Saccharin

12/01/2000 - "Nasal endoscopy, plain radiography of the paranasal sinuses, olfactometry, anterior rhinomanometry, and a saccharin-clearance test were carried out on days 1 and 7. Patients recorded rating scales of general discomfort, nasal airway obstruction, agreeableness of the irrigation, duration of improved nasal resistance after each irrigation, and the amount of additional nasal spray in a diary. "
03/01/1995 - "Saccharin transit time was not helpful in assessment of degree of nasal obstruction. "
01/01/1997 - "Nasal obstruction was estimated by subjective scoring and mucociliary transport was determined by the saccharin method. "
12/01/1996 - "In only one patient was the saccharin clearance prolonged beyond 20 min, and only one patient developed nasal obstruction postburn. "
09/01/1986 - "The influence of nasal obstruction on mucociliary transport is tested by the saccharin test (Andersen). "

08/01/1994 - "An absolute amount of a LiCl US was administered to 24 young-adult and 24 old-age rats during taste-aversion conditioning to determine whether the superior performance of old-age rats, when a 1% body-weight injection of a LiCl US is administered 3 hr. after a saccharin CS, is due to age-related differences in US intensity or the efficacy of LiCl. "
01/01/1999 - "In the present study we observed that lipopolysaccharide (LPS) administration provoked a characteristic reduction in body weight gain, food consumption, saccharin (but not water) consumption and nocturnal locomotor activity. "
09/01/2015 - "It was found that both chronic swim stress and repeated central LPS infusion induced depressive-like behaviors, including decreased body weight, reduced saccharin preference, and increased immobility time or shortened latency of immobility in the tail suspension test. "
01/01/2015 - "To condition rats to disfavor a sweet taste, consumption of a 0.1% saccharin solution in place of drinking water was paired with 0.15M LiCl (2% body weight, i.p.) to induce visceral discomfort. "
05/15/2014 - "Repeated exposure to IMO protected from the negative consequences of an acute IMO on activity in an open-field, saccharin intake and body weight gain. "

11/08/1985 - "In two-generation studies involving rats, however, there was evidence that the incidence of bladder tumors was significantly greater in saccharin-treated males of the second generation than in controls; the development of bladder tumors in rats seems to be a species- and organ-specific phenomenon for which there is currently no explanation. "
04/01/1985 - "Analysis of these studies leads to the conclusion that saccharin is not related to human bladder cancer."
07/01/1984 - "Based on the results of that and other rodent studies indicating an increased risk of bladder cancer associated with saccharin, the Commissioner of the Food and Drug Administration announced the agency's intention to propose a ban on saccharin. "
04/01/1982 - "Calculation of potential bias in the odds ratio illustrated by a study of saccharin use and bladder cancer."
07/01/1979 - "The review of various saccharin studies suggests that bladder tumors resulted following in utero exposure. "

04/01/2006 - "Twenty year follow-up of ciliary mobility after bilateral inferior turbinectomy for allergic rhinitis using saccharin."
08/01/2004 - "Measurements of the nasal airway included anterior rhinoscopy (AnR), peak inspiratory nasal flow, acoustic rhinometry, anterior rhinomanometry (ARM), and the saccharin test with rhinitis questionnaire scores providing a symptomatic measurement. "
03/01/1992 - "Fifty-six consecutive patients with nonallergic rhinitis were evaluated with nasal cytology and saccharin challenge. "
01/18/1988 - "[Evaluation of saccharin transport time in allergic rhinitis]."
02/01/2009 - "MAIT is more effective than RAIT at relieving nasal symptoms and decreasing total nasal resistance and saccharin transit time 1 to 3 years postoperatively in patients with persistent allergic rhinitis and who have substantial nasal obstruction."

08/01/2005 - "Induction of systemic protection against rust infection in broad bean by saccharin: effects on plant growth and development."
05/01/2013 - "The aim of the present prospective case-control study was to study, using saccharin and anterior rhinomanometry tests, whether CCHF infections caused any change in nasal physiology. "
10/23/2012 - "However, plants from parents treated with both ASM or saccharin exhibited significantly enhanced resistance to infection by Rhynchosporium commune, despite not being treated with elicitor themselves. "
08/01/2005 - "Foliar application of saccharin did not induce systemic protection to rust infection until 14 d after application and was less effective than saccharin applied as a soil drench. "
08/01/2005 - "Plants were then challenge inoculated with the rust 1, 6, 10 and 14 d following saccharin treatment, after which they were harvested, assessed for the intensity of rust infection and plant growth measurements conducted. "