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Senna Extract

Preparations of SENNA PLANT. They contain sennosides, which are anthraquinone type CATHARTICS and are used in many different preparations as laxatives.
Also Known As:
Extract, Senna; Folium, Sennae; Fructus, Sennae; Leaf, Senna; Pods, Senna; Senna Leaf; Senna Pods; Sennae Folium; Sennae Fructus
Networked: 39 relevant articles (2 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Li, Dan: 2 articles (01/2020 - 04/2019)
2. Cao, Jing: 2 articles (02/2018 - 06/2017)
3. Chen, Yaoxing: 2 articles (02/2018 - 06/2017)
4. Dong, Yulan: 2 articles (02/2018 - 06/2017)
5. Qin, Zhuoming: 2 articles (02/2018 - 06/2017)
6. Wang, Zixu: 2 articles (02/2018 - 06/2017)
7. Liu, Chunlian: 1 article (06/2022)
8. Liu, Yanju: 1 article (06/2022)
9. Shi, Kun: 1 article (06/2022)
10. Song, Chengcheng: 1 article (06/2022)

Related Diseases

1. Diarrhea
2. Constipation
3. Body Weight (Weight, Body)
01/01/2018 - "This study showed that the senna leaf decoction could induce diarrhea and dose-dependently slow body weight growth, reduce food consumption, and increase water intake, stool Bristol score, and defecation frequency. "
11/01/2008 - "Compared to those of the model group, Changan Granule could improve diarrhea induced by Folium Sennae and increase body weight obviously (P<0.05 or P<0.01). "
01/01/2018 - "Gastric gavage of 10 mL/kg of body weight of a high concentration of a senna leaf decoction (1.0 g/mL) for 4 weeks was used to create a rat model of diarrhea with spleen-kidney yang deficiency syndrome."
01/01/2018 - "Body weight monitoring, food consumption, water intake, defecation frequency, stool Bristol score, weight-loaded forced swimming test, forelimb grip strength test, D-xylose absorption test, serum cortisone, adrenocorticotropic hormone (ACTH), 24 h urine 17-hydroxycorticosteroid (17-OHCS), and histopathological detection were conducted to assess the success of the senna leaf decoction-induced model. "
06/21/2017 - "To explore the role of serotonin (5-HT) in weaning mice subjected to stress-induced diarrhea, 21-day-old weaned mice were divided into the following groups: control group, stress-induced diarrhea group (restrained by binding the hind limbs and intragastric administration of folium sennae with 0.4 g/mL, 15 mL/kg body weight) and para-chlorophenylalanine (PCPA) + stress-induced diarrhea group (30 mg/mL, 300 mg/kg body weight PCPA intraperitoneal injection before stress-induced diarrhea treatment). "
4. Hemorrhage
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Senna Extract
2. Proteins (Proteins, Gene)
3. Cecropins
4. Adenine
5. Antidiarrheals
6. Sennosides (Senokot)
7. Tea
8. Solutions
9. Hydrocortisone (Cortisol)
10. Enzymes

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Subcutaneous Injections
3. Intraperitoneal Injections
4. Enema (Enemas)