.	Gases
6.	Sulfur Hexafluoride
7.	Hyaluronic Acid (Hyaluronan)
8.	Silicones
9.	perflutren (octafluoropropane)
10.	densiron

Related Therapies and Procedures

1.	Vitrectomy
2.	Lasers (Laser)
3.	Light Coagulation
4.	Endotamponade
5.	Trabeculectomy (Trabeculoplasty)