Rinderpest (Cattle Plague)

A viral disease of cloven-hoofed animals caused by MORBILLIVIRUS. It may be acute, subacute, or chronic with the major lesions characterized by inflammation and ulceration of the entire digestive tract.

Also Known As:

Networked: 150 relevant articles (1 outcomes, 7 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Infection
2.	Rabies (Hydrophobia)
3.	Acquired Immunodeficiency Syndrome (AIDS)
4.	Peste-des-Petits-Ruminants
5.	Measles

Experts

1.	Shaila, M S: 5 articles (02/2004 - 01/2001)
2.	Barrett, T: 4 articles (01/2003 - 03/2000)
3.	Barrett, Thomas: 3 articles (03/2012 - 02/2005)
4.	Baron, M D: 3 articles (01/2003 - 03/2000)
5.	Banyard, Ashley C: 2 articles (05/2014 - 03/2012)
6.	Buczkowski, Hubert: 2 articles (05/2014 - 03/2012)
7.	Parida, Satya: 2 articles (05/2014 - 03/2012)
8.	Pastoret, P-P: 2 articles (12/2012 - 01/2005)
9.	Bailey, Dalan: 2 articles (03/2012 - 06/2005)
10.	Lubroth, J: 2 articles (01/2010 - 01/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Rinderpest:

1.	Synthetic Vaccines (Recombinant Vaccines)IBA 01/01/1995 - "Vaccinia virus recombinant vaccines for rinderpest." 01/01/1993 - "This laboratory has recently developed several effective vaccinia virus recombinant vaccines for rinderpest. " 02/01/1997 - "Cattle vaccinated with the recombinant vaccines after prior infection with the parental capripox virus showed more marked clinical signs of rinderpest after challenge with virulent rinderpest, but 9 out of 10 recovered, compared with 80% mortality in the unvaccinated controls." 11/01/1999 - "Live recombinant vaccines against rabies and rinderpest have proven to be highly effective for controlling these infections in the field, and those for AIDS are under clinical trial. "
2.	AntibodiesIBA 12/01/1999 - "A study was undertaken regarding the prevalence of bovine viral diarrhoea virus (BVDV) antibodies in bovine sera which tested negative for rinderpest and peste des petits ruminants virus antibodies. " 01/01/1969 - "[Rinderpest vaccination trial of calves passively immune due to colostrum antibodies with an inactivated adjuvated vaccine prepared in cell cultures]." 01/01/2009 - "A rinderpest competition ELISA, for the estimation of antibodies in serum samples, is used to demonstrate the methods. " 10/01/2008 - "It was also suggested that antibodies to PPR virus could prevent an immune response to the rinderpest vaccine. " 10/01/2007 - "From a total of 606 sera; 65 tissue samples and 75 swabs received, no rinderpest virus or specific gene products or antibodies against rinderpest were detected. "
3.	AntigensIBA 08/01/1991 - "The percentage antibody-positivity level (taken as an approximation of past experience with rinderpest antigen and the corresponding prevalence ratio estimates of relative risk) for each variable are discussed within the context of the known characteristics of immunity to rinderpest in endemic areas and the husbandry practices of the cattle owners in the study area. " 10/01/2001 - "The stability of the specific viral antigen was monitored for 4 days, and rinderpest and PPR antigens were still detected, depending on the type of specimen. " 12/01/2000 - "A 45% inhibition of the binding of the MAb to the antigen was used as the cut-off point for deciding the rinderpest status of the test samples. " 06/01/2000 - "These were tested in the field using a prototype of the pen-side test and 13 (12.15%) of the samples were found to be positive for the presence of rinderpest antigen. " 06/01/2000 - "A simple chromatographic strip-test based on Clearview technology, is under development as a pen-side test for the detection of rinderpest antigen in eye swabs taken from cattle in the field. "
4.	InterferonsIBA 01/01/1980 - "Studies on viral interference induced by rinderpest virus: interference and interferon induction by tissue culture rinderpest vaccine (TCRV) virus in vitro." 03/01/1982 - "Studies on viral interference induced by rinderpest virus: 4. Induction of circulating interferon and antibodies in buffaloes following inoculation with tissue culture rinderpest vaccine (TCRV) virus."
5.	Complement System Proteins (Complement)IBA 01/01/1959 - "The complement fixation test and its application to the diagnosis of rinderpest." 08/01/1978 - "Studies on the preparation of rinderpest antigen for use in conglutinating complement absorption test." 09/01/1993 - "Both institutes confirmed the presence of rinderpest using complement fixation, agar gel diffusion and immunoassays. " 06/01/1993 - "Several tests already exist, such as complement deoxyribonucleic acid (cDNA)-specific probes and polymerase chain reaction (PCR) for rinderpest and PPR, DNA probes and PCR for CBPP, capture enzyme-linked immunosorbent assay, the agglutination test and the immunobinding peroxidase test for CCPP, etc. With specific reference to these examples, the various problems faced by the OIE and CAMDA are reviewed."
6.	Nucleocapsid ProteinsIBA 01/05/2001 - "We extended our study to the bovine system both to analyze the immunogenicity of these recombinant proteins in the natural hosts and to show that PBMC from cattle vaccinated with Rinderpest vaccine proliferate in vitro, in response to restimulation with soluble nucleocapsid proteins. " 01/05/2001 - "Identification of a cytotoxic T-cell epitope on the recombinant nucleocapsid proteins of Rinderpest and Peste des petits ruminants viruses presented as assembled nucleocapsids."
7.	Recombinant ProteinsIBA 01/05/2001 - "We extended our study to the bovine system both to analyze the immunogenicity of these recombinant proteins in the natural hosts and to show that PBMC from cattle vaccinated with Rinderpest vaccine proliferate in vitro, in response to restimulation with soluble nucleocapsid proteins. "
8.	VaccinesIBA 02/01/2014 - "Pathways leading to rinderpest re-introduction were: deliberate or accidental use of virus in laboratories, deliberate or accidental use of vaccines, host exposure to an environmental source of virus, and use of virus for anti-animal biological warfare. " 03/02/2012 - "A novel approach to generating morbillivirus vaccines: negatively marking the rinderpest vaccine." 01/01/2010 - "Both diseases can be controlled by vaccination, although the post-vaccination immunity afforded by the rinderpest vaccine is markedly different from that induced by FMD vaccines. " 02/01/2005 - "The success of the Global Rinderpest Eradication Program is an illustration of the power of vaccines to alter people's lives economically and socially when used in an internationally coordinated way. " 01/01/2005 - "The only animal virus disease sharing these characteristics is rinderpest, for which there are several efficacious vaccines. "
9.	Monoclonal AntibodiesIBA 10/01/2004 - "The reactivity pattern of the monoclonal antibodies in indirect ELISA indicated a close antigenic relationship within three Indian PPR (lineage 4) virus isolates and also within two rinderpest vaccine strains. " 12/01/1998 - "It reacted with rinderpest and 'N' protein specific monoclonal antibodies in Enzyme Linked Immunosorbent Assay (ELISA). " 10/01/1990 - "Monoclonal antibodies (MAbs) were obtained using a purified preparation of the RBOK strain of a rinderpest vaccine virus. " 07/01/1986 - "The antigenic relationship between measles, canine distemper and rinderpest viruses studied with monoclonal antibodies." 02/15/1991 - "Monoclonal antibodies (MAb) raised against the RBOK vaccine strain of rinderpest virus were characterized by radio-immunoprecipitation (RIPA) and in the indirect ELISA using measles (MV), distemper (CDV), rinderpest (RPV) and peste des petits ruminants viruses (PPRV). "
10.	Proteins (Proteins, Gene)IBA 06/01/2005 - "However, at the protein level five of the six structural proteins and the V protein showed a greater similarity to the dolphin morbillivirus (DMV) while only the C and L proteins showed a high relationship to rinderpest." 03/01/2000 - "We have constructed recombinant rinderpest viruses in which the expression of these proteins has been suppressed, individually and together, and studied the replication of these viruses in tissue culture. " 03/01/2000 - "Rinderpest viruses lacking the C and V proteins show specific defects in growth and transcription of viral RNAs." 07/01/1987 - "Comparison of proteins induced in cells infected with rinderpest and peste des petits ruminants viruses." 12/01/1981 - "Analysis of structural proteins of measles, canine distemper, and rinderpest viruses."

Therapies and Procedures

1.	Injections 11/01/1985 - "Rinderpest neutralising antibody concentrations in sera following injections of rinderpest antigen."