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Sciatica (Sciatic Neuralgia)

A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.
Also Known As:
Sciatic Neuralgia; Sciatica, Bilateral; Bilateral Sciatica; Bilateral Sciaticas; Neuralgias, Sciatic; Sciatic Neuralgias; Neuralgia, Sciatic
Networked: 1282 relevant articles (157 outcomes, 253 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pain (Aches)
2. Low Back Pain (Lumbago)
3. Intervertebral Disc Displacement (Herniated Disc)
4. Back Pain (Backache)
5. Radiculopathy (Radiculopathy, Cervical)

Experts

1. Koes, Bart W: 29 articles (01/2021 - 11/2004)
2. Peul, Wilco C: 25 articles (02/2022 - 11/2004)
3. Karppinen, Jaro: 16 articles (01/2020 - 01/2002)
4. Brand, Ronald: 14 articles (10/2017 - 02/2005)
5. McLachlan, Andrew J: 13 articles (01/2022 - 02/2012)
6. van Tulder, Maurits W: 10 articles (02/2022 - 01/2006)
7. Maher, Christopher G: 9 articles (01/2021 - 07/2013)
8. Mathieson, Stephanie: 8 articles (01/2022 - 07/2013)
9. Ostelo, Raymond W J G: 8 articles (01/2021 - 11/2004)
10. Arts, Mark P: 8 articles (05/2015 - 05/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Sciatica:
1. SteroidsIBA
2. Adrenal Cortex Hormones (Corticosteroids)IBA
3. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
4. Etanercept (Enbrel)FDA Link
5. Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
6. Analgesics (Analgesic Drugs)IBA
7. Chymopapain (Chymodiactin)FDA Link
8. Local AnestheticsIBA
9. Infliximab (Remicade)FDA Link
10. Meloxicam (Mobic)FDA LinkGeneric

Therapies and Procedures

1. Conservative Treatment
2. Injections
3. Therapeutics
4. Epidural Injections
5. Diskectomy (Discectomy)