Silicone Elastomers (SE 30)

Polymers of silicone that are formed by crosslinking and treatment with amorphous silica to increase strength. They have properties similar to vulcanized natural rubber, in that they stretch under tension, retract rapidly, and fully recover to their original dimensions upon release. They are used in the encapsulation of surgical membranes and implants.

Also Known As:

Networked: 438 relevant articles (10 outcomes, 35 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	van der Mei, Henny C: 4 articles (01/2014 - 03/2002)
2.	Busscher, Henk J: 4 articles (01/2014 - 03/2002)
3.	Zhang, Wayne W: 2 articles (04/2012 - 12/2006)
4.	Douek, Philippe: 2 articles (06/2008 - 01/2008)
5.	Huet, Laurent: 2 articles (06/2008 - 01/2008)
6.	Attia, Cherif: 2 articles (06/2008 - 01/2008)
7.	Serfaty, Jean Michel: 2 articles (06/2008 - 01/2008)
8.	Sulaiman, Abdulrazzaq: 2 articles (06/2008 - 01/2008)
9.	Holdsworth, David W: 2 articles (04/2008 - 03/2007)
10.	Huang, Wenhai: 1 article (03/2016)

Related Diseases

1.	Hemorrhage 01/01/2006 - "Soft, silicone rubber instead of rigid tubing virtually eliminated such early complications as bowel perforation or massive bleeding. " 03/01/1994 - "Although the association of subgaleal hemorrhage with the use of the metal cup vacuum extractor has clearly been documented, its association with the silicone elastomer version has not been previously reported. " 03/01/1994 - "Subgaleal hemorrhage in the newborn infant associated with silicone elastomer vacuum extractor." 02/01/1986 - "The cortical PO2 measured by means of an implanted silicone elastomer tube responded immediately to graded hemorrhage. " 09/01/1972 - "Control of post-splenic puncture hemorrhage with a silicone rubber plug."
2.	Ischemia 01/01/1991 - "An experimental model of brainstem ischemia was developed by embolization technique with cylindrical silicone rubber emboli in cats. " 01/01/1991 - "Acute unilateral renal ischemia was applied to four groups of ten adult male Wistar rats for a period of 60 min, followed by revascularisation for 0, 15, 30 or 60 min. The aorta was then clamped and Microfil was injected at a standard pressure to fill the renal vasculature. " 01/01/1972 - "The vascular pattern of the kidneys as visualized with silicone rubber injection shows a diffuse patchy ischemia throughout the kidney, which persists after release of the obstructed renal artery. " 01/01/1999 - "Silicone rubber microangiography provided an excellent three-dimensional method for defining the distribution of the vasculature of the normal and contusioned rat brain, and was helpful in elucidating the pathophysiology of post-traumatic ischemia and hemorrhages of the brain. " 11/01/1999 - "Therefore, silicone rubber microangiography was helpful for elucidating the pathophysiology of posttraumatic ischemia and hemorrhages in the spinal cord. "
3.	Cicatrix (Scar) 10/01/2010 - "This review briefly summarizes the existing literature regarding the silicone elastomer's mechanism of action on scars, the clinical trials regarding its efficacy, a description of some controversial points and contradicting evidence, and possible adverse effects of this treatment method. " 12/01/2009 - "Using digital cameras, photos of all patients were taken to evaluate scar depth and, in five patients, silicone rubber was used to make a microrelief impression of the scars. " 09/01/1985 - "Microfil casts showed small track defects at 48 hours resolving to a fine scar at 6 weeks. " 11/01/2007 - "The precise mechanism of action of silicone elastomer sheeting has not been defined, but clinical trials report that this device is safe and effective for the treatment and prevention of hypertrophic and keloid scars if worn over the scar for 12 to 24 hours per day for at least 2 to 3 months. " 11/01/2007 - "Additional controlled clinical trials with large patient populations may provide further evidence for the efficacy of silicone elastomer sheeting in the treatment and prevention of hypertrophic and keloid scars. "
4.	Neoplasms (Cancer) 01/01/1994 - "The tissue was cleared, and the tumor carefully removed and examined microscopically for traces of silicone rubber. " 08/01/1970 - "II. A microcirculatory study of the normal and tumor vessels of the liver with the use of perfused silicone rubber." 12/01/2006 - "The 28 cm long applicator has a flexible structure made of silicone rubber for easy passage into cavities with deep-seated tumors. " 06/01/2005 - "The development of ACF and tumors in rats treated with AOM were significantly reduced by SE (30 and 60 mg/kg). " 02/01/2001 - "The tumors were also examined histologically, and casts of the tumor vasculature were prepared with silicone rubber. "
5.	Inflammation 05/01/1995 - "Histopathologic studies have demonstrated microshards from silicone elastomer metatarsophalangeal joint implants in adjacent tissues in a setting of chronic inflammation and in inguinal lymph nodes. " 08/01/2010 - "Orbital inflammation as a late complication of frontalis silicone elastomer sling operation for congenital ptosis." 05/01/1996 - "We conclude that the acute inflammation is particle-type specific and that Silicone elastomer particles are acutely inflammatory." 01/01/1981 - "The silicone rubber noncycled chambers either developed no capsule or a very thin capsule without the acute inflammation observed with the cycled side. " 04/01/1982 - "Synovial and osseous inflammation in failed silicone-rubber prostheses."

Related Drugs and Biologics

1.	Polymers
2.	methyl salicylate (Linsal)
3.	Dexamethasone (Maxidex)
4.	Silicone Elastomers (SE 30)
5.	Polytetrafluoroethylene (Teflon)
6.	Carbon Monoxide
7.	Silicones
8.	baysilon (polydimethylsiloxane)
9.	Polyvinyl Chloride (PVC)
10.	Plastics

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Splints
3.	Sutures (Suture)
4.	Catheters
5.	Prostheses and Implants (Prosthesis)