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Secobarbital (Sebar)

Subscribe to New Research on Secobarbital

A barbiturate that is used as a sedative. Secobarbital is reported to have no anti-anxiety activity.

Also Known As:

Sebar; Seconal; Flynn Brand of Secobarbital Sodium; Ranbaxy Brand of Secobarbital Sodium; Secobarbital Sodium; Seconal Sodium; Vangard Brand of Secobarbital Sodium; Sodium, Secobarbital; Meballymal; Quinalbarbitone; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylbutyl)-5-(2-propenyl)-

Networked: 47 relevant articles (4 outcomes, 11 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 319
    - Pyrimidinones: 14
      - Barbiturates: 929
        Secobarbital: 47
        Tuinal: 2
        High Greran
        secobarbital drug combination hydroxyzine brallobarbital
        secopyrabital

Experts

1.	Gerhardt, Robert T: 1 article (01/2011)
2.	Pfaff, James: 1 article (01/2011)
3.	Hermstad, Erik: 1 article (01/2011)
4.	Crawford, Donald M: 1 article (01/2011)
5.	Rayfield, John: 1 article (01/2011)
6.	Hunter, Curtis J: 1 article (01/2011)
7.	Lewis, J: 1 article (07/2010)
8.	Streete, P: 1 article (07/2010)
9.	Williamson, S: 1 article (07/2010)
10.	Woodger, N: 1 article (07/2010)

Related Diseases

1.	Pain (Aches) 11/01/1980 - "A syndrome of severe upper extremity pain, swelling and weakness following intraarterial injection of illicit secobarbital was evaluated in 4 patients. " 01/01/2011 - "Secobarbital subjects reported an average headache pain decrease of 25 mm (-13 to -38) compared with an average increase of 3 mm (-13 to 19) in the placebo group (P = .01). " 01/01/2011 - "Postdischarge secobarbital after ED migraine treatment decreases pain and improves resolution." 01/01/2011 - "Addition of postdischarge oral secobarbital to a standard ED migraine treatment regimen decreased headache pain at 24 hours after discharge and improved the rate of headache resolution compared with placebo." 01/01/2011 - "The objective of the study was to determine whether the addition of postdischarge oral secobarbital to standard emergency department (ED) migraine headache therapy improves pain relief and headache resolution compared with placebo. "
2.	Migraine Disorders (Migraine) 01/01/2011 - "Postdischarge secobarbital after ED migraine treatment decreases pain and improves resolution." 01/01/2011 - "Patients with a clinical diagnosis of migraine underwent standard ED treatment and were discharged with 2 tablets of either secobarbital 100 mg or placebo. " 01/01/2011 - "Addition of postdischarge oral secobarbital to a standard ED migraine treatment regimen decreased headache pain at 24 hours after discharge and improved the rate of headache resolution compared with placebo." 01/01/2011 - "The objective of the study was to determine whether the addition of postdischarge oral secobarbital to standard emergency department (ED) migraine headache therapy improves pain relief and headache resolution compared with placebo. "
3.	Headache (Headaches) 01/01/2011 - "Ninety-four percent of the secobarbital group vs 50% of the placebo group had complete or partial headache resolution (P < .02). " 01/01/2011 - "Secobarbital subjects reported an average headache pain decrease of 25 mm (-13 to -38) compared with an average increase of 3 mm (-13 to 19) in the placebo group (P = .01). " 01/01/2011 - "Addition of postdischarge oral secobarbital to a standard ED migraine treatment regimen decreased headache pain at 24 hours after discharge and improved the rate of headache resolution compared with placebo." 01/01/2011 - "The objective of the study was to determine whether the addition of postdischarge oral secobarbital to standard emergency department (ED) migraine headache therapy improves pain relief and headache resolution compared with placebo. "
4.	Chronic Disease (Chronic Diseases) 02/01/1956 - "A study of hypnotic drugs in patients with chronic diseases; comparative efficacy of placebo; methyprylon (noludar) meprobmate (miltown, equanil) pentobarbial; phenobarbital; secobarbital."
5.	Vomiting 08/15/1986 - "The efficacy of secobarbital sodium plus chlorpromazine (SC) in the prevention of cisplatin induced emesis was compared to the combination of metoclopramide, diphenhydramine, and dexamethasone (MDD). "

Related Drugs and Biologics

1.	Phenobarbital (Luminal)
2.	Meprobamate (Miltown)
3.	methyprylon
4.	Chlorpromazine (Thorazine)
5.	Warfarin (Coumadin)
6.	Metoclopramide (Reglan)
7.	Diphenhydramine (Benadryl)
8.	Dexamethasone (Maxidex)
9.	Cisplatin (Platino)
10.	Pentobarbital (Nembutal)

Related Therapies and Procedures

1.	Anesthesia
2.	Intra-Arterial Injections
3.	Drug Therapy (Chemotherapy)
4.	Neurosurgical Procedures
5.	Sympathectomy (Sympathectomies)