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Seizures (Absence Seizure)

Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or "seizure disorder."
Also Known As:
Absence Seizure; Focal Seizures; Tonic-Clonic Seizures; Seizure, Absence; Atonic Absence Seizures; Atonic Seizures; Clonic Seizures; Complex Partial Seizures; Convulsion, Non-Epileptic; Generalized Absence Seizures; Myoclonic Seizures; Non-Epileptic Seizures; Nonepileptic Seizures; Partial Seizures; Petit Mal Convulsion; Seizures, Auditory; Seizures, Clonic; Seizures, Epileptic; Seizures, Gustatory; Seizures, Olfactory; Seizures, Somatosensory; Seizures, Tonic; Seizures, Tonic-Clonic; Seizures, Vertiginous; Seizures, Vestibular; Seizures, Visual; Single Seizure; Tonic Seizures; Absence Seizure, Atonic; Absence Seizure, Generalized; Absence Seizures, Atonic; Absence Seizures, Generalized; Auditory Seizure; Auditory Seizures; Clonic Seizure, Tonic; Clonic Seizures, Tonic; Convulsion, Non Epileptic; Convulsion, Petit Mal; Convulsions, Non-Epileptic; Focal Seizure; Generalized Seizure; Generalized Seizures; Generalized Tonic Clonic Seizures; Generalized Tonic-Clonic Seizure; Gustatory Seizure; Gustatory Seizures; Motor Seizure; Motor Seizures; Non Epileptic Seizure; Non Epileptic Seizures; Non-Epileptic Convulsion; Non-Epileptic Convulsions; Olfactory Seizure; Olfactory Seizures; Partial Seizure, Complex; Partial Seizures, Complex; Seizure, Atonic; Seizure, Atonic Absence; Seizure, Auditory; Seizure, Clonic; Seizure, Complex Partial; Seizure, Convulsive; Seizure, Epileptic; Seizure, Focal; Seizure, Generalized; Seizure, Generalized Absence; Seizure, Generalized Tonic-Clonic; Seizure, Gustatory; Seizure, Jacksonian; Seizure, Motor; Seizure, Myoclonic; Seizure, Non-Epileptic; Seizure, Nonepileptic; Seizure, Olfactory; Seizure, Partial; Seizure, Sensory; Seizure, Single; Seizure, Somatosensory; Seizure, Tonic; Seizure, Tonic Clonic; Seizure, Tonic-Clonic; Seizure, Vertiginous; Seizure, Vestibular; Seizure, Visual; Seizures, Generalized Tonic-Clonic; Seizures, Nonepileptic; Sensory Seizure; Sensory Seizures; Single Seizures; Somatosensory Seizure; Somatosensory Seizures; Tonic Clonic Seizures; Tonic-Clonic Seizure, Generalized; Tonic-Clonic Seizures, Generalized; Vertiginous Seizure; Vertiginous Seizures; Vestibular Seizure; Vestibular Seizures; Visual Seizure; Visual Seizures
Networked: 42887 relevant articles (3415 outcomes, 5069 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Seizures (Absence Seizure)
2. Epilepsy (Aura)
3. Status Epilepticus (Complex Partial Status Epilepticus)
4. Partial Epilepsies (Epilepsy, Partial)
5. Lennox Gastaut Syndrome

Experts

1. Löscher, Wolfgang: 109 articles (01/2022 - 01/2002)
2. Marson, Anthony G: 94 articles (01/2022 - 05/2002)
3. Czuczwar, Stanisław J: 87 articles (04/2022 - 01/2002)
4. Henshall, David C: 81 articles (01/2022 - 07/2002)
5. Striano, Pasquale: 79 articles (05/2022 - 01/2006)
6. Verrotti, Alberto: 76 articles (01/2022 - 04/2002)
7. O'Brien, Terence J: 75 articles (05/2022 - 09/2003)
8. Vezzani, Annamaria: 74 articles (01/2022 - 01/2002)
9. Holmes, Gregory L: 73 articles (01/2022 - 01/2002)
10. Russo, Emilio: 72 articles (06/2022 - 02/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Seizures:
1. Anticonvulsants (Antiepileptic Drugs)IBA
2. Pharmaceutical PreparationsIBA
3. Valproic Acid (Depakote)FDA LinkGeneric
4. Pentylenetetrazole (Metrazol)IBA
5. Levetiracetam (Keppra)FDA LinkGeneric
6. Carbamazepine (Tegretol)FDA LinkGeneric
7. Phenytoin (Dilantin)FDA LinkGeneric
8. Phenobarbital (Luminal)FDA Link
9. Lamotrigine (Lamictal)FDA LinkGeneric
10. Diazepam (Valium)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Ketogenic Diet
3. Vagus Nerve Stimulation
4. Electrodes (Electrode)
01/01/2022 - "Gold-standard seizure detections using multi-channels electroencephalograms (EEG) require trained clinical physiologists to apply scalp electrodes and highly specialised neurologists to interpret and identify seizures. "
08/01/1996 - "We have found intracerebral electrode placement to be as safe as subdural strip electrode placement and have found combined depth and strip electrode monitoring to be highly effective in localizing the onset zones of complex partial seizures. "
12/01/1991 - "Among these recent observations are findings that (1) generalized seizures that are "adequate" by conventional duration criteria may be produced reliably, yet lack therapeutic properties; (2) the degree to which stimulus intensity exceeds seizure threshold is critical in determining the efficacy of unilateral ECT and also the speed of response with both unilateral and bilateral ECT; (3) the degree to which electrical dose exceeds seizure threshold, not the absolute dose administered, determines dosing effects on clinical outcome and on the magnitude of cognitive deficits; (4) there is marked variability among patients in their seizure thresholds that is related reliably to patient characteristics (sex, age) and treatment factors (electrode placement); and (5) seizure duration alone should not serve as a marker of the adequacy of treatment--there are complex relations between stimulus dosing and seizure duration, with the likelihood that substantially suprathreshold stimulation may result in shorter durations particularly early in the treatment course."
11/03/2023 - "The initiation of seizures exclusively detected in hippocampal depth electrodes was associated with successful seizure remission, whereas those solely recorded in the lateral strip electrodes were often linked to refractory seizures after ATL. "
02/01/2011 - "Patients with extratemporal, nonlesional seizures are viable candidates for invasive monitoring with grid/strip electrodes, and good outcomes can be obtained with resective surgery. "
5. Drug Therapy (Chemotherapy)