Schistosomicides

10/01/1989 - "Due to the low efficacy of schistosomicides in the acute toxaemic phase of schistosomiasis, some authors have suggested that specific treatment for schistosomiasis should be delayed, in these patients, until the disease has entered it's chronic stage (Stuiver, 1984; Harries and Cook, 1987). "
09/01/2021 - "(Lauraceae), as an antischistosomal agent orally active in schistosomiasis animal model. "
10/01/2018 - "Therefore, it is clear that there is a substantial need to develop novel and effective antischistosomal agents in order to ensure the effective drug control of schistosomiasis in the future. "
06/28/2016 - "This comprehensive review shall attempt to briefly review the recent advances in the chemotherapy of schistosomiasis in the literature from 1990s to now, particularly focusing on the context of potential development of antischistosomal agents. "
01/31/2013 - "This comprehensive review shall attempt to briefly review the recent advances in the chemotherapy of schistosomiasis in the literature from 1990s to now, particularly focusing on the context of potential development of antischistosomal agents. "

09/01/2005 - "mansoni infected mice at 9 weeks of infection with ART did not reduce the pathological findings or the mortality rate compared to treatment with the current recommended schistosomicides, PZQ and OX."
05/01/2003 - "mansoni to schistosomicide drugs, demonstrated in primary infections, also persists when the host is already infected. "
09/01/1984 - "By decreasing human sources of snail infection, an effective schistosomicide may have the epidemiologic impact of reducing transmission; assessment prevalence rates can be relevant indices of transmission levels only if the biologic effect of the schistosomicide is dissociated from its epidemiologic impact in a control program in which selective mass chemotherapy plays a dominant role. "
04/01/1995 - "Oxamniquine is a potent schistosomicide used clinically in the treatment of infections due to Schistosoma mansoni. "
01/01/1981 - "Toxicological profile of praziquantel, a new drug against cestode and schistosome infections, as compared to some other schistosomicides."

11/01/1975 - "Evaluation of schistosomicides against experimentally established Schistosoma mansoni infections in mice and hamsters."
05/01/1989 - "In this paper we report a synergistic effect between schistosomicides and steroids in the treatment of the early stages of Schistosoma mansoni infection in the mouse. "
01/01/1981 - "2-Cyclo-hexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one (praziquantel, EMBAY 8440, Biltricide), a new schistosomicide, given to subjects with Schistosoma mansoni infections in a single oral dose of 40 mg/kg or 50 mg/kg in 2 divided doses resulted in probable cure rates at 6 months of 74% and 88.1%, respectively. "
01/01/2003 - "To evaluate the therapeutic efficacy of oxamniquine and praziquantel, the two most clinically important schistosomicide drugs, and to compare the accuracy of faecal examination with the accuracy of oogram in testing for Schistosoma mansoni infection. "

01/01/1981 - "Praziquantel appears to be an effective, well tolerated and easily administrable schistosomicide and thus a favourable contribution to the control of urinary schistosomiasis."

01/01/1974 - "[Experimental studies on prevention of muscular cramps caused by 2 F-type schistosomicides]."