HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Sea-Blue Histiocyte Syndrome (Sea Blue Histiocytosis)

A congenital disease caused by an inborn error involving APOLIPOPROTEINS E leading to abnormal LIPID METABOLISM and the accumulation of GLYCOSPHINGOLIPIDS, particularly SPHINGOMYELINS in the HISTIOCYTES. This disorder is characterized by SPLENOMEGALY and the sea-blue histiocytes in the spleen and bone marrow after May Grunwald staining.
Also Known As:
Sea Blue Histiocytosis; Histiocyte Syndrome, Sea Blue; Histiocyte Syndromes, Sea Blue; Sea-Blue Histiocyte Disease; Sea-Blue Histiocytosis; Disease, Sea-Blue Histiocyte; Diseases, Sea-Blue Histiocyte; Histiocyte Disease, Sea-Blue; Histiocyte Diseases, Sea-Blue; Histiocyte Syndrome, Sea-Blue; Histiocyte Syndromes, Sea-Blue; Histiocytoses, Sea Blue; Histiocytoses, Sea-Blue; Histiocytosis, Sea Blue; Sea Blue Histiocyte Disease; Sea Blue Histiocyte Syndrome; Sea Blue Histiocytoses; Sea-Blue Histiocyte Diseases; Sea-Blue Histiocyte Syndromes; Sea-Blue Histiocytoses; Syndrome, Sea-Blue Histiocyte; Syndromes, Sea-Blue Histiocyte; Histiocytosis, Sea-Blue
Networked: 23 relevant articles (0 outcomes, 2 trials/studies)

Disease Context: Research Results

Related Diseases

1. Niemann-Pick Diseases (Niemann Pick Disease)
2. Splenomegaly
3. Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)
4. Type B Niemann-Pick Disease
5. Type A Niemann-Pick Disease

Experts

1. Bhardwaj, Arshia: 1 article (09/2020)
2. D'Cruz, Sanjay: 1 article (09/2020)
3. Gaba, Saurabh: 1 article (09/2020)
4. Gupta, Monica: 1 article (09/2020)
5. Tahlan, Anita: 1 article (09/2020)
6. Hoff, David S: 1 article (05/2015)
7. Wu, Ting Ting: 1 article (05/2015)
8. Akar Özkan, Eylem: 1 article (04/2015)
9. Ayva, E Åžebnem: 1 article (04/2015)
10. Boyvat, Fatih: 1 article (04/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Sea-Blue Histiocyte Syndrome:
1. EmulsionsIBA
2. Immunoglobulin M (IgM)IBA
3. Immunoglobulin G (IgG)IBA
4. LipidsIBA
5. Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA
6. EnzymesIBA
7. CeroidIBA
8. Apolipoproteins E (ApoE)IBA
9. Triglycerides (Triacylglycerol)IBA
10. HDL CholesterolIBA

Therapies and Procedures

1. Total Parenteral Nutrition
2. Splenectomy
3. Parenteral Nutrition
4. Home Parenteral Nutrition