Self Mutilation

01/01/2022 - "The objective of this study was to explore the safety and efficacy of botulinum toxin (BoNT) injected into the masticatory muscles and biceps brachii to reduce self-mutilation in patients with LND. "
09/01/2005 - "Botulinum toxin as a novel treatment for self-mutilation in Lesch-Nyhan syndrome."
01/01/2021 - "Reduction of self-mutilating behavior and improved oromotor function in a patient with Lesch-Nyhan syndrome following botulinum toxin injection: A case report."
05/01/2008 - "Botulinum toxin: treatment of self-mutilation in patients with Lesch-Nyhan syndrome."
01/01/2021 - "This case report describes a 13-year-old boy with Lesch-Nyhan syndrome and self-mutilating behavior who received botulinum toxin injections to his bilateral masseter muscles after failing multiple other treatments. "

07/01/1996 - "Risperidone antagonism of self-mutilation in a Lesch-Nyhan patient."
05/01/1997 - "Remission of self-mutilation in a patient with borderline personality during risperidone therapy."
05/01/2001 - "[The effect of risperidone on the self-mutilation of Lesch-Nyhan syndrome]."
02/28/2018 - "In children and adolescents, risperidone is used for bipolar disorder, tic disorders, conduct disorder, schizophrenia, symptoms of irritability and self-mutilation. "
07/01/1996 - "2. Chronic treatment with the atypical neuroleptic risperidone at 4 mg daily has maintained a significant reduction in occurrence of self-mutilation."

02/01/1998 - "Upon maturation, animals were injected with L-dopa and placed in photocell cages for monitoring of locomotion, stereotypies, and self-mutilation. "
09/01/1984 - "Neonatal-6-OHDA treated rats given L-DOPA after a decarboxylase inhibitor showed a high incidence of self-mutilation behavior (SMB) and self-biting. "
02/01/1998 - "SCH-23390 eliminated L-dopa induced self-mutilation in all subjects, while risperidone eliminated self-mutilation in all but one subject."
01/10/1989 - "Clozapine also blocked the self mutilation resulting from L-dihydroxyphenylalanine (L-DOPA) administration to neonatal-6-OHDA-lesioned rats, an effect previously linked to D-1 receptor activation. "
11/01/1985 - "The present investigation supports the hypothesis that functionally supersensitive D-1 dopamine receptors are involved in the self-mutilation behavior (SMB) induced by L-dihydroxyphenylalanine (L-dopa) in rats treated neonatally with 6-hydroxydopamine (6-OHDA). "

01/01/2001 - "In clinical practice, antipsychotic medication is also used to control severe behavioral disturbances such as agitation, wandering, self-mutilation, as well as assaultiveness. "
11/01/2013 - "These findings indicate that inspection of the oral cavity should always and carefully be performed in all patients with mental retardation and in those with neuroleptic and anti-epileptic drug therapy, in order to avoid or even extinguish self-mutilation of the oral cavity by means of an accurate hydration of the mucosa which might counterbalance some iatrogenic undesired effects."
07/01/1996 - "2. Chronic treatment with the atypical neuroleptic risperidone at 4 mg daily has maintained a significant reduction in occurrence of self-mutilation."
01/01/2003 - "We describe the impact of the novel antipsychotic drug quetiapine on severe self-mutilation in two female patients with the diagnoses of BPD. "
01/01/2021 - "The first case involved the rare but debilitating condition of periodic catatonia, the second case involved the use of intranasal oxytocin to augment an antipsychotic for a patient with worsening psychotic symptoms (and a prior diagnosis of schizophrenia) in the postpartum period, and the third case involved auto-enucleation (often referred to as "Oedipism"), a violent form of self-mutilation, in a patient presenting with first-episode schizophrenia. "

05/01/2014 - "This review suggests that clozapine may be a beneficial treatment option for BPD especially in controlling symptom severity, psychotic symptoms, impulsivity, self-mutilation, number of days on enhanced observation, use of restraint, and overall functioning."
07/01/1999 - "After clozapine treatment, there were statistically significant reductions in incidents of self-mutilation (restraint), seclusion, the use of p.r.n. "
07/01/1999 - "These subjects had been admitted to 2 state psychiatric hospitals owing to severe self-mutilation and/or violence and subsequently treated with clozapine. "
07/01/1999 - "Clozapine reduces severe self-mutilation and aggression in psychotic patients with borderline personality disorder."
07/01/1999 - "These preliminary but nonetheless favorable results suggest that clozapine deserves careful consideration for a controlled study in patients with borderline personality disorder and psychoses, especially if the clinical issues include severe self-mutilation, aggression, and violence. "

01/01/2008 - "This study strongly supports the assumption that patients with DD are at high risk for self-mutilating behavior and points to the necessity of routine screening for self-mutilating behavior as well as the hypnotic capacity which may constitute a high risk for self-injury in this patient group."
01/01/2008 - "Innate hypnotic capacity was a strong predictor of self-mutilating behavior in DD patients. "
01/01/2008 - "Self-mutilating behavior in patients with dissociative disorders: the role of innate hypnotic capacity."
01/01/2008 - "Fifty patients diagnosed with DD and 50 control subjects with major depression were assessed by using a self-mutilation questionnaire, Dissociative Experiences Scale, Traumatic Experiences Checklist, and the Eye-Roll Sign for their self-mutilating behaviors, dissociative symptoms, early trauma, and innate hypnotic capacity, respectively. "
07/01/1976 - "5-HTP produced a significant reduction of athetoid movement and a sedative effect but did not improve the patient's mood or reduce self-mutilation."

01/01/1991 - "The delayed onset of the autotomy behavior after locally administered anesthetics suggests that the lesion-induced afferent barrage modified self-mutilation. "
01/01/2004 - "The aim of this study was to determine the effect of different anesthetic agents, and of pre-rhizotomy nociceptive stimulation on the appearance of self-mutilation. "

11/01/1996 - "Two patients had increased self-mutilation when carbamazepine was stopped, then improved a second time when treatment was restarted. "
11/01/1996 - "Carbamazepine trial for Lesch-Nyhan self-mutilation."
11/01/1996 - "We performed nerve and muscle biopsies on four patients with Lesch-Nyhan syndrome and initiated an uncontrolled pilot trial to see if carbamazepine would reduce the self-mutilation in these patients. "

10/01/1994 - "Naltrexone was used successfully in controlling self-mutilation behavior in 3 zoo animals from 2 families (Felidae and Sciuridae). "
01/01/1997 - "Cessation of self-mutilation in a patient with borderline personality disorder treated with naltrexone."
01/15/1993 - "Naltrexone, an opioid antagonist recently advocated for the control of stereotypic behavioral patterns in horses and dogs, induced an intense dose-related pruritic reaction in a dog with tail-chasing and self-mutilating behavior. "
07/01/1993 - "Obesity and self-mutilation are discussed with regard to the use of fluoxetine and naltrexone."
01/01/2020 - "Our purpose is to analyze the evidence on the efficacy of the use of buprenorphine, nalmefene, naloxone and naltrexone, in the treatment of dissociative symptoms, self-mutilation and suicidal behavior of these patients. "

05/01/2008 - "We here report the case of a 30-year-old man with a confirmed diagnosis of LNS who was successfully treated for self-mutilation of his lips with repeated botulinum toxin A (BTX-A) injections in the facial perioral muscles. "
09/01/2005 - "This report describes a 10-year-old male child with confirmed LNS who was treated for self-mutilation of his hands, tongue, and lips with repeated botulinum toxin A (BTX-A) injections into the bilateral masseters. "
08/01/2022 - "The oral pathology team considered that the most appropriate therapy was botulinum toxin A injections along with therapeutic adjustment, which was effective in wound healing and self-mutilation behavior ceasing at the two-month follow-up."
07/01/2014 - "Self-mutilation of the lower lip in a child with dystonia secondary to megalencephalic leukoencephalopathy treated with botox injections: a case report."

03/01/1984 - "[Self mutilation of the tongue in a child: trial therapy apropos of a case]."
01/01/2006 - "At admission, the frequency of self-mutilating behavior and the amount of inpatient treatment (an average of 68 days annually) of the sample was high, characterizing this patient group as "previously therapy resistant." Treatment outcome was assessed both at the end of treatment and in a 1-year follow-up. "
02/01/2003 - "Dialectical behaviour therapy resulted in better retention rates and greater reductions of self-mutilating and self-damaging impulsive behaviours compared with usual treatment, especially among those with a history of frequent self-mutilation. "
05/01/1997 - "Finally, depending on the direction of delinquency-either directed against oneself or against others-various therapy requirements are outlined: delinquency in the sense of self-mutilation primarily requires the team to perform a holding function, while aggressive delinquency primarily demands a firm setting. "
09/01/1987 - "In 18 therapy sessions over 6 weeks in a psychiatric inpatient setting she achieved complete control of the self-mutilating behavior. "

01/01/1991 - "Bupivicaine injections into the cingulum produced a significant delay in the onset of self-mutilation and reduced the overall degree of autotomy. "
11/01/2012 - "A five- year- old boy, born to second-degree consanguineous parents after uneventful antenatal period, presented to us with history of recurrent unexplained fever, recurrent ulcers in the lower limbs, insensitivity to painful stimuli (like injections, vaccination) and self-mutilating behavior from early childhood. "
05/01/2008 - "We here report the case of a 30-year-old man with a confirmed diagnosis of LNS who was successfully treated for self-mutilation of his lips with repeated botulinum toxin A (BTX-A) injections in the facial perioral muscles. "
09/01/2005 - "This report describes a 10-year-old male child with confirmed LNS who was treated for self-mutilation of his hands, tongue, and lips with repeated botulinum toxin A (BTX-A) injections into the bilateral masseters. "
08/01/2022 - "The oral pathology team considered that the most appropriate therapy was botulinum toxin A injections along with therapeutic adjustment, which was effective in wound healing and self-mutilation behavior ceasing at the two-month follow-up."

02/01/2007 - "At present tattoos and piercings can no longer be regarded as destructive acts of self mutilation practized by fringe groups. "
07/01/1999 - "To assess seroprevalence of human immunodeficiency virus (HIV), hepatitis C virus, injecting drug use, unsafe sexual behaviours, self-mutilation and tattoos in patients attending a drug and alcohol treatment centre in Japan. "
06/01/1990 - "Self-tattooing as an action of autoaggressive self-mutilation or self-destruction is not always necessarily psychotic in nature; it may also be found in patients in whom a depressive personality structure is accompanied by strong masochistic tendencies at a neurotic level. "
06/01/1990 - "Self-tattooing is a form of self-mutilation and may sometimes come close to an 'artefact'. "
06/01/1990 - "[Tattooing and self-mutilation of the skin in neurotic character disorder]."

02/01/2023 - "[Conservative therapy after self-mutilation of the scrotum resulting in bilateral testicular underperfusion]."
01/01/2009 - "Failure of conservative treatment in self-mutilation injuries often leads to toe or limb amputation as a last resort. "
01/01/2021 - "Botulinum toxin injections to the masseters may help to improve oromotor function and reduce self-mutilating behaviors in children with Lesch-Nyhan syndrome who have failed more conservative treatments, providing opportunity for improved functional status and patient safety. "

12/01/2001 - "Improvement in severe self-mutilation following limbic leucotomy: a series of 5 consecutive cases."
12/01/2002 - "Limbic leucotomy in self-mutilation."
12/01/2001 - "We report the effects of limbic leucotomy in 5 consecutive patients with severe self-mutilation behaviors. "
12/01/2001 - "In carefully selected patients as described in this report, limbic leucotomy may be an appropriate therapeutic consideration for self-mutilation associated with severe, intractable psychiatric disorders."