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Sigmoid Neoplasms

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Tumors or cancer of the SIGMOID COLON.

Also Known As:

Cancer of the Sigmoid; Neoplasms, Sigmoid; Sigmoid Colon Cancer; Sigmoid Colon Neoplasms; Sigmoidal Cancer; Cancer, Sigmoid; Cancer, Sigmoid Colon; Colon Cancer, Sigmoid; Colon Neoplasms, Sigmoid; Neoplasm, Sigmoid; Neoplasm, Sigmoid Colon; Neoplasms, Sigmoid Colon; Sigmoid Colon Neoplasm; Sigmoid Neoplasm; Cancer of Sigmoid; Sigmoid Cancer

Networked: 248 relevant articles (14 outcomes, 5 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neoplasm Metastasis (Metastasis)
2.	Neoplasms (Cancer)
3.	Colonic Neoplasms (Colon Cancer)
4.	Pulmonary Embolism
5.	Multiple Myeloma

Experts

1.	Amagasa, Hidetoshi: 4 articles (11/2014 - 01/2006)
2.	Lee, Kang Young: 3 articles (08/2015 - 10/2008)
3.	Nagahama, Takeshi: 3 articles (11/2014 - 11/2011)
4.	Fukuda, Akira: 3 articles (11/2014 - 11/2011)
5.	Fujiya, Keiichi: 3 articles (11/2014 - 11/2011)
6.	Arai, Kuniyoshi: 3 articles (11/2014 - 11/2011)
7.	Hama, Naoki: 3 articles (11/2014 - 11/2010)
8.	Ganno, Hideaki: 3 articles (11/2014 - 11/2011)
9.	Ami, Katsunori: 3 articles (11/2014 - 11/2011)
10.	Kawamoto, Yasuyuki: 3 articles (07/2014 - 03/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Sigmoid Neoplasms:

1.	irinotecan (Camptosar)FDA LinkGeneric 08/01/2011 - "[A case of sigmoid colon cancer with temporary dysarthria associated with irinotecan]." 03/01/2003 - "We report a case in which low-dose CPT-11 chemotherapy was effective for metastatic liver tumor of sigmoid colon cancer. " 11/01/2008 - "[A case of advanced sigmoid colon cancer performed resection of liver metastases after long-term control by S-1 and CPT-11 combination chemotherapy]." 03/01/2002 - "We performed PMC-CPT-11 therapy (modified pharmacokinetic modulating chemotherapy plus irinotecan, or modified PMC) in a case of sigmoid colon cancer with local invasion and multiple hepatic metastases. " 03/01/2010 - "Chemoradiotherapy using UFT and Leucovorin, and chemotherapy consisting of S-1 and CPT-11 as an additional therapy may be effective for treating unresectable advanced sigmoid colon cancer."
2.	Fluorouracil (Carac)FDA LinkGeneric 03/01/1988 - "A 57-year-old female patient with recurrent sigmoid colon cancer was successfully treated with 5-FU and UFT for 8 years. " 03/01/1988 - "[A case of recurrent sigmoid colon cancer successfully treated with 5-FU and UFT]." 01/01/2015 - "A 60-year-old man with cancer of the sigmoid colon and initially unresectable CRLM received 11 cycles of hepatic arterial infusion chemotherapy with 5-fluorouracil (1500mg/week), after which CRLM was downstaged to resectable. " 10/01/2001 - "[A case of multiple liver metastases from sigmoid colon cancer effectively treated by hepatic intra-arterial administration of levoforinate and 5-fluorouracil]." 06/01/1995 - "A case of liver tumors metastasized by Sigmoid colon cancer was treated with intrahepatic arterial infusion of CDDP (10 mg) and 5-FU (250 mg) via subcutaneously implanted reservoir. "
3.	Leucovorin (Folinic Acid)FDA Link 10/01/2008 - "For the treatment of multiple liver metastases from sigmoid colon cancer, the administration of UFT(300 mg/day)and oral Leucovorin(75 mg/day)was initiated after a resection of the sigmoid colon. " 05/01/2006 - "[A case of hepatic metastases of sigmoid colon cancer which completely responded to systemic l-leucovorin/5-FU therapy and oral LV/UFT combination therapy]." 01/01/1997 - "The purpose of this phase II study was to evaluate the efficacy and toxicity of fluorouracil and high-dose leucovorin (5-FU/LV) with pelvic irradiation as adjuvant therapy for patients with macroscopical resected rectal or recto-sigmoid cancer. " 03/01/2010 - "Chemoradiotherapy using UFT and Leucovorin, and chemotherapy consisting of S-1 and CPT-11 as an additional therapy may be effective for treating unresectable advanced sigmoid colon cancer." 03/01/2010 - "[A case of effective chemotherapy using S-1 and CPT-11 following chemoradiotherapy with UFT and Leucovorin for unresectable advanced sigmoid colon cancer]."
4.	panitumumab (Vectibix)FDA Link 01/01/2013 - "We report the case of a 60-year-old Japanese man who developed ILD associated with panitumumab therapy (third-line therapy) for metastatic sigmoid colon cancer involving the liver, lymph nodes, and lungs. " 03/01/2014 - "[A case of curatively resected sigmoid colon cancer after mFOLFOX6 plus panitumumab neoadjuvant chemotherapy]." 03/01/2013 - "[A case of locally advanced sigmoid colon cancer curatively resected after neoadjuvant chemotherapy with FOLFIRI plus panitumumab]." 01/01/2014 - "A 73-year-old male with sigmoid colon cancer and synchronous lung metastasis was treated with panitumumab, an alone anti-EGFR monoclonal antibody as the third-line therapy.During" 09/01/2011 - "[A case of sigmoid colon cancer with liver and ovarian metastases effectively treated by panitumumab after acquiring resistance to prior chemotherapy regimens]."
5.	BariumIBA 10/01/1992 - "Sixty-six patients underwent further investigation, and 26 had positive results: colonic lesions were confirmed in 20 patients, sigmoid colon cancer was found on barium enema in one, and lesions outside the colon were detected in seven. " 06/01/2009 - "Barium enema and positron emission tomography-CT demonstrated sigmoid colon cancer. " 07/01/1993 - "A barium enema and an endoscopic examination disclosed sigmoid colon cancer. " 01/01/1985 - "The false-negative rate of barium enema examinations for the recognition of polypoid sigmoid cancer was evaluated in 167 patients with histologically proven carcinoma. " 01/01/1985 - "False-negative barium enema in patients with sigmoid cancer and coexistent diverticula."
6.	cetuximab (Erbitux)FDA Link 07/01/2014 - "[Successful treatment of advanced sigmoid colon cancer with liver metastases with cetuximab monotherapy as first-line treatment-a case report]." 07/01/2014 - "We report here the successful management of a case of advanced sigmoid colon cancer, with icterus due to severe liver metastases, treated with cetuximab as first-line therapy. " 05/01/2014 - "We report a case of a 55 year-old woman, diagnosed with stenosing sigmoid cancer and liver metastases, which underwent multimodal treatment: palliative surgery -Hartmann segmental colectomy, and adjuvant chemotherapy -second line monotherapy with cetuximab, according to standard protocols. "
7.	Biological Tumor Markers (Tumor Markers)IBA 01/01/2012 - "This represents a rare case of sigmoid colon cancer with high levels of tumor markers in sera that improved following sigmoidectomy without further anti-cancer treatment."
8.	Thalidomide (Thalomid)FDA Link 11/01/2009 - "Screening for cancer revealed coexistence of two neoplasms: colon sigmoid cancer (operated on 6 weeks after pulmonary embolism onset), and multiple myeloma (treated successfully with thalidomide and dexamethasone). "
9.	Starch (Cornstarch)IBA 10/01/2001 - "[Sigmoid colon cancer with multiple liver metastasis (H3) effectively treated with CPT-11 and DSM (degradable starch microsphere) HAI therapy and intensive high dosage 5-FU HAI therapy--a case report]." 10/01/2001 - "A weekly HAI therapy (CPT-11 80 mg, MMC 4 mg, degradable starch microsphere (DSM) 600 mg) was given to a patient with sigmoid colon cancer and multiple liver metastasis (H3) who had been taking tegafur 300 mg/day and 5-FU 750 mg HAI/week, which resulted in PD. "
10.	Interferon-gamma (Interferon, gamma)IBA 01/01/1995 - "We report herein the case of a 63-year-old man with cancer of the sigmoid colon and metastatic nodules in the liver who was effectively treated with a combination of cisplatin regional chemotherapy, given through the hepatic artery, in conjunction with a 3-week course of intravenous gamma-interferon (INF-gamma), following palliative sigmoidectomy and dissection of the regional lymph nodes. "

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 11/01/2012 - "Here we describe a case of sigmoid colon cancer (cStage IV) for which preoperative chemotherapy improved the outcome of surgery. " 11/01/2015 - "[A Case of Complete Pathological Response in a Patient with Locally Advanced Sigmoid Colon Cancer after FOLFOX IRI Chemotherapy]." 08/01/2013 - "[Case report of long-term survival obtained for advanced sigmoid colon cancer with para-aortic lymph nodes by resection and chemotherapy]." 01/01/2011 - "Following resection of the sigmoid colon cancer, mTEGAFIRI chemotherapy was administered. " 12/01/2010 - "We present a case of metastatic sigmoid colon cancer causing duodenal perforation during modified FOLFOX6 chemotherapy. "
2.	Colectomy 09/01/2013 - "The aim of this study is to determine whether single-port colectomy for sigmoid colon cancer is a safe and effective surgical option. " 09/01/2013 - "Safety and efficacy of single-port colectomy for sigmoid colon cancer: a phase II clinical trial." 03/01/2015 - "Laparoscopic sigmoid colectomy for a patient with sigmoid colon cancer and crossed-fused renal ectopia: a case report." 11/01/2014 - "A 71 year -old man underwent sigmoid colectomy for sigmoid colon cancer. " 01/01/2014 - "Laparoscopic versus open left colectomy in patients with sigmoid colon cancer: prospective cohort study with long-term follow-up."
3.	Enema (Enemas) 04/15/1995 - "Cancer of the sigmoid colon appears the main differential diagnosis, when diverticulitis is associated with an atypical or complete colonic stenosis on opaque enema, with a vesicoenteric fistula or with a peritonitis due to a colonic perforation. " 10/01/1992 - "Sixty-six patients underwent further investigation, and 26 had positive results: colonic lesions were confirmed in 20 patients, sigmoid colon cancer was found on barium enema in one, and lesions outside the colon were detected in seven. " 06/01/2009 - "Barium enema and positron emission tomography-CT demonstrated sigmoid colon cancer. " 07/01/1993 - "A barium enema and an endoscopic examination disclosed sigmoid colon cancer. " 01/01/1985 - "The false-negative rate of barium enema examinations for the recognition of polypoid sigmoid cancer was evaluated in 167 patients with histologically proven carcinoma. "
4.	Combined Modality Therapy 11/01/2013 - "[A case of Stage IV sigmoid colon cancer cured with radical combined modality therapy]." 07/01/2013 - "We report on a case of metastatic recurrence of sigmoid colon cancer in the Virchow lymph node with severe lymph node metastases successfully treated with a combined modality therapy of systemic chemotherapy and radiotherapy. " 05/01/2014 - "We report a case of a 55 year-old woman, diagnosed with stenosing sigmoid cancer and liver metastases, which underwent multimodal treatment: palliative surgery -Hartmann segmental colectomy, and adjuvant chemotherapy -second line monotherapy with cetuximab, according to standard protocols. "
5.	Microspheres (Microsphere) 10/01/2001 - "[Sigmoid colon cancer with multiple liver metastasis (H3) effectively treated with CPT-11 and DSM (degradable starch microsphere) HAI therapy and intensive high dosage 5-FU HAI therapy--a case report]." 10/01/2001 - "A weekly HAI therapy (CPT-11 80 mg, MMC 4 mg, degradable starch microsphere (DSM) 600 mg) was given to a patient with sigmoid colon cancer and multiple liver metastasis (H3) who had been taking tegafur 300 mg/day and 5-FU 750 mg HAI/week, which resulted in PD. "