Ribose (D-Ribose)

01/01/2003 - "In SHR, ribose pretreatment did not produce significant elevations in the heart's energy or improvements in tolerance to global ischemia, but significantly improved ventricular function (maximal rate of pressure rise (+dP/dt(max)), 25%; normalized contractility ((+dP/dt)/P), 13%) despite no change in hemodynamics. "
05/01/2009 - "Thus, D-ribose ameliorates the I/R-induced renal injury probably by inhibiting neutrophil activation, and may be useful in attenuating the renal injury associated with renal ischemia."
09/01/2007 - "D-Ribose (R) has been shown to improve cardiac function and energy status after ischemia. "
05/01/2009 - "D-ribose attenuates ischemia/reperfusion-induced renal injury by reducing neutrophil activation in rats."
12/01/1988 - "Alteration of 201Tl kinetics by ribose may permit earlier recognition of 201Tl myocardial redistribution after transient ischemia."

09/11/2009 - "Ribose improved the ventilatory exercise status in advanced heart failure patients."
06/01/2015 - "This study investigated what role D-ribose might play in congestive heart failure patients with preserved systolic function and diastolic dysfunction. "
09/11/2009 - "As current pharmaceuticals do not address cellular energy levels, this study was designed to investigate the role of ribose on ventilation at anaerobic threshold in congestive heart failure patients. "
01/01/2004 - "Clinical trials have shown that ribose supplementation improves ischemic threshold and enhances diastolic function in congestive heart failure."
05/01/2021 - "D-ribose: Potential clinical applications in congestive heart failure and diabetes, and its complications (Review)."

01/01/2020 - "These effects are accompanied by a marked reduction in atherosclerosis suggesting that ribose-cysteine might increase protection against CVD."
04/15/2016 - "Antigenic role of the adaptive immune response to d-ribose glycated LDL in diabetes, atherosclerosis and diabetes atherosclerotic patients."
01/01/2020 - "Ribose-cysteine protects against the development of atherosclerosis in apoE-deficient mice."
12/01/2014 - "As ribose-cysteine lowers LDL, Lp(a) and oxidised lipid concentrations, it might be an ideal intervention to increase protection against the development of atherosclerosis."
01/01/2020 - "Here we investigate the effect of ribose-cysteine on GSH, GPx, oxidised lipids and atherosclerosis development in apolipoprotein E-deficient (apoE-/-) mice. "

01/01/2017 - "Clinical trials have demonstrated successful treatment of homologous recombination-defective cancers with poly-ribose polymerase inhibitors through synthetic lethality. "
08/22/2011 - "Studies in human epithelial-derived malignancies indicate that K+ depletion also occurs, contributing to the increased intracellular Na+/K+ ratio 1. D-ribose transformed to piruvate, enters into the Krebs's cycle and has a key role on energetic metabolism. "
05/01/2023 - "Reinforcement of the Tumor Suppressing Properties of microRNA-1 by Substitution at the C2' Position of Varying Ribose Residues in Chemically Synthesized microRNA-1 Molecules."
01/01/2020 - "Altogether, we demonstrate this probe's utilities to uncover ribose-glycation and deglycation events as well as track FN3K activity toward establishing its potential as a new cancer vulnerability."
03/15/2008 - "Tumor cells extensively utilize the pentose phosphate pathway for the synthesis of ribose. "

01/01/2003 - "For study 1, Sprague-Dawley rats received equal volumes of either vehicle (bolus i.v. saline) or ribose (100 mg/kg) before global myocardial ischemia. "
01/01/2003 - "Thus, administration of ribose in advance of global myocardial ischemia does provide metabolic benefit in normal hearts. "
10/01/2000 - "In support of this hypothesis, recent reports have used D-ribose to increase tolerance to myocardial ischemia. "
12/17/2019 - "The aim of this study is to establish whether a supplement of creatine and ribose combined with a physical exercise program can improve the total work capacity during exercise in a population of patients with known ischemic heart disease. "
12/17/2019 - "A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effectiveness of a Food Supplement Containing Creatine and D-Ribose Combined with a Physical Exercise Program in Increasing Stress Tolerance in Patients with Ischemic Heart Disease."