Salivary Proteins and Peptides

08/06/2001 - "These results indicate that DTH response against saliva provides most or all of the protective effects of this vaccine and that salivary gland proteins or their cDNAs are viable vaccine targets against leishmaniasis."
07/01/2014 - "Over the past years, there has been cumulative evidence that immunity to specific sand fly salivary proteins confers a significant level of protection against leishmaniasis. "
06/01/2000 - "The results indicate that sand fly salivary proteins may be of relevance to the study the epidemiology of leishmaniasis."
07/01/2012 - "As a consequence, identifying antigenic salivary proteins of different leishmaniasis vectors has currently become a major task in the field of anti-Leishmania vaccine development. "
01/01/2012 - "Herein, we review the immunity to sand fly salivary proteins in the context of its vector-parasite-host combinations and their vaccine potential, as well as some recent advances to shed light on the mechanism of how an immune response to sand fly saliva protects against leishmaniasis."

02/01/2007 - "These results support further studies on the association of salivary proteins with posttransplant complications including infections and GVHD."
01/01/2015 - "Multiple salivary proteins/factors have been identified/characterized that enhance pathogen infection. "
01/01/2013 - "The establishment of an experimental model that partially reproduces natural infection in dogs is very important to test vaccine candidates, mainly regarding those that use salivary proteins from the vector and new therapeutical approaches. "
01/01/2013 - "In addition, sand fly salivary proteins affect host immunity and have the potential to be a vaccine against Leishmania infection. "
01/01/2012 - "Mosquito salivary proteins (MSPs) modulate the host immune response, leading to enhancement of arboviral infections. "

01/01/2014 - "Repeatedly, studies have demonstrated the immunogenicity and protective efficacy of a number of sand fly salivary proteins against cutaneous and visceral leishmaniasis. "
05/01/2009 - "Sand fly salivary proteins induce strong cellular immunity in a natural reservoir of visceral leishmaniasis with adverse consequences for Leishmania."
01/01/2006 - "Yet very little is known about the molecular characteristics of salivary proteins from different sandflies, particularly from vectors transmitting visceral leishmaniasis, the fatal form of the disease. "
01/01/2012 - "tobbi transmits a cutaneous form of leishmaniasis, its salivary proteins are most similar to other Larroussius subgenus species transmitting visceral leishmaniasis. "

01/16/2006 - "Delayed-type hypersensitivity (DTH) response to arthropod vector salivary proteins is associated with protection against pathogen transmission. "
03/01/2007 - "The potential role of the identified salivary proteins in the transmission of pathogens and the induction of allergies is discussed."
03/01/2007 - "Salivary proteins of hematophagous Culicoides spp. are thought to play an important role in pathogen transmission and skin hypersensitivity. "
04/01/2006 - "Mosquito salivary proteins cause allergic reactions in humans. "
09/01/2001 - "The Triatoma infestans salivary gland proteins (TSGP) can induce local and systemic hypersensitivity reactions in humans. "

06/03/2008 - "Sand fly salivary proteins have been associated with protection against cutaneous leishmaniasis. "
01/01/2013 - "This analysis is the first description of salivary proteins from a sand fly of the subgenus Helcocyrtomyia and from vector of cutaneous leishmaniasis in the New World. "