Asp Transfer RNA

A transfer RNA which is specific for carrying aspartic acid to sites on the ribosomes in preparation for protein synthesis.

Also Known As:

RNA, Transfer, Asp; tRNA(Asp); Acid-Specific tRNA, Aspartic; Aspartic Acid Specific tRNA; RNA, Asp Transfer; tRNA, Aspartic Acid-Specific; Aspartic Acid-Specific tRNA; Transfer RNA, Asp; tRNAAsp

Networked: 19 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 11752
  - RNA: 69704
    - Transfer RNA: 2235
      - Amino Acid-Specific Transfer RNA: 1
        Asp Transfer RNA: 19

Experts

1.	Guan, Min-Xin: 2 articles (11/2020 - 12/2016)
2.	Wang, Meng: 2 articles (11/2020 - 12/2016)
3.	Zheng, Jing: 2 articles (12/2016 - 12/2013)
4.	Fu, Haiying: 1 article (03/2022)
5.	Sun, Jinming: 1 article (03/2022)
6.	Xu, Xiaoyan: 1 article (03/2022)
7.	He, Qiufen: 1 article (11/2020)
8.	Jia, Zidong: 1 article (11/2020)
9.	Meng, Feilong: 1 article (11/2020)
10.	Wang, Haibo: 1 article (11/2020)

Related Diseases

1.	Starvation 02/19/2010 - "Interestingly, glucose starvation drives enolase to accumulate within the nucleus, which in turn leads to the formation of additional enolase-E.histolytica DNMT2 homolog (Ehmeth) complex, and to a significant reduction of the tRNA(Asp) methylation in the parasite. " 10/01/1977 - "Previously, we reported that starvation of Rel Escherichia coli for methionine, but not leucine or histidine, results in chromatographically unique species of aspartyl-specific transfer ribonucleic acid (tRNAAsp) lacking the modified nucleoside Q. "
2.	Thyroid Neoplasms (Thyroid Cancer) 12/01/2015 - "To address this problem, in this study, we reassessed seven reported mt-tRNA variants: tRNAAsp G7521A, tRNAArg T10411C and T10463C, tRNALeu(CUN) A12308G, tRNAIle G4292C and C4312T, and tRNAAla T5655C, in clinical manifestations of thyroid cancer. "
3.	Hepatocellular Carcinoma (Hepatoma) 09/10/1981 - "The nucleotide sequences of the major tRNAAsp from rat liver and a minor tRNAAsp present specifically in rat ascites hepatoma were determined by combined use of several postlabeling procedures. " 06/11/1992 - "The nucleotide sequences of major cytoplasmic tRNA(Asp) from rat liver and rat ascites hepatoma comprise a U32 and C33 next to the anticodon as was confirmed by different procedures. " 02/01/1977 - "tRNAAsp from rabbit liver, rat liver and rat ascites hepatoma was readily isolated by concanavalin A-Sepharose (Con A-Sepharose) affinity column chromatography. " 09/10/1981 - "The nucleotide sequence of rat ascites hepatoma TRNAAsp was found to be the same as that of rat liver tRNAAsp, except that mannose-attached queuosine (manQ) present in the wobbling position of rat liver tRNAAsp was replaced by normal guanosine in rat ascites hepatoma tRNAAsp. " 09/01/1978 - "In the rat ascites hepatoma AH7974, the guanine was mostly incorporated into minor isoaccepting species of tRNAAsp that contained the guanine residue instead of Q base in the first position of the anticodon. "
4.	Ascites 09/10/1981 - "The nucleotide sequences of the major tRNAAsp from rat liver and a minor tRNAAsp present specifically in rat ascites hepatoma were determined by combined use of several postlabeling procedures. " 06/11/1992 - "The nucleotide sequences of major cytoplasmic tRNA(Asp) from rat liver and rat ascites hepatoma comprise a U32 and C33 next to the anticodon as was confirmed by different procedures. " 02/01/1977 - "tRNAAsp from rabbit liver, rat liver and rat ascites hepatoma was readily isolated by concanavalin A-Sepharose (Con A-Sepharose) affinity column chromatography. " 09/10/1981 - "The nucleotide sequence of rat ascites hepatoma TRNAAsp was found to be the same as that of rat liver tRNAAsp, except that mannose-attached queuosine (manQ) present in the wobbling position of rat liver tRNAAsp was replaced by normal guanosine in rat ascites hepatoma tRNAAsp. " 09/01/1978 - "In the rat ascites hepatoma AH7974, the guanine was mostly incorporated into minor isoaccepting species of tRNAAsp that contained the guanine residue instead of Q base in the first position of the anticodon. "
5.	Deafness (Deaf Mutism) 12/15/2016 - "In this report, we investigated the pathogenic mechanism underlying the deafness-associated mitochondrial(mt) tRNAAsp 7551A > G mutation. " 12/15/2016 - "A deafness-associated tRNAAsp mutation alters the m1G37 modification, aminoacylation and stability of tRNAAsp and mitochondrial function." 11/04/2020 - "In this report, we investigated the molecular mechanism underlying a deafness-associated m.7516delA mutation affecting the 5' end processing sites of mitochondrial tRNAAsp and tRNASer(UCN). " 12/01/2013 - "We reported here the clinical and genetic evaluations as well as mutational analysis of mitochondrial DNA(mtDNA) in a Chinese family with maternally transmitted non-syndromic hearing loss and investigated the influence of the mitochondrial tRNA(Asp) A7551G mutation to the phenotypic manifestation of the deafness. "

Related Drugs and Biologics

1.	Phosphopyruvate Hydratase (Enolase)
2.	Glucose (Dextrose)
3.	Leu Transfer RNA
4.	Ile Transfer RNA
5.	Arg Transfer RNA
6.	Ala Transfer RNA
7.	Transfer RNA (tRNA)
8.	Anticodon
9.	Tyr Transfer RNA
10.	His Transfer RNA