Cys Transfer RNA

A transfer RNA which is specific for carrying cysteine to sites on the ribosomes in preparation for protein synthesis.

Also Known As:

RNA, Transfer, Cys; tRNA(Cys); Cysteine Specific tRNA; RNA, Cys Transfer; tRNA, Cysteine-Specific; Cysteine-Specific tRNA; Transfer RNA, Cys; tRNACys

Networked: 18 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 11752
  - RNA: 69704
    - Transfer RNA: 2235
      - Amino Acid-Specific Transfer RNA: 1
        Cys Transfer RNA: 18

Experts

1.	Dong, Guanping: 2 articles (01/2020 - 01/2020)
2.	Fu, JunFen: 2 articles (01/2020 - 01/2020)
3.	Huang, Ke: 2 articles (01/2020 - 01/2020)
4.	Ji, Yanchun: 2 articles (01/2020 - 01/2020)
5.	Mao, Xiaoting: 2 articles (01/2020 - 01/2020)
6.	Meng, Feilong: 2 articles (01/2020 - 01/2020)
7.	Wang, Jinling: 2 articles (01/2020 - 01/2020)
8.	Zhao, Ningning: 2 articles (01/2020 - 01/2020)
9.	Ding, Yu: 1 article (01/2020)
10.	Finsterer, Josef: 1 article (01/2020)

Related Diseases

1.	Mitochondrial Diseases (Mitochondrial Disease) 04/01/2015 - "Although there are increasing reports showed a positive link between mitochondrial tRNACys G5821A mutation and mitochondrial diseases. " 02/01/2014 - "This mutation may abol-ish the predicted G6-C67 pairing and consequently affect the structure and stability of mitochondrial tRNACys, thereby leading to mitochondrial dysfunction. " 01/01/2020 - "Sequence analysis of the mitochondrial genomes from matrilineal relatives suggested the presence of three evolutionarily conserved mutations: tRNACys T5802C, tRNALys A8343G and tRNAThr G15930A, which may result the failure in tRNAs metabolism and lead to mitochondrial dysfunction that was responsible for deafness. "
2.	Obesity 01/01/2020 - "Reply to comments on: "Obesity associated with a novel mitochondrial tRNACys 5802A>G mutation in a Chinese family"." 01/01/2020 - "Obesity associated with a novel mitochondrial tRNACys 5802A>G mutation in a Chinese family." 01/01/2020 - "Letter to the Editor: Comments on "Obesity associated with a novel mitochondrial tRNACys m.5802A>G mutation in a Chinese family"." 01/01/2020 - "In a recent article Wang et al. reported about a 9-year-old Chinese male with obesity, insulin resistance, acanthosis nigricans, hyperuricemia, and non-alcoholic fatty liver disease (NALFD) being attributed to the variant m.5802A>G in tRNA(Cys) (Bioscience Reports (2020) 40(1), BSR20192153). "
3.	Deafness (Deaf Mutism) 01/01/2022 - "In this report, we investigated the molecular mechanism underlying a deafness-associated m.5783C > T mutation that affects the canonical C50-G63 base-pairing of TΨC stem of tRNACys and immediately adjacent to 5' end of light-strand origin of mitochondrial DNA (mtDNA) replication (OriL). " 05/15/2008 - "Mitochondrial ND5 T12338C, tRNA(Cys) T5802C, and tRNA(Thr) G15927A variants may have a modifying role in the phenotypic manifestation of deafness-associated 12S rRNA A1555G mutation in three Han Chinese pedigrees." 01/01/2020 - "Sequence analysis of the mitochondrial genomes from matrilineal relatives suggested the presence of three evolutionarily conserved mutations: tRNACys T5802C, tRNALys A8343G and tRNAThr G15930A, which may result the failure in tRNAs metabolism and lead to mitochondrial dysfunction that was responsible for deafness. "
4.	Neoplasms (Cancer) 01/01/2022 - "The tRNA-Cys-GCA derived tRFdb-3003a and tRFdb-3003b might act as key player in tumor progressions of gliomas; tRFdb-3003a/b might directly bind to VAV2 and regulate VAV2 expressions in gliomas." 01/01/2022 - "The tRNA-Cys-GCA Derived tsRNAs Suppress Tumor Progression of Gliomas via Regulating VAV2." 03/25/1983 - "Some novel mutations found in the tRNA genes of tumor mitochondria were as follows: nucleotides deletions in the aminoacyl-acceptor stem of the tRNATyr gene or in the anticodon stem of the tRNATrp gene and insertions in the "YpsiC" loop of the tRNACys gene. "
5.	Mitochondrial encephalopathy 05/01/1997 - "Mitochondrial tRNA(Cys) gene mutation (A5814G): a second family with mitochondrial encephalopathy." 01/01/1996 - "Identification of a mutation in the mitochondrial tRNA(Cys) gene associated with mitochondrial encephalopathy."

Related Drugs and Biologics

1.	Transfer RNA (tRNA)
2.	Thr Transfer RNA
3.	Met Transfer RNA
4.	Transketolase
5.	Thiamine (Aneurin)
6.	Tyr Transfer RNA
7.	Trp Transfer RNA (tRNA(Trp))
8.	Lys Transfer RNA
9.	RNA (Ribonucleic Acid)
10.	Proteins (Proteins, Gene)