Rickets (Rachitis)

08/04/2011 - "Vitamin D supplementation for the prevention of rickets is one of the oldest and most effective prophylactic measures in medicine, having virtually eradicated rickets in North America. "
07/01/2004 - "Her rickets improved dramatically with vitamin D treatment. "
01/01/2014 - "Firstly, discovery that vitamin D is the cure for rickets, brought us supplementation programs and rapid irradiation of this devastating disease. "
07/01/2011 - "Successful therapy of vitamin D-dependant rickets in a kitten."
05/01/1992 - "To determine whether amounts of vitamin D lower than recommended doses are effective in preventing rickets, 256 term infants from two northern and two southern cities in China were studied in a randomized trial of vitamin D supplementation (100, 200, or 400 IU/day) during the first 6 months of life. "

09/01/2007 - "Despite the lack of a statistically significant association between radiographic improvement and compliance with nutritional advice, in mild calcium-deficiency active rickets, nutritional advice may be a cost-effective treatment and possibly a valuable long-term solution to the problem."
11/01/2004 - "Mean fractional calcium absorption was significantly greater after (81 +/- 10%) than before (61 +/- 20%) calcium supplementation for the treatment of rickets (P = 0.035). "
03/01/2008 - "Apparent efficacy of food-based calcium supplementation in preventing rickets in Bangladesh."
10/01/2012 - "Studies from some tropical countries have postulated low dietary intake of calcium as the cause of nutritional rickets. "
11/01/2010 - "Studies of Nigerian children with rickets demonstrated they have high fractional calcium absorption. "

01/01/1980 - "It is concluded that high intermittent oral doses of vitamin D3 give an effective protection against rickets but at the cost of several times higher 25-OH-D concentration in serum and at the risk of hypervitaminosis D in some healthy infants."
02/01/2010 - "An IM injection of a mega dose of cholecalciferol is a safe and effective therapy for treatment of VDD rickets in infants and toddlers with normalization of all the biochemical parameters and healing of radiological manifestations. "
09/01/1984 - "Parenteral cholecalciferol is a safe and effective therapy for the treatment and prevention of childhood rickets."
09/01/1984 - "The safety and efficacy of parenteral cholecalciferol was evaluated in the treatment and prevention of childhood rickets. "
10/01/2005 - "An overall evaluation of the study indicates that chicks from hens fed the highest levels of vitamin D3 and fed high levels of Ca or 25-OHD3 had the highest BWG, tibia ash, and plasma Ca, and the lowest incidences of TD and Ca rickets."

08/01/2012 - "Furthermore, published case studies on experiences with using calcitriol as a potential therapeutic for rickets in premature infants are very rare. "
08/01/2012 - "Herein, we describe the detection of rickets in premature infants and our experience with calcitriol treatment in two premature infants. "
08/01/2012 - "Detecting rickets in premature infants and treating them with calcitriol: experience from two cases."
05/01/1999 - "Conventional therapy of hypophosphataemic rickets (HR) with oral phosphate and calcitriol does not always result in normal linear growth. "
11/01/1998 - "One patient receiving a low dose of 20 ng/kg per day calcitriol had prolonged radiological and biochemical signs of rickets and growth delay. "

01/01/1986 - "The higher vit D level significantly enhanced growth, bone ash, and reduced incidence of rickets, although it had no effect on incidence of TD."
03/01/2004 - "The diets with 0.5% P resulted in overall poorer performance as 16-d BW was reduced, gain:feed ratio decreased, bone ash decreased, and rickets incidence increased. "
07/01/2003 - "However, when not exposed on day 1, but on days 4, 7, 10, 13 and 16, the bone ash was reduced, and the incidence of TD and rickets was increased, compared with chickens exposed on day 1 after hatching. "
01/01/1999 - "Extrusion of the diet did not influence bone ash and P rickets, both sensitive criteria of P deficiency. "
05/01/1990 - "The reduction in bone ash was relatively mild, and no clinical signs of rickets were observed. "

06/01/1996 - "Radiographic features of rickets improved during 24,25(OH)2 D3 supplementation in children, and osteoid surface decreased in adults. "
08/01/2007 - "There was fair evidence from studies of an association between circulating 25(OH)D concentrations with some bone health outcomes (established rickets, PTH, falls, BMD). "
01/01/1984 - "The ability of 1,25(OH)2D3 and of 24,25(OH)2D3 to prevent or to heal rickets in chicks was evaluated by studies of plasma biochemistry, growth plate histology, bone morphometry and microradiography, and bone mineralization. "
12/01/2012 - "Hereditary 1,25-dihydroxyvitamin-D [1,25(OH)(2)D(3)]-resistant rickets (HVDRR) is a rare genetic disease caused by generalized resistance to 1,25(OH)(2)D(3). "
10/01/2012 - "Therefore, it may be useful to check serum 25(OH)D levels in screening for rickets."

10/01/1979 - "The serum phosphorus improved from 2.2 to 4.3 mg/dl and radiologic healing of rickets was documented. "
09/30/1922 - "Rats on a low phosphorus diet cannot be protected from the development of rickets by exposures to soft Roentgen rays such as were employed in this study. "
09/01/2011 - "Phosphorus-deficient diets were formulated to induce P rickets with 2 different P sources. "
10/01/2007 - "In addition, serum phosphorus level should also be questioned in the diagnosis of nutritional rickets."
03/01/2007 - "Thirty per cent of children with rickets were hypocalcaemic vs <7% of controls, 89% had phosphorus values <1.5 mmol/L vs 34.5% of controls and 75% had alkaline phosphatise levels >500 IU/L vs 28% of controls. "

07/01/1968 - "[Contribution to the study of vitamin-resistant rickets. "
01/01/1967 - "Studies on the dynamics of skeletal calcification during treatment of vitamin-deficient rickets in infants."
03/14/1961 - "[Study on idiopathic hypophosphatemic vitamin-resistant rickets in children]."
01/01/1961 - "[Idiopathic hypophosphatemic vitamin-resistant rickets in children (Attempted dissociation of 2 different diseases by clinical, radiological, biological and genetic studies)]."
11/01/1960 - "[Study on idiopathic hypophosphatemic vitamin-resistant rickets]."

07/01/1998 - "It soon became apparent that rickets could be cured by supplementing the diet with cod liver oil and exposure to sunlight. "
01/01/2013 - "This is because older supplementation recommendations were based on early twentieth century studies using cod-liver oil to treat rickets. "
04/01/2011 - "Our study relates the story of fight against rickets in France, from the use of cod liver oil to the synthesis of Vitamine D."
10/01/2014 - "We hypothesised that cod liver oil (CLO) consumers are similar to non-supplement users, since CLO use might originate from historical motives, i.e., rickets prevention, and not health consciousness. "
12/01/2009 - "English cities in 1880 were characterized by an extremely high rickets prevalence, the beginning of commercial cod liver oil production, and the near absence of any allergic diseases. "

07/01/2010 - "We included all patients referred to our clinic with active rickets after a failed course of alphacalcidol. "
06/01/1996 - "They were initially treated with 1 alpha-hydroxyvitamin D3 (1 alpha OHD3) and later with 1 alpha OHD3 in combination with Pi, which results in healing of the rickets and a normal increase in height. "
02/01/1988 - "The patient presented with severe rickets despite therapy with extraordinarily high doses of 1 alpha-hydroxyvitamin D3 or 1,25-(OH)2D3. "
01/01/1987 - "[Oksidevit in the combined prevention of rickets in premature children]."
11/01/1982 - "Although 4 infants received alfacalcidol which healed the rickets, in 4 infants the rickets healed spontaneously without change in treatment. "

06/01/2004 - "If bone marrow transplantation is feasible, then for better results, rickets should be completely treated prior to the transplantation."
11/01/1996 - "Hypophosphatemia induced in mice by transplantation of a tumor-derived cell line from a patient with oncogenic rickets."
01/01/2012 - "This includes patients in whom a "reasonably" evidence-based target concentration (i.e., based on randomized clinical trials when possible) should be achieved and/or maintained such as patients with rickets/osteomalacia, osteoporosis, chronic kidney disease and kidney transplant recipients, malabsorption, primary hyperparathyroidism, granulomatous disease, and those receiving treatments potentially inducing bone loss. "
12/01/1985 - "Such biochemic and morphologic manifestations of rickets in this osteopetrotic mutation may explain the failure of osteosclerotic mice to be cured by transplantation of bone marrow from normal littermates and indicate that vitamin D metabolism and matrix vesicle biochemistry warrant further study."
02/01/1993 - "Nonrenal complications of infantile cystinosis present before transplantation were photophobia (n = 3), corneal crystals (n = 5), hypothyroidism (n = 1), rickets (n = 6), and short stature (n = 7). "

10/01/2004 - "Rickets should be identified and treated at the onset, because treatment of rickets leads to improvement in well-being and an adequate clinical response to bone marrow transplantation."
12/01/2009 - "We report a patient with an unusual case of infantile osteopetro-rickets who was admitted with anterior fontanel bulging and was treated with haploidentical bone marrow transplantation."
06/01/2004 - "If bone marrow transplantation is feasible, then for better results, rickets should be completely treated prior to the transplantation."
09/01/1996 - "Current opinion regarding the clinical treatment of patients with osteopetrorickets involves first, the resolution of the rickets, followed by bone marrow transplantation to resolve the osteopetrosis, although this has not been successfully performed in humans. "
04/01/2003 - "An 8-month-old girl who seemed certain to die from the infantile form of hypophosphatasia, an inborn error of metabolism characterized by deficient activity of the tissue-nonspecific isoenzyme of alkaline phosphatase (TNSALP), underwent the first trial of bone marrow cell transplantation for this heritable type of rickets. "

07/01/1987 - "Pigs with florid rickets and hypocalcaemia were treated with single im injections of 0.25 to 1.25 mg of vitamin D3, doses that have been shown in previous studies to be effective in producing transient healing of rachitic symptoms. "
07/01/2009 - "Comparison of oral versus injectable vitamin-D for the treatment of nutritional vitamin-D deficiency rickets."

07/01/2007 - "Despite improved prenatal care offered today, congenital rickets still occurs. "

02/01/1990 - "Our results indicate that adequate doses of 1 alpha-D3 and calcium carbonate are effective in the prevention of ROD and rickets in patients on CAPD."