Sclerosis

08/01/1990 - "The patients had severe disease; there was a high degree of glomerular sclerosis; the median serum creatinine was 137 mumol/l, the diastolic blood pressure 101 mm Hg. Reported previously was a short-term improvement in renal function, blood pressure, and renal histology. "
06/01/2015 - "Systolic blood pressure, urinary protein excretion, serum creatinine and glomerular sclerosis in Wistar rats were significantly lower than that of 5/6Nx SHRs. "
07/01/2013 - "Kidneys glomerular sclerosis and high creatinine levels were observed in group fed mucuna flour. "
09/01/2012 - "The number of urinary podocytes in patients with segmental sclerosis was higher than in patients without (1.05 [IQR, 0.41-1.67] per mg creatinine versus 0.28 [IQR, 0.10-0.66] per mg creatinine; P<0.01). "
09/01/2012 - "Levels of urinary protein excretion in patients with segmental sclerosis (n=19) were higher than in patients without (n=22) (0.49 [interquartile range (IQR), 0.20-0.88] g/g creatinine versus 0.20 [IQR, 0.10-0.33] g/g creatinine; P<0.01). "

11/01/2003 - "Sclerosis therapy with polidocanol microfoam was judged beneficial in 46 (92%) of the 50 patients. "
01/01/2014 - "Direct puncture and sclerosis with polidocanol foam are an effective treatment for LFVM of the face and oral cavity."
09/01/2002 - "Sonographically guided percutaneous injection of 1% polidocanol for sclerosis of peripheral vascular lesions is simple, effective, and safe. "
12/01/2011 - "To report the efficacy of percutaneous puncture and sclerosis using polidocanol in the treatment of venous malformations (VMs) in pediatric patients. "
03/01/2011 - "The efficacy of sclerosis was reported in total occlusion of 46 sites (92.0%) in foam therapy and of 38 sites (76.0%) in Polidocanol liquid therapy after 90 days. "

11/01/1997 - "Ethanol sclerosis is a well-tolerated, safe, and effective adjunct to the management of VMs. "
05/01/2015 - "In the ethanol-injected group, disc height gradually decreased and bone sclerosis developed in the endplate. "
01/01/2014 - "Treatment was based on interventional radiology with an US-guided drainage and sclerosis by ethyl alcohol of the lesion. "
11/01/2013 - "To achieve sclerosis, we administered absolute ethanol through direct puncture. "
07/01/2010 - "Absolute alcohol was used as the sclerosis agent. "

09/26/1955 - "[Combined urea, protein, and plant therapy of ascites and edema in chronic circulatory failure complicated by sclerosis of the liver]."
09/01/2007 - "Compared with group II, CrPic treatment also lowered free fatty acid levels by 24% (P < .001), blood urea by 33% (P < .05), and creatinine level by 25% (P < .01), and reduced the severity of glomerular sclerosis (P < .0001). "
01/01/2014 - "Meanwhile, serum creatinine and urea levels as well as glomerular sclerosis and tubulointerstitial injury indexes were decreased at 4 and 8 weeks. "
09/01/1990 - "In 6 wk, young rats developed more pronounced glomerular sclerosis and more marked elevation in blood urea nitrogen. "
12/01/1985 - "Sclerosis with quinine-urea is indicated in this situation. "

10/01/2008 - "Supportive histopathologic findings consisting of either fascial sclerosis or increased fibroblast cellularity with sclerotic collagen bundles in the deep reticular dermis and/or subcutaneous septa may help to confirm this diagnosis."
06/01/2005 - "The histological study of two patients revealed a variable degree of collagen alteration (sclerosis and hyalinization). "
03/01/1988 - "Ultrastructural study demonstrated that the tubular sclerosis was due to collagen deposition by fibromyocytes in the peritubular sheath. "
10/01/2014 - "Sclerosing disorders of the skin consist of a heterogeneous spectrum of entities that share in common cutaneous sclerosis with excessive local accumulation of collagen and/or other extracellular matrix components in the dermis, subcutaneous tissue, and/or underlying soft tissues. "
09/01/2014 - "Mast cell staining bordering areas of sclerosis indicated a possible role in the synthesis of collagen. "

07/01/2008 - "Glomerular sclerosis of diverse etiologies is characterized by mesangial matrix accumulation, with transforming growth factor-beta (TGFbeta) an important pathogenic factor. "
06/01/2008 - "Moreover, transforming growth factor-beta (TGF-beta) is the main cytokine in the development of tissue sclerosis. "
01/01/2001 - "The growth factor TGF-beta has emerged as a key participant in the cascade of events which leads to kidney sclerosis. "
11/01/1999 - "Although the pathogenic relevance of transforming growth factor-beta (TGF-beta) to glomerular sclerosis has been established, the intracellular mechanisms by which TGF-beta induces extracellular matrix accumulation are not fully understood. "
08/01/1998 - "TGF-beta, but not PDGF, also changed the quality of the de novo synthesized FN, and thus has a different role in the development of sclerosis."

03/01/2001 - "Adriamycin plus CD4(+) depletion mice had significantly greater mesangial expansion, glomerular sclerosis, and interstitial expansion than the mice on adriamycin alone. "
06/01/1990 - "The study also suggested that LED produces less venous sclerosis than free doxorubicin, but this requires further clinical verification."
01/01/2015 - "QLXB could partly improve glomerular sclerosis in adriamycin-induced nephropathy, which was related to inhibition of CTGF, FN and α-SMA expression."
01/01/2015 - "To explore the eff ect of Qiluxiaobai (QLXB) decoction on rats with adriamycin (ADR)- induced focal segmental glomerular sclerosis (FSGS) nephropathy (ADN). "
01/01/2015 - "[Effect of Qiluxiaobai decoction on glomerular sclerosis in adriamycin-induced nephropathic rats]."

02/01/1991 - "This resulted in excellent palliation in patients with terminal disease and improvement in the clinical status of other patients so that additional therapies, such as sclerosis with tetracycline or surgical placement of a pericardial window, could be performed on an elective basis."
04/01/2008 - "There was no decrease in the drainage so we decided to perform pericardial sclerosis by intrapericardial tetracycline instillation. "
04/01/1999 - "This was successfully treated by an injection of tetracycline to induce sclerosis."
06/01/1995 - "Tetracycline sclerosis."
05/01/1993 - "Its safety profile and efficacy compare favorably with those of tetracycline and other agents used for pleural sclerosis."

12/01/2000 - "Glomerular and vascular sclerosis increase with aging, and angiotensin inhibitors ameliorate progression of this injury. "
02/01/2014 - "The obvious hypertension that develops in Mdk(+/+) mouse models of renal ablation compared with Mdk(-/-) mice eventually leads to progressive renal failure, such as glomerular sclerosis and tubulointerstitial damage associated with elevated plasma angiotensin (Ang) II levels. "
01/01/2012 - "Mdk(+/+) mice exhibited marked hypertension in renal ablation model compared with Mdk(-/-) mice, eventually leading to more progressive renal failure such as glomerular sclerosis and tubulointerstitial injuries in association with elevated plasma angiotensin (Ang) II levels. "
04/01/2010 - "Angiotensin receptor blocker protection against podocyte-induced sclerosis is podocyte angiotensin II type 1 receptor-independent."
12/01/1997 - "Preclinical pharmacological studies in a variety of animal models have demonstrated that irbesartan provides a dose-dependent, insurmountable blockade of angiotensin and reductions in blood pressure, urinary protein and glomerular sclerosis score."

01/01/1999 - "A partial remission of the skin sclerosis was instead obtained by the administration of D-penicillamine. "
01/01/1990 - "Its action is favorable in sclerosis and in deep infiltration foci, when traditional therapy, including cuprenil, are of poor efficacy. "
05/01/2008 - "Several uncontrolled studies in systemic sclerosis have shown that D-penicillamine may cause improvement in skin sclerosis, decrease the rate of new visceral organ involvement, and improve overall survival. "
06/01/1992 - "Treatment with penicillamine may ameliorate the sclerosis of the morphea but does not stop new lesions from appearing."
08/01/2004 - "Following the treatment with oral prednisolone and D-penicillamine, her skin sclerosis gradually improved. "

01/01/1999 - "Following 4 cycles of chemotherapy, he had complete remission and the skin sclerosis remarkably improved. "
02/01/2001 - "In patients with PMLBCL with sclerosis, combined modality treatment using the MACOP-B chemotherapy regimen and radiation therapy induces a good remission rate with the patients having a greater than 90% chance of surviving disease-free at 9 years. "
06/01/2011 - "Local (intrapericardial) chemotherapy has been reported to be useful for the treatment of neoplastic pericardial disease, but it has never been compared to systemic chemotherapy, a combination of the two and simple pericardial drainage or sclerosis. "
06/01/1994 - "Factors that predicted shorter remission duration in a multivariate analysis were nodular sclerosis histology, bulky disease, and receipt of less than 85% of planned chemotherapy. "
09/01/2012 - "EBV-positive HL was associated with age of ≥ 25 years, male gender, B symptoms, advanced stage, high-risk IPS, nonnodular sclerosis subtype, and treatment with chemotherapy only (P < 0.05). "

08/01/2014 - "Mandibular condyle erosion and sclerosis in pediatric patients treated with radiotherapy to the head and neck region."
02/01/2007 - "Clinicopathologic findings in mesial temporal sclerosis treated with gamma knife radiotherapy."
12/01/1997 - "We report a patient with clinical stage IIA nodular sclerosis HD, originally treated with radiotherapy alone, who relapsed 24 years after the initial diagnosis. "
12/01/1997 - "In patient with cervical sclerosis after radiotherapy; the use of LMA should be avoided."
01/01/1994 - "Surgery was required and gave better results than radiotherapy, which left sites of sclerosis. "

03/01/1999 - "Not only can these readily non-invasive imaging techniques be used to monitor and document the efficacy of treatments designed to remedy defective lymph transport and function, but in certain conditions (e.g., chylous reflux syndrome), they can be employed to obliterate incompetent lymphangiectatic/lymphangiomatous truncal elements through sclerosis using percutaneous computer-guided catheters."
10/01/2015 - "Pooled recurrence rates for extended catheter drainage, pericardial sclerosis and PBP were 12.1%, 10.8% and 10.3%, respectively. "
05/01/2015 - "Left spermatic vein retrograde sclerosis: comparison between sclerosant agent injection through a diagnostic catheter versus through an occluding balloon catheter."
06/01/2006 - "Group II consisted of 50 patients who underwent the 3-S saphenectomy technique (sclerosis injection at the sapheno-femoral junction with microfoam through a catheter, with saphenectomy and distal phlebectomies). "
06/01/2001 - "Thirty-six patients had subxiphoid pericardial window (SXPW) alone (Group A), 5 had pericardial catheter drainage (PCD) followed by a SXPW (Group B), 10 had PCD with sclerosis (Group C), 5 had PCD alone (Group D), 2 had PCD with pericardial-pleural window (Group E), and one had pericardial-peritoneal window (Group F). "

01/01/1995 - "The osteopetrotic (op) mutation in mice is characterized by general skeletal sclerosis; reduced numbers of osteoclasts, macrophages, and monocytes; and failure to be cured by bone marrow transplantation. "
09/01/2006 - "Prevention of mesangial sclerosis by bone marrow transplantation."
02/01/2006 - "Bone marrow transplantation can attenuate the progression of mesangial sclerosis."
12/01/2001 - "X-ray confirmed attenuation of the bone sclerosis; therefore, bone marrow transplantation (BMT) was not implemented. "
02/01/1989 - "Bone marrow transplantation, originally shown to reverse the skeletal sclerosis in some animal mutations, has been effective in curing osteopetrosis in some children. "

05/01/2000 - "The prevalence of glomeruli with adhesions and/or cellular crescents in primary IgAN was significantly greater than in post-transplant IgAN (P<0.05), but the proportion of glomeruli with segmental sclerosis was similar in both groups. "
07/01/2015 - "The percent glomerular sclerosis was most often examined, and failed to predict graft failure in 7 of 14 studies. "
11/01/2012 - "In the current study, we examined the role of the RCMV chemokine r129 in promoting cellular migration and in accelerating transplant vascular sclerosis (TVS) in our rat heart transplant model. "
01/01/2011 - "The purpose of this study was to analyze the clinical follow-up results (minimum, 2 years) in patients with nonunions of the scaphoid with minimal sclerosis treated with arthroscopically assisted percutaneous internal fixation augmented by injection of a bone graft substitute. "
07/01/2015 - "Cytomegalovirus accelerates transplant vascular sclerosis (TVS) and chronic rejection (CR) in solid organ transplants; however, the mechanisms involved are unclear. "