Scorpion Venoms (Scorpion Venom)

Venoms from animals of the order Scorpionida of the class Arachnida. They contain neuro- and hemotoxins, enzymes, and various other factors that may release acetylcholine and catecholamines from nerve endings. Of the several protein toxins that have been characterized, most are immunogenic.

Also Known As:

Networked: 137 relevant articles (4 outcomes, 13 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Jia, Qing: 8 articles (07/2015 - 04/2009)
2.	Laraba-Djebari, Fatima: 5 articles (11/2015 - 01/2012)
3.	Zhao, Jie: 5 articles (11/2015 - 02/2002)
4.	Cao, Zhijian: 4 articles (04/2014 - 07/2011)
5.	Li, Wenxin: 4 articles (04/2014 - 07/2011)
6.	Deshpande, Shripad B: 4 articles (06/2012 - 09/2006)
7.	Zhang, Yueying: 4 articles (07/2011 - 01/2010)
8.	Wang, Zhaopeng: 4 articles (07/2011 - 01/2010)
9.	Zhang, Weidong: 4 articles (07/2011 - 01/2010)
10.	Zhang, Wan-Qin: 3 articles (11/2015 - 02/2002)

Related Diseases

1.	Bites and Stings (Sting) 04/01/2006 - "Efficacy of species specific anti-scorpion venom serum (AScVS) against severe, serious scorpion stings (Mesobuthus tamulus concanesis Pocock)--an experience from rural hospital in western Maharashtra." 11/01/2003 - "Anti scorpion venom did not prevent the cardiovascular manifestations of severe scorpion sting. " 05/01/1996 - "Scorpion venoms: taking the sting out of lung disease." 08/01/2004 - "Skin testing with scorpion venom was performed on scorpion sting-naive patients allergic to IFA venom. "
2.	Infection 04/01/2013 - "Here, we screened and identified a new peptide, Ctry2459, from a scorpion venom peptide library that was proven to inhibit hepatitis C virus (HCV) infection via inactivating infectious viral particles. " 12/01/2007 - "As the first step toward studying molecular mechanism of scorpion venom gland immunity, we established an infection model which supports inducible antibacterial response of scorpion venom gland. " 12/01/2007 - "Our work thus provides the first evidence supporting the role of venom antibacterial peptides (ABPs) in controlling scorpion venom gland infection and lays a basis for characterizing related components involved in regulation of scorpion venom gland ABP gene expression." 04/01/2005 - "This review offers detailed and comprehensive information about IgY-technology, including: a) possibilities for hen keeping in accordance with the Three Rs principles; b) new insights into the IgY transfer mechanism from blood to yolk as a biological basis for the technology; c) the comparative characteristics of IgY Abs and IgG Abs; d) the high efficacy of the technique, in view of the extraordinary amount of IgY Ab produced by one hen in one year (between 20 g and 40 g IgY in total); e) comparisons between the efficacies of IgY Abs and IgG Abs (rabbit, sheep, mouse) in several immunological assays; f) immunisation protocols, as well as the most commonly used IgY-extraction procedures; g) new possibilities for application in human and veterinary medicine, including strategies for the treatment of Helicobacter pylori infection or fatal intestinal diseases in children, particularly in poor countries, for reducing the use of antibiotics, and, in Asia and South America, for producing Abs against snake, spider and scorpion venoms; and h) the use of IgY Abs in various fields of research, also taking into consideration recent developments in South America (particularly Argentina and Cuba) and in Asia."
3.	Anaphylaxis (Anaphylactic Shock) 09/01/2014 - "Hyaluronidase is a common component of scorpion venom and has been considered as "spreading factor" that promotes a fast penetration of the venom in the anaphylactic reaction. " 07/01/2005 - "Basic and translational research observations indicate that improved diagnosis and therapy might become possible on the basis of reported identification or characterization of allergens such as: lipid transfer proteins and birch pollen-related cross-reactive allergens in plant foods; proteins in scorpion venom that cross-react with proteins from imported fire ant; mosquito saliva proteins responsible for systemic anaphylaxis; and IgE binding to quinolones detectable with an in vitro immunoassay. "
4.	Acidosis 06/01/2000 - "We conclude that T1 fraction of Tityus serrulatus scorpion venom induces in anaesthetized rats an acute respiratory acidosis followed by metabolic acidosis." 07/01/2002 - "In both series of experiments, volume administration improved cardiac output but had no effect on oxygen delivery, arterial pH, HCO3-, lactate, and gastric mucosal pH. Metabolic acidosis and cardiovascular abnormalities seen after scorpion venom injection in dogs are closely related to gastrointestinal hypoperfusion. "
5.	Cardiovascular Abnormalities 07/01/2002 - "In both series of experiments, volume administration improved cardiac output but had no effect on oxygen delivery, arterial pH, HCO3-, lactate, and gastric mucosal pH. Metabolic acidosis and cardiovascular abnormalities seen after scorpion venom injection in dogs are closely related to gastrointestinal hypoperfusion. "

Related Drugs and Biologics

1.	Immunoglobulin E (IgE)
2.	Oxygen
3.	Immunoglobulin G (IgG)
4.	Allergens
5.	Lactic Acid
6.	Quinolones
7.	Proteins (Proteins, Gene)
8.	Anti-Bacterial Agents (Antibiotics)
9.	IgY
10.	Sodium Channels (Sodium Channel)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Resuscitation
3.	Injections
4.	Therapeutics
5.	Intravenous Injections