Ribosomal RNA

The most abundant form of RNA. Together with proteins, it forms the ribosomes, playing a structural role and also a role in ribosomal binding of mRNA and tRNAs. Individual chains are conventionally designated by their sedimentation coefficients. In eukaryotes, four large chains exist, synthesized in the nucleolus and constituting about 50% of the ribosome. (Dorland, 28th ed)

Also Known As:

Networked: 321 relevant articles (6 outcomes, 23 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Yoshioka, Norie: 4 articles (05/2014 - 09/2006)
2.	Kishimoto, Koji: 4 articles (05/2014 - 09/2006)
3.	Crawford, Nigel P S: 3 articles (12/2014 - 11/2007)
4.	Ibaragi, Soichiro: 3 articles (05/2014 - 11/2012)
5.	Hannan, Ross D: 3 articles (11/2013 - 02/2011)
6.	Hu, Guo-fu: 3 articles (11/2012 - 09/2006)
7.	Esser, Karyn A: 2 articles (08/2015 - 12/2005)
8.	Tsuneoka, Makoto: 2 articles (01/2015 - 05/2010)
9.	Tanaka, Yuji: 2 articles (01/2015 - 05/2010)
10.	Okamoto, Kengo: 2 articles (01/2015 - 05/2010)

Related Diseases

1.	Infection 03/01/2011 - "Time to clearance of Chlamydia trachomatis ribosomal RNA in women treated for chlamydial infection." 01/01/2013 - "In this study, we investigated (99m)Tc labeled MORF oligomers targeting fungal ribosomal RNA (rRNA) for the imaging detection of fungal infections. " 03/01/2010 - "The objective of the present study was to determine whether reverse transcription-quantitative polymerase chain reaction (RT-qPCR) using universal primers can be used to detect the more abundant bacterial ribosomal RNA (rRNA) as an indicator of periprosthetic infection. " 11/01/1991 - "To confirm and study such infections, we developed a hybridization screening system directed toward chlamydial ribosomal RNA (rRNA). " 05/01/2015 - "Although delay in ribosomal RNA decline after resolution of the infection might have led to an underestimation of spontaneous clearance, in high-risk STI clinic patients, testing the pharynx for chlamydia should be considered."
2.	Malaria 07/01/2010 - "Malaria parasite detection was made by the gold standard (microscopy) and also nested-PCR assay, using 18S small sub-unit ribosomal RNA (ssrRNA) gene. " 04/01/1996 - "To study the mechanisms involved in this striking difference in the infectivity of these closely related species of malaria parasites, we have developed a quantitative PCR targeted to parasite-specific ribosomal RNA. " 02/08/2002 - "The target DNA sequence of the 18S small sub-unit ribosomal RNA (ssrRNA) gene was amplified by Polymerase Chain Reaction (PCR) and used for the diagnosis of malaria in south-eastern Iran. " 04/30/1999 - "The start site of the A-type ribosomal RNA transcription units of the rodent malaria parasite, Plasmodium berghei, has been identified. " 01/01/1990 - "The number and expression of some of the large ribosomal RNA (rRNA) gene classes present in the human malaria parasite Plasmodium falciparum was determined. "
3.	Sepsis (Septicemia) 01/01/2010 - "Efficacy of bacterial ribosomal RNA-targeted reverse transcription-quantitative PCR for detecting neonatal sepsis: a case control study." 01/01/2010 - "The main purpose of this study was to identify etiological agents in clinically diagnosed neonatal sepsis using bacterial ribosomal RNA-targeted reverse transcription-quantitative PCR (BrRNA-RT-qPCR) and to conduct comparisons with the results of conventional blood culture. "
4.	Cicatrix (Scar) 07/01/2012 - "For example, recent studies with ribosomal RNA-based nucleic acid amplification tests (NAATs) have demonstrated improved sensitivities compared to DNA-based NAATs; and the progression of scarring has now been characterized with confocal microscopy. "
5.	Hematologic Neoplasms (Hematological Malignancy) 08/01/2004 - "Improved laboratory diagnosis of bacterial and fungal infections in patients with hematological malignancies using PCR and ribosomal RNA sequence analysis."

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)
2.	Azithromycin (Zithromax)
3.	Anti-Bacterial Agents (Antibiotics)
4.	Methyltransferases
5.	Paraffin
6.	RNA (Ribonucleic Acid)
7.	Proteins (Proteins, Gene)
8.	Nucleic Acid Probes
9.	Electron Transport Complex IV (Cytochrome c Oxidase)
10.	Gentamicins (Gentamicin)

Related Therapies and Procedures

1.	Heterologous Transplantation (Xenotransplantation)
2.	Esophagectomy
3.	Stents
4.	Continuous Ambulatory Peritoneal Dialysis (CAPD)
5.	Castration